Detailed information
Bioinformatically predicted
Overview
| Name | comE/blpR | Type | Regulator |
| Locus tag | SMULJ23_RS01390 | Genome accession | NC_017768 |
| Coordinates | 308707..309459 (+) | Length | 250 a.a. |
| NCBI ID | WP_002262114.1 | Uniprot ID | Q8DS93 |
| Organism | Streptococcus mutans LJ23 | ||
| Function | activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation |
||
Genomic Context
Location: 303707..314459
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SMULJ23_RS01370 (SMULJ23_0255) | dnaI | 304626..305525 (+) | 900 | WP_002265451.1 | primosomal protein DnaI | - |
| SMULJ23_RS01375 (SMULJ23_0256) | der | 305538..306848 (+) | 1311 | WP_002292004.1 | ribosome biogenesis GTPase Der | - |
| SMULJ23_RS01380 (SMULJ23_0257) | - | 306923..307549 (+) | 627 | WP_014677755.1 | hypothetical protein | - |
| SMULJ23_RS01385 (SMULJ23_0258) | - | 307597..308235 (+) | 639 | WP_002292006.1 | VTT domain-containing protein | - |
| SMULJ23_RS01390 (SMULJ23_0259) | comE/blpR | 308707..309459 (+) | 753 | WP_002262114.1 | response regulator transcription factor | Regulator |
| SMULJ23_RS01395 (SMULJ23_0260) | comD/blpH | 309456..310781 (+) | 1326 | WP_002292008.1 | GHKL domain-containing protein | Regulator |
| SMULJ23_RS01400 (SMULJ23_0261) | comC/blpC | 310923..311063 (-) | 141 | WP_002270250.1 | ComC/BlpC family leader-containing pheromone/bacteriocin | Regulator |
| SMULJ23_RS01405 (SMULJ23_0262) | cipB | 311330..311560 (+) | 231 | WP_002265368.1 | Blp family class II bacteriocin | Regulator |
| SMULJ23_RS01410 (SMULJ23_0263) | - | 311691..312092 (+) | 402 | WP_002310604.1 | hypothetical protein | - |
| SMULJ23_RS01415 (SMULJ23_0265) | - | 313473..313886 (+) | 414 | Protein_260 | hypothetical protein | - |
| SMULJ23_RS01420 (SMULJ23_0266) | - | 314038..314442 (+) | 405 | WP_002263912.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 250 a.a. Molecular weight: 29358.71 Da Isoelectric Point: 8.2551
>NTDB_id=50740 SMULJ23_RS01390 WP_002262114.1 308707..309459(+) (comE/blpR) [Streptococcus mutans LJ23]
MISIFVLEDDFLQQGRLETTIAAIMKEKNWSYKELTIFGKPQQLIDAIPEKGNHQIFFLDIEIKKEEKKGLEVANQIRQH
NPSAVIVFVTTHSEFMPLTFQYQVSALDFIDKSLNPEEFSHRIESALYYAMENSQKNGQSEELFIFHSSETQFQVPFAEI
LYFETSSTAHKLCLYTYDERIEFYGSMTDIVKMDKRLFQCHRSFIVNPANITRIDRKKRLAYFRNNKSCLISRTKLTKLR
AVIADQRRAK
MISIFVLEDDFLQQGRLETTIAAIMKEKNWSYKELTIFGKPQQLIDAIPEKGNHQIFFLDIEIKKEEKKGLEVANQIRQH
NPSAVIVFVTTHSEFMPLTFQYQVSALDFIDKSLNPEEFSHRIESALYYAMENSQKNGQSEELFIFHSSETQFQVPFAEI
LYFETSSTAHKLCLYTYDERIEFYGSMTDIVKMDKRLFQCHRSFIVNPANITRIDRKKRLAYFRNNKSCLISRTKLTKLR
AVIADQRRAK
