Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   I6H76_RS05085 Genome accession   NZ_CP065994
Coordinates   1009206..1010162 (-) Length   318 a.a.
NCBI ID   WP_006531743.1    Uniprot ID   A0A380KLA4
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1004206..1015162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS05050 (I6H76_05050) pepA 1004341..1005408 (+) 1068 WP_006531736.1 glutamyl aminopeptidase -
  I6H76_RS05055 (I6H76_05055) proC 1005470..1006240 (+) 771 WP_006531737.1 pyrroline-5-carboxylate reductase -
  I6H76_RS05060 (I6H76_05060) - 1006275..1006910 (-) 636 WP_014334210.1 CPBP family intramembrane glutamic endopeptidase -
  I6H76_RS05065 (I6H76_05065) - 1006925..1007380 (-) 456 WP_006531739.1 hypothetical protein -
  I6H76_RS05070 (I6H76_05070) - 1007381..1007581 (-) 201 WP_006531740.1 hypothetical protein -
  I6H76_RS05075 (I6H76_05075) - 1007597..1007794 (-) 198 WP_006531741.1 helix-turn-helix transcriptional regulator -
  I6H76_RS05080 (I6H76_05080) - 1007953..1009152 (-) 1200 WP_006531742.1 acetate kinase -
  I6H76_RS05085 (I6H76_05085) comYH 1009206..1010162 (-) 957 WP_006531743.1 class I SAM-dependent methyltransferase Machinery gene
  I6H76_RS05090 (I6H76_05090) comGG 1010216..1010566 (-) 351 WP_043878322.1 competence type IV pilus minor pilin ComGG -
  I6H76_RS05095 (I6H76_05095) comYF 1010538..1010975 (-) 438 WP_006531745.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6H76_RS05100 (I6H76_05100) comYE 1010959..1011252 (-) 294 WP_006531746.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6H76_RS05105 (I6H76_05105) comYD 1011206..1011637 (-) 432 WP_006531747.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6H76_RS05110 (I6H76_05110) comGC/cglC 1011621..1011914 (-) 294 WP_006531748.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H76_RS05115 (I6H76_05115) comYB 1011914..1012957 (-) 1044 WP_174221225.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H76_RS05120 (I6H76_05120) comYA 1012881..1013822 (-) 942 WP_043878331.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H76_RS05125 (I6H76_05125) - 1013935..1014264 (-) 330 WP_006531751.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35885.95 Da        Isoelectric Point: 4.4551

>NTDB_id=516129 I6H76_RS05085 WP_006531743.1 1009206..1010162(-) (comYH) [Streptococcus infantarius strain FDAARGOS_1019]
MNFEKIETAYGLILENIQLIENELKTHIYDALIEQNSFYLGAEGANETVAANNEKLRQLDLTKEEWRRAFQFIFIKAAQT
EALQANHQFTPDAIGFILMFLIENLTASKELDVLEIGSGTGNLAQTLLNNSSKDLNYLGIEVDDLLIDLSASIAEVMDSK
AQFIQEDAVRPQILKESDVIISDLPVGFYPNDEIAKRYKVASSDEHTYAHHLLMEQSLKYLKKDGIAVFLAPVSLLTSKQ
SDLLKAWLKDYADVIAVITLPESIFGNAANAKSIFVLKKQAEHTPETFVYPLADLQSREALTDFIEKFKKWNVENMIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=516129 I6H76_RS05085 WP_006531743.1 1009206..1010162(-) (comYH) [Streptococcus infantarius strain FDAARGOS_1019]
ATGAATTTTGAAAAAATCGAAACAGCTTATGGGCTGATTCTAGAAAATATACAGTTAATCGAAAATGAGTTGAAAACACA
CATTTACGATGCACTTATTGAACAAAACTCTTTTTATCTTGGTGCTGAAGGTGCCAATGAGACAGTAGCTGCCAATAATG
AAAAATTACGCCAACTTGATTTAACTAAAGAAGAATGGCGTCGTGCTTTTCAGTTTATTTTCATTAAAGCTGCTCAAACA
GAAGCACTTCAGGCAAACCACCAATTTACACCTGATGCTATTGGCTTTATCTTAATGTTCCTTATTGAGAATTTGACAGC
CTCAAAAGAACTTGATGTTTTAGAAATCGGTAGCGGAACAGGTAACCTTGCACAAACCTTGCTTAATAATTCATCTAAAG
ACTTGAATTACCTTGGAATTGAAGTTGATGATTTGTTGATTGACTTGTCAGCAAGTATTGCCGAAGTGATGGATTCTAAA
GCTCAGTTCATTCAAGAAGATGCTGTGCGCCCACAGATTCTTAAGGAAAGTGACGTCATCATCAGTGACCTTCCAGTCGG
CTTCTATCCAAATGATGAGATTGCAAAACGCTACAAAGTAGCAAGTAGTGATGAACACACTTATGCGCATCATTTATTGA
TGGAACAATCTCTCAAATATCTCAAAAAAGATGGTATTGCTGTCTTTTTAGCACCGGTTAGTCTTTTGACTAGTAAACAA
AGTGATTTGTTAAAGGCATGGTTGAAGGATTACGCTGATGTTATTGCGGTGATTACTTTACCAGAATCTATTTTCGGCAA
TGCGGCCAATGCTAAGTCAATTTTTGTCTTGAAGAAACAGGCTGAACATACTCCAGAAACATTTGTTTACCCGCTTGCTG
ACTTGCAAAGTCGCGAAGCTTTAACAGATTTTATTGAGAAATTTAAAAAATGGAATGTTGAAAATATGATTTTTTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380KLA4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

68.038

99.371

0.676
  comYH Streptococcus mutans UA159

67.722

99.371

0.673