Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   K6969_RS01345 Genome accession   NZ_CP082205
Coordinates   236423..237460 (+) Length   345 a.a.
NCBI ID   WP_253911821.1    Uniprot ID   -
Organism   Streptococcus suis strain AKJ18     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 231423..242460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS01325 (K6969_01295) - 231572..232927 (+) 1356 WP_044760036.1 PTS sugar transporter subunit IIC -
  K6969_RS01330 (K6969_01300) - 233026..234402 (-) 1377 WP_414820583.1 IS1182 family transposase -
  K6969_RS01335 (K6969_01305) - 234507..235475 (-) 969 WP_321537437.1 S66 peptidase family protein -
  K6969_RS01340 (K6969_01310) comGA 235561..236511 (+) 951 WP_171942940.1 competence type IV pilus ATPase ComGA Machinery gene
  K6969_RS01345 (K6969_01315) comGB 236423..237460 (+) 1038 WP_253911821.1 competence type IV pilus assembly protein ComGB Machinery gene
  K6969_RS01350 (K6969_01320) comGC 237462..237743 (+) 282 WP_171942939.1 competence type IV pilus major pilin ComGC Machinery gene
  K6969_RS01355 (K6969_01325) comGD 237724..238131 (+) 408 WP_171942938.1 competence type IV pilus minor pilin ComGD Machinery gene
  K6969_RS01360 (K6969_01330) comGE 238103..238396 (+) 294 WP_024376294.1 competence type IV pilus minor pilin ComGE Machinery gene
  K6969_RS01365 (K6969_01335) comGF/cglF 238383..238817 (+) 435 WP_029173990.1 competence type IV pilus minor pilin ComGF Machinery gene
  K6969_RS01370 (K6969_01340) comGG 238795..239322 (+) 528 WP_029173991.1 competence type IV pilus minor pilin ComGG -
  K6969_RS01375 (K6969_01345) comGH 239379..240332 (+) 954 WP_029173992.1 class I SAM-dependent methyltransferase Machinery gene
  K6969_RS01380 (K6969_01350) - 240383..241570 (+) 1188 WP_171942932.1 acetate kinase -
  K6969_RS01385 (K6969_01355) - 241885..242436 (+) 552 WP_171942931.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 39017.03 Da        Isoelectric Point: 9.4808

>NTDB_id=527318 K6969_RS01345 WP_253911821.1 236423..237460(+) (comGB) [Streptococcus suis strain AKJ18]
MNKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSNGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPVILLGFLLLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVVVLAGMVWFRKTNKIKVFSRLAALPFFGKLIQIYLTAYYAREWGSLIGQGLDLPQIVSLMQS
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKWELSLIAEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=527318 K6969_RS01345 WP_253911821.1 236423..237460(+) (comGB) [Streptococcus suis strain AKJ18]
ATGAACAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAACTGTTTAACAATCTCTTTGCTAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GTAGTCAGCTTTTAGCAGATCCTTACACTCAGGTTTTGTCGAATGGCCTTCTTGCAGGGAAGCCCTTTTCAAGTTTGCTG
GCGGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAAGTTCATGGTAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCGGTAATCTTGC
TTGGTTTTCTGCTTTTGATTATGCTAGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAAGAAGGTAATGCAGCGACTATG
CTAATTAATCATCTGCCGACTATCTTTCTATCCCTCTGTGGACTTAGTTTGGTGGTGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACCAACAAAATCAAGGTCTTTTCCCGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAATCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGAGCTTGATGCAATCG
CAGCAATCGCAGCTCTTTCGGGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGTGGGAGCTGAGTTTGATTGCCGAGTATGGTCAGGTCAAGTCCAAGTTAGGTAGCGAGT
TGACAGTTTATGCGGCTGAGTGTTGGGAGGATTTCTTCTCTCGGGTCAATAGAGCCATGCAGCTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTTATCTACGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGTTATAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Streptococcus gordonii str. Challis substr. CH1

63.743

99.13

0.632
  comGB/cglB Streptococcus mitis NCTC 12261

60.299

97.101

0.586
  comGB Streptococcus mutans UA140

58.892

99.42

0.586
  comGB Streptococcus mutans UA159

58.892

99.42

0.586
  comGB/cglB Streptococcus mitis SK321

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae Rx1

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae D39

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae R6

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae TIGR4

59.701

97.101

0.58
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

97.681

0.496