Detailed information NTG0535539

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: I6J38_RS06530
• Genome accession: NZ_CP069558
• Coordinates: 1319066..1319383 (-)
• Length: 105 a.a.
• NCBI ID: WP_020998068.1
• Uniprot ID: U2XY26
• Organism: Streptococcus constellatus strain FDAARGOS_1208
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1314066..1324383

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J38_RS06500 (I6J38_06500)	-	1315401..1316600 (-)	1200	WP_006267970.1	acetate kinase	-
I6J38_RS06505 (I6J38_06505)	comYH	1316647..1317600 (-)	954	WP_020998065.1	class I SAM-dependent methyltransferase	Machinery gene
I6J38_RS06510 (I6J38_06510)	comGG	1317685..1318011 (-)	327	WP_020998066.1	competence type IV pilus minor pilin ComGG	-
I6J38_RS06515 (I6J38_06515)	comGF/cglF	1317992..1318429 (-)	438	WP_003035329.1	competence type IV pilus minor pilin ComGF	Machinery gene
I6J38_RS06520 (I6J38_06520)	comGE/cglE	1318413..1318706 (-)	294	WP_003035318.1	competence type IV pilus minor pilin ComGE	Machinery gene
I6J38_RS06525 (I6J38_06525)	comYD	1318678..1319106 (-)	429	WP_020999411.1	competence type IV pilus minor pilin ComGD	Machinery gene
I6J38_RS06530 (I6J38_06530)	comYC	1319066..1319383 (-)	318	WP_020998068.1	competence type IV pilus major pilin ComGC	Machinery gene
I6J38_RS06535 (I6J38_06535)	comYB	1319380..1320402 (-)	1023	WP_037592679.1	competence type IV pilus assembly protein ComGB	Machinery gene
I6J38_RS06540 (I6J38_06540)	comYA	1320344..1321285 (-)	942	WP_006268058.1	competence type IV pilus ATPase ComGA	Machinery gene
I6J38_RS06545 (I6J38_06545)	-	1321355..1321720 (-)	366	WP_022525692.1	DUF1033 family protein	-
I6J38_RS06550 (I6J38_06550)	glnA	1321908..1323254 (-)	1347	WP_020998070.1	type I glutamate--ammonia ligase	-
I6J38_RS06555 (I6J38_06555)	-	1323293..1323652 (-)	360	WP_003073972.1	MerR family transcriptional regulator	-
I6J38_RS06560 (I6J38_06560)	-	1323729..1324259 (-)	531	WP_006268314.1	FUSC family protein	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11678.82 Da
• Isoelectric Point: 10.1006

>NTDB_id=535539 I6J38_RS06530 WP_020998068.1 1319066..1319383(-) (comYC) [Streptococcus constellatus strain FDAARGOS_1208]
MKKIKNIKVKAFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVSEGT
ITDKQAVSYKAYYAKHTKEARTVAD

Nucleotide

• Length: 318 bp

>NTDB_id=535539 I6J38_RS06530 WP_020998068.1 1319066..1319383(-) (comYC) [Streptococcus constellatus strain FDAARGOS_1208]
ATGAAAAAAATTAAAAATATAAAGGTAAAAGCTTTCACTTTGGTAGAAATGTTAGTGGTGCTTCTAATCATCAGTGTTTT
GATGCTTTTGTTTGTTCCGAATTTGACCAAACAAAAAGAAGCTGTAACGGAAAAAGGAAATGCAGCTGTTGTGAAGGTTG
TCGAAAGTCAGGCAGAGCTTTTTGAAGTGAATCATACTAATGAAAAAGCGACGCTTTCAAAATTAGTCAGTGAAGGAACT
ATTACAGACAAGCAAGCAGTATCATACAAGGCTTATTATGCAAAACATACAAAAGAAGCTCGCACAGTTGCAGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: U2XY26

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	72.381	100	0.724
comYC	Streptococcus mutans UA140	68.571	100	0.686
comYC	Streptococcus mutans UA159	68.571	100	0.686
comGC/cglC	Streptococcus mitis NCTC 12261	69.608	97.143	0.676
comGC/cglC	Streptococcus mitis SK321	68.627	97.143	0.667
comGC/cglC	Streptococcus pneumoniae Rx1	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae D39	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae TIGR4	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae R6	66.667	97.143	0.648
comGC	Lactococcus lactis subsp. cremoris KW2	55.769	99.048	0.552
comYC	Streptococcus suis isolate S10	64.045	84.762	0.543