Detailed information NTG0527322

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: K6969_RS01365
• Genome accession: NZ_CP082205
• Coordinates: 238383..238817 (+)
• Length: 144 a.a.
• NCBI ID: WP_029173990.1
• Uniprot ID: -
• Organism: Streptococcus suis strain AKJ18
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 233383..243817

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6969_RS01335 (K6969_01305)	-	234507..235475 (-)	969	WP_321537437.1	S66 peptidase family protein	-
K6969_RS01340 (K6969_01310)	comGA	235561..236511 (+)	951	WP_171942940.1	competence type IV pilus ATPase ComGA	Machinery gene
K6969_RS01345 (K6969_01315)	comGB	236423..237460 (+)	1038	WP_253911821.1	competence type IV pilus assembly protein ComGB	Machinery gene
K6969_RS01350 (K6969_01320)	comGC	237462..237743 (+)	282	WP_171942939.1	competence type IV pilus major pilin ComGC	Machinery gene
K6969_RS01355 (K6969_01325)	comGD	237724..238131 (+)	408	WP_171942938.1	competence type IV pilus minor pilin ComGD	Machinery gene
K6969_RS01360 (K6969_01330)	comGE	238103..238396 (+)	294	WP_024376294.1	competence type IV pilus minor pilin ComGE	Machinery gene
K6969_RS01365 (K6969_01335)	comGF/cglF	238383..238817 (+)	435	WP_029173990.1	competence type IV pilus minor pilin ComGF	Machinery gene
K6969_RS01370 (K6969_01340)	comGG	238795..239322 (+)	528	WP_029173991.1	competence type IV pilus minor pilin ComGG	-
K6969_RS01375 (K6969_01345)	comGH	239379..240332 (+)	954	WP_029173992.1	class I SAM-dependent methyltransferase	Machinery gene
K6969_RS01380 (K6969_01350)	-	240383..241570 (+)	1188	WP_171942932.1	acetate kinase	-
K6969_RS01385 (K6969_01355)	-	241885..242436 (+)	552	WP_171942931.1	folate family ECF transporter S component	-
K6969_RS01390 (K6969_01360)	-	242490..243746 (+)	1257	WP_171942930.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16449.77 Da
• Isoelectric Point: 6.9832

>NTDB_id=527322 K6969_RS01365 WP_029173990.1 238383..238817(+) (comGF/cglF) [Streptococcus suis strain AKJ18]
MLKSKIPAFTLLECLVALVILSGSLLVFESLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVNKGE
QALAFGKSRSDDFRKTNDRGQGYQPMIYQVDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=527322 K6969_RS01365 WP_029173990.1 238383..238817(+) (comGF/cglF) [Streptococcus suis strain AKJ18]
TTGTTAAAAAGTAAAATTCCTGCTTTTACTCTCCTGGAATGCTTGGTAGCCTTAGTCATCCTATCAGGAAGTCTTCTGGT
CTTTGAAAGCTTGTCAAAACTGTTGGTTCAAGAGGCGCATTACCAAGGTCAGACTGTTCAAAAGGAATGGTTGGTCTTCT
CTAGTCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCAACAAAGGCGAA
CAGGCTTTAGCCTTTGGCAAGTCACGGTCGGATGATTTTCGGAAAACAAATGACAGGGGACAGGGCTATCAGCCCATGAT
TTATCAAGTAGACAGCGCAGCTATTTCTCAAGAAAACCAGCTGGTGCGTATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GGACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae TIGR4	53.191	97.917	0.521
comGF/cglF	Streptococcus pneumoniae Rx1	53.191	97.917	0.521
comGF/cglF	Streptococcus pneumoniae D39	53.191	97.917	0.521
comGF/cglF	Streptococcus pneumoniae R6	53.191	97.917	0.521
comGF/cglF	Streptococcus mitis NCTC 12261	53.731	93.056	0.5
comGF	Streptococcus mutans UA140	48.611	100	0.486
comGF	Streptococcus mutans UA159	47.917	100	0.479
comGF/cglF	Streptococcus mitis SK321	50.746	93.056	0.472
comGF	Lactococcus lactis subsp. cremoris KW2	45.39	97.917	0.444