Detailed information NTG0051906

Bioinformatically predicted

Overview

• Name: comE
• Type: Regulator
• Locus tag: SCIM_RS09470
• Genome accession: NC_018073
• Coordinates: 1928176..1928925 (-)
• Length: 249 a.a.
• NCBI ID: WP_003075577.1
• Uniprot ID: -
• Organism: Streptococcus intermedius JTH08
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1923176..1933925

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCIM_RS09450 (SCIM_1701)	-	1923580..1925202 (+)	1623	WP_003077196.1	ATP-binding cassette domain-containing protein	-
SCIM_RS09455 (SCIM_1702)	-	1925276..1927852 (+)	2577	WP_003077344.1	YfhO family protein	-
SCIM_RS09470 (SCIM_1703)	comE	1928176..1928925 (-)	750	WP_003075577.1	competence system response regulator transcription factor ComE	Regulator
SCIM_RS09475 (SCIM_1704)	comD/comD1	1928925..1930250 (-)	1326	WP_014829844.1	GHKL domain-containing protein	Regulator
SCIM_RS09775	-	1930267..1930413 (-)	147	WP_003075491.1	bacteriocin	-
SCIM_RS09490 (SCIM_1705)	rlmH	1930690..1931169 (-)	480	WP_003075603.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SCIM_RS09495 (SCIM_1706)	htrA	1931373..1932563 (+)	1191	WP_003075586.1	S1C family serine protease	Regulator
SCIM_RS09500 (SCIM_1707)	spo0J	1932618..1933385 (+)	768	WP_003075591.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29234.80 Da
• Isoelectric Point: 8.0443

>NTDB_id=51906 SCIM_RS09470 WP_003075577.1 1928176..1928925(-) (comE) [Streptococcus intermedius JTH08]
MKVLVLEDEISHQVRMETTLAEIAKEMGISIKVKVTGKIREFKEYIENDEVNQLYFLDIDIKGEETKGLEIAKFIRHHNP
YAIIVFVTTKSEFATMTFKYKVSALDFVDKNLNDVAFKKHIKDNIEYTKATLIENKDMVDYFEYSFRGGEVRMPFNDILY
IETTGSSHKLRIVGKNFFKEFYGTIADIQEKDKETQRFFSPHKSYLVNIGNIKSYDKKMKEIIFYEDHRCPITRMKIGKL
KTILEESKG

Nucleotide

• Length: 750 bp

>NTDB_id=51906 SCIM_RS09470 WP_003075577.1 1928176..1928925(-) (comE) [Streptococcus intermedius JTH08]
ATGAAAGTATTAGTATTAGAAGATGAAATTTCACATCAAGTAAGAATGGAAACAACTTTGGCAGAGATTGCAAAAGAAAT
GGGAATTTCTATCAAAGTTAAAGTAACTGGAAAAATAAGAGAATTTAAAGAATATATTGAGAATGATGAAGTAAATCAAT
TATACTTTTTAGATATTGATATTAAAGGGGAAGAGACAAAAGGTTTAGAAATAGCAAAATTTATACGTCATCATAATCCG
TATGCTATTATTGTTTTTGTTACAACGAAATCAGAATTTGCTACTATGACTTTTAAATATAAAGTTTCTGCACTAGATTT
TGTTGATAAAAATTTGAATGATGTTGCTTTTAAAAAACATATAAAAGATAATATCGAGTATACAAAAGCAACGTTGATTG
AAAATAAAGATATGGTTGATTATTTTGAATATAGTTTTCGTGGTGGAGAAGTTAGAATGCCATTTAATGATATTTTATAT
ATTGAAACGACAGGTTCTTCTCATAAATTAAGAATTGTAGGTAAAAACTTTTTTAAAGAATTTTATGGTACTATTGCAGA
TATTCAAGAAAAAGACAAGGAGACACAGCGTTTCTTTTCACCTCATAAATCTTATTTAGTTAATATTGGAAATATTAAGA
GTTATGACAAAAAAATGAAAGAAATTATTTTTTATGAAGATCACCGTTGCCCAATTACTCGAATGAAAATTGGAAAGTTG
AAAACTATTTTAGAGGAGTCAAAAGGATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-121)

• LytTr DNA-binding domain (LytTR) (152-244)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Streptococcus mitis NCTC 12261	71.429	98.394	0.703
comE/comE2	Streptococcus gordonii strain NCTC7865	71.311	97.992	0.699
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	71.311	97.992	0.699
comE	Streptococcus mitis SK321	70.612	98.394	0.695
comE	Streptococcus pneumoniae TIGR4	70.204	98.394	0.691
comE	Streptococcus pneumoniae Rx1	70.204	98.394	0.691
comE	Streptococcus infantis strain Atu-4	70.204	98.394	0.691
comE	Streptococcus pneumoniae D39	70.204	98.394	0.691
comE	Streptococcus pneumoniae R6	70.204	98.394	0.691
comE/blpR	Streptococcus mutans UA159	40.161	100	0.402
comE/comE2	Streptococcus equinus JB1	35.409	100	0.365