Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   K6969_RS01340 Genome accession   NZ_CP082205
Coordinates   235561..236511 (+) Length   316 a.a.
NCBI ID   WP_171942940.1    Uniprot ID   -
Organism   Streptococcus suis strain AKJ18     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 230561..241511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS01315 (K6969_01285) - 230907..231227 (+) 321 WP_044760034.1 PTS sugar transporter subunit IIB -
  K6969_RS01320 (K6969_01290) - 231231..231572 (+) 342 WP_044760035.1 PTS lactose/cellobiose transporter subunit IIA -
  K6969_RS01325 (K6969_01295) - 231572..232927 (+) 1356 WP_044760036.1 PTS sugar transporter subunit IIC -
  K6969_RS01330 (K6969_01300) - 233026..234402 (-) 1377 WP_414820583.1 IS1182 family transposase -
  K6969_RS01335 (K6969_01305) - 234507..235475 (-) 969 WP_321537437.1 S66 peptidase family protein -
  K6969_RS01340 (K6969_01310) comGA 235561..236511 (+) 951 WP_171942940.1 competence type IV pilus ATPase ComGA Machinery gene
  K6969_RS01345 (K6969_01315) comGB 236423..237460 (+) 1038 WP_253911821.1 competence type IV pilus assembly protein ComGB Machinery gene
  K6969_RS01350 (K6969_01320) comGC 237462..237743 (+) 282 WP_171942939.1 competence type IV pilus major pilin ComGC Machinery gene
  K6969_RS01355 (K6969_01325) comGD 237724..238131 (+) 408 WP_171942938.1 competence type IV pilus minor pilin ComGD Machinery gene
  K6969_RS01360 (K6969_01330) comGE 238103..238396 (+) 294 WP_024376294.1 competence type IV pilus minor pilin ComGE Machinery gene
  K6969_RS01365 (K6969_01335) comGF/cglF 238383..238817 (+) 435 WP_029173990.1 competence type IV pilus minor pilin ComGF Machinery gene
  K6969_RS01370 (K6969_01340) comGG 238795..239322 (+) 528 WP_029173991.1 competence type IV pilus minor pilin ComGG -
  K6969_RS01375 (K6969_01345) comGH 239379..240332 (+) 954 WP_029173992.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35456.23 Da        Isoelectric Point: 5.1569

>NTDB_id=527317 K6969_RS01340 WP_171942940.1 235561..236511(+) (comGA) [Streptococcus suis strain AKJ18]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDVAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFANGDYQNHSANQWNEQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=527317 K6969_RS01340 WP_171942940.1 235561..236511(+) (comGA) [Streptococcus suis strain AKJ18]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTACCATCGTATCATGGACGAGCGGGAGTTTGTGCAAGACGTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAGCAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATTTGATAAAATTATCCCTGCGTCATCGACCGGACCTGCTCATCATCGGTGAAATTCGGGATGCAGAAACGG
CTCGAGCAGTCATTCGAGCCAGTCTGACAGGTGCGACTGTCTTCTCAACGGTGCATGCAAGGTCTATTTCGGGTGTCTAT
GCTCGTATGTTGGAATTGGGGGTCAGCCCTGAAGAGTTAAATAATGCCCTTCAAGGAATTGCCTATCAACGATTAATCGG
GGGAGGAGGTGTAGTGGATTTTGCAAATGGAGACTACCAAAACCATTCCGCAAACCAGTGGAATGAACAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comGA Streptococcus mutans UA159

67.846

98.418

0.668
  comGA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

98.418

0.646
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.161

98.101

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.628

100

0.538