Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   SCIM_RS09475 Genome accession   NC_018073
Coordinates   1928925..1930250 (-) Length   441 a.a.
NCBI ID   WP_014829844.1    Uniprot ID   -
Organism   Streptococcus intermedius JTH08     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1923925..1935250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS09455 (SCIM_1702) - 1925276..1927852 (+) 2577 WP_003077344.1 YfhO family protein -
  SCIM_RS09470 (SCIM_1703) comE 1928176..1928925 (-) 750 WP_003075577.1 competence system response regulator transcription factor ComE Regulator
  SCIM_RS09475 (SCIM_1704) comD/comD1 1928925..1930250 (-) 1326 WP_014829844.1 GHKL domain-containing protein Regulator
  SCIM_RS09775 - 1930267..1930413 (-) 147 WP_003075491.1 bacteriocin -
  SCIM_RS09490 (SCIM_1705) rlmH 1930690..1931169 (-) 480 WP_003075603.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SCIM_RS09495 (SCIM_1706) htrA 1931373..1932563 (+) 1191 WP_003075586.1 S1C family serine protease Regulator
  SCIM_RS09500 (SCIM_1707) spo0J 1932618..1933385 (+) 768 WP_003075591.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51890.78 Da        Isoelectric Point: 8.7063

>NTDB_id=51907 SCIM_RS09475 WP_014829844.1 1928925..1930250(-) (comD/comD1) [Streptococcus intermedius JTH08]
MVKIEFIYWVIFSIIEAISVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTIIHYSVRYIMFFIQPLFFYLYFVKVKKV
KKHSSLFLALFLSLAVSGSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKIDFKENIVQ
LNFYLLFIHLLLNISHWLSNMKNLNSFSSMIATICFLMFMSILFYLQSIREKYEKEEQIKQKEQEQLQLQKYTDEIVNLY
NEIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIEL
IFEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTLNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGV
GRGLGLSNIKEIINNYEGIILDTKIEDEYFIQAMRVRKEGL

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=51907 SCIM_RS09475 WP_014829844.1 1928925..1930250(-) (comD/comD1) [Streptococcus intermedius JTH08]
ATGGTGAAAATAGAATTTATATATTGGGTTATATTCTCCATTATAGAAGCTATTTCTGTTGTATATTGTTATAAGAAGAT
AAGTAGAGTGAATAAAGTGAATATTCACTTTACTTTATTATGTTTAGGAATTGTATTTTTGACTGATTTTACTACAATAA
TACATTATTCGGTTAGATATATAATGTTTTTTATTCAACCATTATTTTTTTATTTATACTTTGTTAAAGTAAAAAAAGTT
AAAAAACATTCGTCTTTATTTTTAGCACTATTTTTATCTTTAGCTGTATCAGGTTCTGAAACCTTCTTTTCAGTTATTAT
TTCTTCTGTTACAGGTGATAAGTTTGTTGATAGATATTGGGGATTGTTCTATATTTTTATTAATATTATTTCTTTAGTTT
TCATTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGATAGATTTTAAAGAAAATATTGTACAA
TTAAATTTTTATCTATTATTTATTCATCTTTTATTAAATATATCGCATTGGCTTAGTAACATGAAAAATTTAAATAGTTT
TTCTAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAATTTTGTTCTACTTACAATCTATTCGCGAAAAATATG
AAAAAGAAGAACAAATTAAGCAAAAAGAACAGGAGCAACTGCAATTACAAAAATATACAGATGAAATTGTTAATCTGTAT
AATGAAATTCGAGGTTTTCGTCATGATTATGGTGGGATGTTGGCAAGTTTTCAATCAGCTATTCATACAGGTGATATAAA
AGAAGTGGAGCGAATCTATCAGGAGGTTCTCGTAAATGCTAATTTACAGCTTCGTTCTGATAAATATACGTATTTTGATT
TAAATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACGCAAACATTGTTTAAGGCACGAGATTACAATATAGAATTA
ATATTTGAAGTAAAAGATTTTGTTAAACCTTTGCCAATTAAATTGTTAGATTTGGTTAGAATGACAAGTGTCCTTTTAAA
TAATGCAATAGAGGGAGCGGCAGAAAGTTATCAAAAAACGCTGAATGTTTCTTTAGTAGATCTGGATACAGAAACGATCT
TAGTTATTCAAAATTCACGTAAGAAAAGACCTCTAGATTTGGAAGAAATTTACCAAACTGATTTTTCAACAAAGGGTGTG
GGACGCGGTTTAGGTTTAAGTAATATTAAAGAAATTATTAATAACTATGAAGGAATTATTCTGGATACTAAAATCGAAGA
TGAATATTTTATACAAGCAATGAGAGTAAGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.566

99.32

0.542
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.072

100

0.542
  comD Streptococcus mitis SK321

46.429

88.889

0.413
  comD Streptococcus mitis NCTC 12261

47.872

85.261

0.408
  comD/comD2 Streptococcus pneumoniae TIGR4

47.34

85.261

0.404
  comD/comD1 Streptococcus pneumoniae Rx1

46.809

85.261

0.399
  comD/comD1 Streptococcus pneumoniae D39

46.809

85.261

0.399
  comD/comD1 Streptococcus pneumoniae R6

46.809

85.261

0.399

Multiple sequence alignment