Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   JDY60_RS07300 Genome accession   NZ_CP066172
Coordinates   1533072..1534013 (-) Length   313 a.a.
NCBI ID   WP_000249575.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1528072..1539013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JDY60_RS07260 (JDY60_07260) comYH 1528671..1529624 (-) 954 WP_049490205.1 class I SAM-dependent methyltransferase Machinery gene
  JDY60_RS07265 (JDY60_07265) - 1529683..1530273 (-) 591 WP_049490204.1 class I SAM-dependent methyltransferase -
  JDY60_RS07270 (JDY60_07270) comGG/cglG 1530306..1530719 (-) 414 WP_070568123.1 competence type IV pilus minor pilin ComGG Machinery gene
  JDY60_RS07275 (JDY60_07275) comGF/cglF 1530697..1531158 (-) 462 WP_070568120.1 competence type IV pilus minor pilin ComGF Machinery gene
  JDY60_RS07280 (JDY60_07280) comGE/cglE 1531121..1531423 (-) 303 WP_200370534.1 competence type IV pilus minor pilin ComGE Machinery gene
  JDY60_RS07285 (JDY60_07285) comGD/cglD 1531386..1531820 (-) 435 WP_200370535.1 competence type IV pilus minor pilin ComGD Machinery gene
  JDY60_RS07290 (JDY60_07290) comGC/cglC 1531783..1532106 (-) 324 WP_200370536.1 competence type IV pilus major pilin ComGC Machinery gene
  JDY60_RS07295 (JDY60_07295) comGB/cglB 1532108..1533124 (-) 1017 WP_000355379.1 competence type IV pilus assembly protein ComGB Machinery gene
  JDY60_RS07300 (JDY60_07300) comGA/cglA/cilD 1533072..1534013 (-) 942 WP_000249575.1 competence type IV pilus ATPase ComGA Machinery gene
  JDY60_RS07305 (JDY60_07305) - 1534083..1534448 (-) 366 WP_000286396.1 DUF1033 family protein -
  JDY60_RS07310 (JDY60_07310) nagA 1534603..1535754 (-) 1152 WP_001134447.1 N-acetylglucosamine-6-phosphate deacetylase -
  JDY60_RS07315 (JDY60_07315) - 1535895..1537712 (-) 1818 WP_084855890.1 acyltransferase family protein -
  JDY60_RS07320 (JDY60_07320) tgt 1537846..1538988 (-) 1143 WP_001285238.1 tRNA guanosine(34) transglycosylase Tgt -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35475.45 Da        Isoelectric Point: 5.7829

>NTDB_id=518078 JDY60_RS07300 WP_000249575.1 1533072..1534013(-) (comGA/cglA/cilD) [Streptococcus oralis strain SF100]
MVQEIAQKIIATAKAKKAQDIYFIPKEKSYELHMRVGDARCLVDSYEFDVLAAVISHFKFVAGMNVGEKRRSQLGSCDYQ
HGEKVSSLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDMNELGEQYRQRGLYLFAGPVGSGKTTLMHELAKSLFMGQQ
VMSIEDPVEIKQEDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVTEEELAVVLQGVCYQRLIGGGGIVDFANKDYQEHQPTRWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=518078 JDY60_RS07300 WP_000249575.1 1533072..1534013(-) (comGA/cglA/cilD) [Streptococcus oralis strain SF100]
ATGGTACAAGAAATTGCACAGAAAATTATTGCTACTGCGAAAGCAAAGAAGGCTCAGGATATCTATTTCATTCCCAAGGA
AAAGTCCTATGAGCTTCACATGCGGGTTGGAGACGCGCGGTGTCTCGTTGACTCCTATGAGTTTGATGTTTTAGCTGCTG
TGATTAGTCATTTTAAGTTTGTAGCGGGTATGAATGTAGGGGAGAAGAGACGTAGTCAGCTGGGCTCTTGCGACTATCAG
CATGGGGAGAAGGTGTCTTCTCTGCGTTTGTCTACCGTAGGAGATTATCGGGGACATGAGAGTTTGGTCATTCGTTTGTT
GCACGACGAAGAGCAGGACCTGCATTTCTGGTTTCAGGATATGAATGAACTGGGTGAGCAGTACCGGCAACGGGGCCTCT
ACCTTTTTGCGGGTCCAGTTGGAAGTGGCAAGACGACCTTGATGCACGAATTAGCCAAGTCTCTGTTTATGGGGCAACAG
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGAAGACATGCTCCAGTTGCAGTTGAATGAAGCGATTGGCTTGAC
CTATGAAAATCTGATCAAACTGTCTCTCCGGCATCGTCCGGACCTCTTGATTATCGGTGAAATTCGTGACAGCGAGACAG
CGCGTGCAGTGGTCAGAGCCAGTTTGACAGGGGCGACAGTCTTTTCAACCATTCATGCTAAGAGTATCCGAGGTGTTTAT
GAACGCCTTCTGGAGTTGGGGGTGACGGAGGAGGAATTAGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAAAGACTATCAAGAACACCAGCCAACCAGGTGGAATGAACAGATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCCGAAACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

88.818

100

0.888
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

88.179

100

0.882
  comGA/cglA/cilD Streptococcus pneumoniae D39

88.179

100

0.882
  comGA/cglA/cilD Streptococcus pneumoniae R6

88.179

100

0.882
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

88.179

100

0.882
  comYA Streptococcus gordonii str. Challis substr. CH1

77.419

99.042

0.767
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.323

99.042

0.597
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

44.231

83.067

0.367