Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   I6H76_RS05120 Genome accession   NZ_CP065994
Coordinates   1012881..1013822 (-) Length   313 a.a.
NCBI ID   WP_043878331.1    Uniprot ID   -
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1007881..1018822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS05080 (I6H76_05080) - 1007953..1009152 (-) 1200 WP_006531742.1 acetate kinase -
  I6H76_RS05085 (I6H76_05085) comYH 1009206..1010162 (-) 957 WP_006531743.1 class I SAM-dependent methyltransferase Machinery gene
  I6H76_RS05090 (I6H76_05090) comGG 1010216..1010566 (-) 351 WP_043878322.1 competence type IV pilus minor pilin ComGG -
  I6H76_RS05095 (I6H76_05095) comYF 1010538..1010975 (-) 438 WP_006531745.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6H76_RS05100 (I6H76_05100) comYE 1010959..1011252 (-) 294 WP_006531746.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6H76_RS05105 (I6H76_05105) comYD 1011206..1011637 (-) 432 WP_006531747.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6H76_RS05110 (I6H76_05110) comGC/cglC 1011621..1011914 (-) 294 WP_006531748.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H76_RS05115 (I6H76_05115) comYB 1011914..1012957 (-) 1044 WP_174221225.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H76_RS05120 (I6H76_05120) comYA 1012881..1013822 (-) 942 WP_043878331.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H76_RS05125 (I6H76_05125) - 1013935..1014264 (-) 330 WP_006531751.1 DUF1033 family protein -
  I6H76_RS05130 (I6H76_05130) rpoC 1014420..1018058 (-) 3639 WP_043878324.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35617.68 Da        Isoelectric Point: 5.1694

>NTDB_id=516135 I6H76_RS05120 WP_043878331.1 1012881..1013822(-) (comYA) [Streptococcus infantarius strain FDAARGOS_1019]
MIQEKAKQLIKDAVEKNAQDIYIVPKKEHYEIYQSVGDERQFIQELASDEMTSVISHFKFVAGMNVGEKRRSQLGSCDYE
FAEGEEISLRLSTVGDYRGRESLVIRLLYSGRHDLQYWFDGMKNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPDK
QVITIEDPVEIKQDNMLQLQLNDEIGMTYDNLIKLSLRHRPDILIIGEIRDSETARAVIRASLTGVLVFSTIHAKSIPGV
YARLLELGVSRQELENSLRAIIYQRLIGGGGVVDFAKGDFEQYPPTRWNEQIESLARDGHISLEEAKIEKIAL

Nucleotide


Download         Length: 942 bp        

>NTDB_id=516135 I6H76_RS05120 WP_043878331.1 1012881..1013822(-) (comYA) [Streptococcus infantarius strain FDAARGOS_1019]
ATGATTCAGGAAAAAGCAAAGCAGCTGATCAAGGATGCTGTTGAAAAGAATGCGCAAGATATTTACATTGTTCCTAAGAA
GGAGCACTATGAAATTTATCAAAGTGTTGGTGATGAACGTCAGTTTATTCAGGAACTTGCTAGTGATGAGATGACAAGTG
TGATTAGTCACTTTAAATTTGTGGCTGGGATGAATGTTGGTGAGAAACGTCGTAGTCAGCTAGGCTCTTGTGATTATGAA
TTTGCTGAGGGTGAAGAGATTTCACTGCGTTTATCCACTGTTGGAGATTATCGAGGGCGTGAGAGCCTGGTCATTAGACT
TCTTTATTCAGGACGTCATGATTTGCAATATTGGTTTGATGGGATGAAGAATATTTTAGAGGCGATTGATAGTCGAGGTC
TTTATCTTTTTTCCGGGCCGGTAGGGAGTGGAAAGACCACTCTCATGTATCAATTGGTTCGTGAAAAGTTCCCTGATAAG
CAGGTCATTACGATAGAAGACCCTGTTGAGATTAAGCAGGACAATATGTTGCAGCTGCAACTTAATGATGAGATTGGCAT
GACTTATGATAATCTTATCAAGCTCTCGCTTCGTCATAGACCTGATATTTTGATTATTGGTGAGATTCGTGATAGTGAGA
CAGCGCGTGCGGTTATTAGAGCTAGTCTGACAGGTGTGCTCGTCTTTTCAACCATTCATGCAAAAAGTATTCCAGGTGTT
TATGCTAGGTTATTAGAACTGGGTGTTAGTAGGCAAGAACTTGAAAATAGTTTACGAGCTATCATTTATCAGCGATTAAT
TGGCGGTGGAGGTGTTGTGGATTTTGCTAAAGGAGATTTTGAACAGTATCCCCCAACAAGGTGGAATGAGCAAATTGAAA
GCCTTGCTAGGGACGGACATATTAGCCTTGAGGAAGCAAAAATCGAAAAAATTGCCCTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

70.74

99.361

0.703
  comYA Streptococcus mutans UA140

70.418

99.361

0.7
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

67.097

99.042

0.665
  comYA Streptococcus gordonii str. Challis substr. CH1

65.273

99.361

0.649
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.744

99.681

0.645
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.782

99.681

0.636
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.782

99.681

0.636
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.782

99.681

0.636
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.782

99.681

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

54.603

100

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

43.066

87.54

0.377