Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   SMULJ23_RS01395 Genome accession   NC_017768
Coordinates   309456..310781 (+) Length   441 a.a.
NCBI ID   WP_002292008.1    Uniprot ID   -
Organism   Streptococcus mutans LJ23     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 304456..315781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMULJ23_RS01370 (SMULJ23_0255) dnaI 304626..305525 (+) 900 WP_002265451.1 primosomal protein DnaI -
  SMULJ23_RS01375 (SMULJ23_0256) der 305538..306848 (+) 1311 WP_002292004.1 ribosome biogenesis GTPase Der -
  SMULJ23_RS01380 (SMULJ23_0257) - 306923..307549 (+) 627 WP_014677755.1 hypothetical protein -
  SMULJ23_RS01385 (SMULJ23_0258) - 307597..308235 (+) 639 WP_002292006.1 VTT domain-containing protein -
  SMULJ23_RS01390 (SMULJ23_0259) comE/blpR 308707..309459 (+) 753 WP_002262114.1 response regulator transcription factor Regulator
  SMULJ23_RS01395 (SMULJ23_0260) comD/blpH 309456..310781 (+) 1326 WP_002292008.1 GHKL domain-containing protein Regulator
  SMULJ23_RS01400 (SMULJ23_0261) comC/blpC 310923..311063 (-) 141 WP_002270250.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  SMULJ23_RS01405 (SMULJ23_0262) cipB 311330..311560 (+) 231 WP_002265368.1 Blp family class II bacteriocin Regulator
  SMULJ23_RS01410 (SMULJ23_0263) - 311691..312092 (+) 402 WP_002310604.1 hypothetical protein -
  SMULJ23_RS01415 (SMULJ23_0265) - 313473..313886 (+) 414 Protein_260 hypothetical protein -
  SMULJ23_RS01420 (SMULJ23_0266) - 314038..314442 (+) 405 WP_002263912.1 hypothetical protein -
  SMULJ23_RS10710 - 314565..314777 (-) 213 Protein_262 IS3 family transposase -
  SMULJ23_RS10590 (SMULJ23_0268) - 315217..315381 (+) 165 WP_002265308.1 hypothetical protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50441.61 Da        Isoelectric Point: 9.8776

>NTDB_id=50741 SMULJ23_RS01395 WP_002292008.1 309456..310781(+) (comD/blpH) [Streptococcus mutans LJ23]
MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIALSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGTQGIVMGSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQVLYVIESYNVIPTLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSSKIQLPGMELLDFITILSILCDNAIEAAFESLNPEIQLAFFKKNGSIVFIIQNSTKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSSHHHLFKQLLIIK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=50741 SMULJ23_RS01395 WP_002292008.1 309456..310781(+) (comD/blpH) [Streptococcus mutans LJ23]
ATGAATGAAGCCTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCTAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTGAACGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGCTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAACTCAAGGAATTGTAATGGGCAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTCAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATTCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGTATTGTATGTTATAGAGAGTTATAATGTGATACC
GACTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAAATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATTCAAAACGATGCTGTCAAGGGTATCTTGTCAGCAAAAATCTTAGAAGCTCAGAATAAA
AAGATTGCTGTCAATGTAGAAGTCTCAAGTAAAATACAACTGCCTGGGATGGAGTTGCTTGATTTCATTACTATACTTTC
TATCTTGTGTGATAATGCCATTGAGGCTGCTTTCGAATCATTAAATCCTGAAATTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGCATAGTCTTTATCATTCAGAATTCCACCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTTACAAAC
AAGCAGTCATCATCATTTATTCAAGCAACTCCTAATAATAAAATAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

99.546

100

0.995

Multiple sequence alignment