Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   I6J38_RS06540 Genome accession   NZ_CP069558
Coordinates   1320344..1321285 (-) Length   313 a.a.
NCBI ID   WP_006268058.1    Uniprot ID   F9P809
Organism   Streptococcus constellatus strain FDAARGOS_1208     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1315344..1326285
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J38_RS06500 (I6J38_06500) - 1315401..1316600 (-) 1200 WP_006267970.1 acetate kinase -
  I6J38_RS06505 (I6J38_06505) comYH 1316647..1317600 (-) 954 WP_020998065.1 class I SAM-dependent methyltransferase Machinery gene
  I6J38_RS06510 (I6J38_06510) comGG 1317685..1318011 (-) 327 WP_020998066.1 competence type IV pilus minor pilin ComGG -
  I6J38_RS06515 (I6J38_06515) comGF/cglF 1317992..1318429 (-) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6J38_RS06520 (I6J38_06520) comGE/cglE 1318413..1318706 (-) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6J38_RS06525 (I6J38_06525) comYD 1318678..1319106 (-) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6J38_RS06530 (I6J38_06530) comYC 1319066..1319383 (-) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  I6J38_RS06535 (I6J38_06535) comYB 1319380..1320402 (-) 1023 WP_037592679.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6J38_RS06540 (I6J38_06540) comYA 1320344..1321285 (-) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  I6J38_RS06545 (I6J38_06545) - 1321355..1321720 (-) 366 WP_022525692.1 DUF1033 family protein -
  I6J38_RS06550 (I6J38_06550) glnA 1321908..1323254 (-) 1347 WP_020998070.1 type I glutamate--ammonia ligase -
  I6J38_RS06555 (I6J38_06555) - 1323293..1323652 (-) 360 WP_003073972.1 MerR family transcriptional regulator -
  I6J38_RS06560 (I6J38_06560) - 1323729..1324259 (-) 531 WP_006268314.1 FUSC family protein -
  I6J38_RS06565 (I6J38_06565) - 1324398..1324682 (-) 285 WP_006268247.1 2'-5' RNA ligase family protein -
  I6J38_RS06570 (I6J38_06570) - 1324685..1324891 (-) 207 WP_006268044.1 hypothetical protein -
  I6J38_RS06575 (I6J38_06575) - 1324957..1326153 (-) 1197 WP_006268026.1 phosphoglycerate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35973.15 Da        Isoelectric Point: 6.3145

>NTDB_id=535541 I6J38_RS06540 WP_006268058.1 1320344..1321285(-) (comYA) [Streptococcus constellatus strain FDAARGOS_1208]
MVQNIAQAIICQAKEERAQDIYFVPKENVYELYMRIGDERRFIRNYEFEELAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YSDKKTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFANQQ
IMSIEDPVEIKQAGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSERYQEHEPSDWNKQIDQLYAAGHITFEQAETEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=535541 I6J38_RS06540 WP_006268058.1 1320344..1321285(-) (comYA) [Streptococcus constellatus strain FDAARGOS_1208]
ATGGTTCAAAACATTGCACAGGCTATTATTTGTCAGGCTAAGGAAGAACGAGCACAGGACATTTATTTTGTTCCGAAGGA
AAATGTTTACGAGTTGTATATGCGAATTGGAGATGAACGCCGTTTTATACGCAATTATGAATTTGAAGAGCTAGCTGCTG
TAATCAGTCATTTTAAGTTTACTGCTGGGATGAATGTGGGAGAAAAACGTCGCAGTCAGCTGGGCTCTTGCGATTATCAA
TATAGTGACAAGAAAACGTCGCTACGGTTATCAACAGTGGGGGATTATCGCGGATATGAAAGTCTAGTGATTCGTCTATT
GCATGATGAAGAAGCAGAGCTGAAGTTTTGGTTTGCTCAAATTCCGGAGTTGAAAGAACGTTTCAAACAGCGAGGGCTTT
ACCTTTTTTCAGGACCGGTAGGAAGTGGTAAAACTACTCTCATGCACCAGTTGGCTCAAGAGCGTTTTGCCAATCAGCAA
ATCATGTCAATTGAAGATCCGGTTGAAATCAAACAAGCAGGGATGTTACAGCTGCAGCTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGGCATCGACCAGATTTATTGATTATCGGAGAGATTCGTGATGCGGAGACAG
CACGGGCAGTTGTTCGAGCTAGCTTAACGGGAGTGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGCTGGAGTTGGGAGTGACAGAAGCAGAGCTGAAAATTGTTTTGCAAGGAATTTGCTACCAACGGTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAAAGGTATCAAGAGCATGAGCCAAGTGACTGGAATAAGCAGATTGATCAGC
TTTATGCAGCAGGACATATCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P809

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

83.226

99.042

0.824
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

76.038

100

0.76
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.719

100

0.757
  comYA Streptococcus mutans UA159

64.63

99.361

0.642
  comYA Streptococcus mutans UA140

64.63

99.361

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.662

99.361

0.543
  comGA Latilactobacillus sakei subsp. sakei 23K

43.478

88.179

0.383