Detailed information NTG0051908

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SCIM_RS09495
• Genome accession: NC_018073
• Coordinates: 1931373..1932563 (+)
• Length: 396 a.a.
• NCBI ID: WP_003075586.1
• Uniprot ID: -
• Organism: Streptococcus intermedius JTH08
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1926373..1937563

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCIM_RS09470 (SCIM_1703)	comE	1928176..1928925 (-)	750	WP_003075577.1	competence system response regulator transcription factor ComE	Regulator
SCIM_RS09475 (SCIM_1704)	comD/comD1	1928925..1930250 (-)	1326	WP_014829844.1	GHKL domain-containing protein	Regulator
SCIM_RS09775	-	1930267..1930413 (-)	147	WP_003075491.1	bacteriocin	-
SCIM_RS09490 (SCIM_1705)	rlmH	1930690..1931169 (-)	480	WP_003075603.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SCIM_RS09495 (SCIM_1706)	htrA	1931373..1932563 (+)	1191	WP_003075586.1	S1C family serine protease	Regulator
SCIM_RS09500 (SCIM_1707)	spo0J	1932618..1933385 (+)	768	WP_003075591.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 41833.90 Da
• Isoelectric Point: 10.0879

>NTDB_id=51908 SCIM_RS09495 WP_003075586.1 1931373..1932563(+) (htrA) [Streptococcus intermedius JTH08]
MKNSSNFTQKFLWLFMVLAIGFIGGLLGNVTSSKLNKNNTTTTKVNHVTTSYKNTNSTTQAVNKVKDAVVSVITYANNKS
QNSIFGNDDFNSNNNNSQRVASEGSGVIYKKDSKYAYLVTNTHVINGASKVDIRLADGNKVPGEIVGSDTYSDISVVRIS
ASKVKSVAEFGDSSKLTVGETAIAIGSPLGSNYANTVTQGIISSLNRNVSLKSEDGQTISTQAIQTDTAINPGNSGGPLV
NIQGQVIGITSSKIASNRGTSVEGLGFAIPSNDVTNIISQLESNGAVTRPALGIQMIDISNLSSSDLSRLKLPAKVTAGV
VVRSAQSGMPAAGKLQKYDVITKIDGKDISSANDLQSALYKHSIGDDIKITFYRNGKETTTTIKLTKSTKDLNSNN

Nucleotide

• Length: 1191 bp

>NTDB_id=51908 SCIM_RS09495 WP_003075586.1 1931373..1932563(+) (htrA) [Streptococcus intermedius JTH08]
ATGAAAAACTCTTCAAATTTCACACAAAAATTCTTATGGCTTTTCATGGTCTTAGCTATAGGTTTTATTGGTGGTTTATT
AGGAAATGTAACTTCTTCAAAATTAAATAAAAACAACACAACTACTACTAAGGTTAACCATGTTACTACATCTTATAAAA
ATACCAATTCTACAACACAGGCTGTCAATAAAGTAAAGGATGCTGTTGTTTCTGTTATTACCTATGCTAATAATAAATCT
CAAAATAGCATTTTTGGAAATGATGACTTTAATAGTAACAATAATAACTCACAAAGAGTAGCAAGCGAAGGTTCAGGGGT
TATTTATAAAAAAGACAGTAAGTATGCCTATCTTGTAACTAATACTCATGTTATTAATGGTGCTAGTAAAGTGGATATTC
GTTTAGCGGATGGTAACAAAGTTCCAGGAGAAATCGTAGGCTCAGATACTTACTCAGATATTTCTGTCGTCCGTATTAGT
GCGAGCAAAGTCAAGTCAGTTGCTGAATTTGGTGATTCTAGTAAATTAACTGTTGGAGAAACTGCTATTGCTATTGGTAG
CCCACTTGGATCAAATTATGCAAATACTGTTACTCAAGGAATTATTTCTAGCTTAAATCGTAATGTGTCTTTAAAATCTG
AAGATGGTCAAACTATCTCTACTCAGGCTATTCAAACAGATACAGCGATTAATCCTGGGAATTCTGGTGGTCCACTTGTA
AATATCCAAGGGCAAGTTATTGGTATTACTTCAAGTAAAATTGCTAGTAATCGTGGAACATCTGTAGAGGGATTAGGTTT
TGCTATTCCATCTAATGATGTCACCAACATCATCAGCCAATTGGAATCAAACGGAGCAGTTACGCGACCAGCTTTAGGAA
TTCAAATGATTGATATTAGTAATCTATCTAGTTCTGATTTATCACGTTTGAAACTTCCAGCAAAAGTGACTGCAGGAGTT
GTTGTTCGTTCAGCTCAGTCTGGAATGCCTGCAGCAGGAAAACTTCAAAAATATGATGTTATTACAAAGATAGATGGAAA
AGACATTTCCTCAGCAAATGATTTACAATCTGCTTTATACAAACATTCAATTGGTGATGATATAAAAATTACATTTTATC
GTAATGGAAAAGAAACAACCACCACCATTAAACTTACAAAATCTACAAAAGATTTAAATTCAAATAATTGA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (290-385)

• Trypsin-like peptidase domain (Trypsin_2) (104-249)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	74.194	100	0.755
htrA	Streptococcus mitis NCTC 12261	71.285	100	0.715
htrA	Streptococcus pneumoniae D39	71.033	100	0.712
htrA	Streptococcus pneumoniae TIGR4	71.033	100	0.712
htrA	Streptococcus pneumoniae R6	71.033	100	0.712
htrA	Streptococcus pneumoniae Rx1	71.033	100	0.712
htrA	Streptococcus mutans UA159	57.033	98.737	0.563