Nucleotide
Download Length: 753 bp
>NTDB_id=50740 SMULJ23_RS01390 WP_002262114.1 308707..309459(+) (comE/blpR) [Streptococcus mutans LJ23]
ATGATTTCTATTTTTGTATTGGAAGATGATTTTTTACAACAAGGACGTCTTGAAACCACCATTGCAGCTATCATGAAAGA
AAAAAATTGGTCTTATAAAGAATTGACTATTTTTGGAAAACCACAACAACTTATTGACGCTATCCCTGAAAAGGGCAATC
ACCAGATTTTCTTTTTGGATATTGAAATCAAAAAAGAGGAAAAGAAAGGACTGGAAGTAGCCAATCAGATTAGACAGCAT
AATCCTAGTGCAGTTATTGTCTTTGTCACGACACATTCTGAGTTTATGCCCCTCACTTTTCAGTATCAGGTATCTGCTTT
GGATTTTATTGATAAATCTTTGAATCCTGAGGAGTTCTCCCACCGCATTGAATCAGCGCTGTATTATGCTATGGAAAACA
GCCAGAAGAATGGTCAATCAGAGGAACTTTTTATTTTCCATTCATCTGAAACTCAGTTTCAGGTCCCTTTTGCTGAGATT
CTGTATTTTGAAACATCTTCAACAGCCCATAAGCTCTGCCTTTATACTTATGATGAACGGATTGAATTCTACGGCAGTAT
GACTGACATTGTTAAAATGGATAAGAGACTTTTTCAGTGCCATCGCTCTTTTATTGTCAATCCTGCCAATATTACCCGTA
TTGATCGGAAAAAACGCTTGGCCTATTTTCGAAATAATAAGTCTTGTCTTATTTCACGAACTAAGTTAACAAAACTGAGA
GCTGTGATTGCTGATCAAAGGAGAGCAAAATGA
ATGATTTCTATTTTTGTATTGGAAGATGATTTTTTACAACAAGGACGTCTTGAAACCACCATTGCAGCTATCATGAAAGA
AAAAAATTGGTCTTATAAAGAATTGACTATTTTTGGAAAACCACAACAACTTATTGACGCTATCCCTGAAAAGGGCAATC
ACCAGATTTTCTTTTTGGATATTGAAATCAAAAAAGAGGAAAAGAAAGGACTGGAAGTAGCCAATCAGATTAGACAGCAT
AATCCTAGTGCAGTTATTGTCTTTGTCACGACACATTCTGAGTTTATGCCCCTCACTTTTCAGTATCAGGTATCTGCTTT
GGATTTTATTGATAAATCTTTGAATCCTGAGGAGTTCTCCCACCGCATTGAATCAGCGCTGTATTATGCTATGGAAAACA
GCCAGAAGAATGGTCAATCAGAGGAACTTTTTATTTTCCATTCATCTGAAACTCAGTTTCAGGTCCCTTTTGCTGAGATT
CTGTATTTTGAAACATCTTCAACAGCCCATAAGCTCTGCCTTTATACTTATGATGAACGGATTGAATTCTACGGCAGTAT
GACTGACATTGTTAAAATGGATAAGAGACTTTTTCAGTGCCATCGCTCTTTTATTGTCAATCCTGCCAATATTACCCGTA
TTGATCGGAAAAAACGCTTGGCCTATTTTCGAAATAATAAGTCTTGTCTTATTTCACGAACTAAGTTAACAAAACTGAGA
GCTGTGATTGCTGATCAAAGGAGAGCAAAATGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comE/blpR | Streptococcus mutans UA159 |
100 |
100 |
1 |
| comE/comE1 | Streptococcus equinus JB1 |
46.888 |
96.4 |
0.452 |
| comE | Streptococcus mitis NCTC 12261 |
41.7 |
98.8 |
0.412 |
| comE | Streptococcus infantis strain Atu-4 |
41.7 |
98.8 |
0.412 |
| comE | Streptococcus pneumoniae D39 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus pneumoniae Rx1 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus pneumoniae R6 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus pneumoniae TIGR4 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus mitis SK321 |
41.296 |
98.8 |
0.408 |
| comE/comE2 | Streptococcus equinus JB1 |
40.664 |
96.4 |
0.392 |
| comE/comE1 | Streptococcus gordonii str. Challis substr. CH1 |
37.551 |
98 |
0.368 |
| comE/comE2 | Streptococcus gordonii strain NCTC7865 |
37.551 |
98 |
0.368 |