Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   I6J38_RS06520 Genome accession   NZ_CP069558
Coordinates   1318413..1318706 (-) Length   97 a.a.
NCBI ID   WP_003035318.1    Uniprot ID   I0SGQ0
Organism   Streptococcus constellatus strain FDAARGOS_1208     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1313413..1323706
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J38_RS06500 (I6J38_06500) - 1315401..1316600 (-) 1200 WP_006267970.1 acetate kinase -
  I6J38_RS06505 (I6J38_06505) comYH 1316647..1317600 (-) 954 WP_020998065.1 class I SAM-dependent methyltransferase Machinery gene
  I6J38_RS06510 (I6J38_06510) comGG 1317685..1318011 (-) 327 WP_020998066.1 competence type IV pilus minor pilin ComGG -
  I6J38_RS06515 (I6J38_06515) comGF/cglF 1317992..1318429 (-) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6J38_RS06520 (I6J38_06520) comGE/cglE 1318413..1318706 (-) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6J38_RS06525 (I6J38_06525) comYD 1318678..1319106 (-) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6J38_RS06530 (I6J38_06530) comYC 1319066..1319383 (-) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  I6J38_RS06535 (I6J38_06535) comYB 1319380..1320402 (-) 1023 WP_037592679.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6J38_RS06540 (I6J38_06540) comYA 1320344..1321285 (-) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  I6J38_RS06545 (I6J38_06545) - 1321355..1321720 (-) 366 WP_022525692.1 DUF1033 family protein -
  I6J38_RS06550 (I6J38_06550) glnA 1321908..1323254 (-) 1347 WP_020998070.1 type I glutamate--ammonia ligase -
  I6J38_RS06555 (I6J38_06555) - 1323293..1323652 (-) 360 WP_003073972.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10936.85 Da        Isoelectric Point: 10.4707

>NTDB_id=535537 I6J38_RS06520 WP_003035318.1 1318413..1318706(-) (comGE/cglE) [Streptococcus constellatus strain FDAARGOS_1208]
MENLRKQYVRGTILLEALLASAVFAFIVTLLLGQIHQSRQTENDLLKKEEVLRVANMALQTKQSHLTINGIEVRVKKSQQ
GIQIYHGKELIVGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=535537 I6J38_RS06520 WP_003035318.1 1318413..1318706(-) (comGE/cglE) [Streptococcus constellatus strain FDAARGOS_1208]
ATGGAAAATTTAAGAAAACAATACGTTAGAGGAACGATTTTATTAGAAGCTTTATTGGCATCGGCTGTTTTTGCGTTTAT
TGTGACCTTGTTATTGGGGCAGATCCATCAGTCTCGACAGACAGAAAATGATTTACTGAAAAAAGAAGAAGTTCTAAGAG
TGGCTAATATGGCATTACAAACAAAGCAAAGCCATTTAACAATAAACGGTATTGAAGTTCGTGTTAAAAAAAGTCAACAA
GGCATCCAGATTTATCATGGGAAGGAGCTGATTGTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SGQ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae D39

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae R6

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae TIGR4

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis NCTC 12261

54.348

94.845

0.515
  comGE/cglE Streptococcus mitis SK321

54.348

94.845

0.515
  comYE Streptococcus mutans UA140

42.424

100

0.433
  comYE Streptococcus mutans UA159

42.424

100

0.433