Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/blpC   Type   Regulator
Locus tag   SMULJ23_RS01400 Genome accession   NC_017768
Coordinates   310923..311063 (-) Length   46 a.a.
NCBI ID   WP_002270250.1    Uniprot ID   Q9APK7
Organism   Streptococcus mutans LJ23     
Function   binding to ComD; induce autophosphorylation of ComD; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context


Location: 305923..316063
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMULJ23_RS01380 (SMULJ23_0257) - 306923..307549 (+) 627 WP_014677755.1 hypothetical protein -
  SMULJ23_RS01385 (SMULJ23_0258) - 307597..308235 (+) 639 WP_002292006.1 VTT domain-containing protein -
  SMULJ23_RS01390 (SMULJ23_0259) comE/blpR 308707..309459 (+) 753 WP_002262114.1 response regulator transcription factor Regulator
  SMULJ23_RS01395 (SMULJ23_0260) comD/blpH 309456..310781 (+) 1326 WP_002292008.1 GHKL domain-containing protein Regulator
  SMULJ23_RS01400 (SMULJ23_0261) comC/blpC 310923..311063 (-) 141 WP_002270250.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  SMULJ23_RS01405 (SMULJ23_0262) cipB 311330..311560 (+) 231 WP_002265368.1 Blp family class II bacteriocin Regulator
  SMULJ23_RS01410 (SMULJ23_0263) - 311691..312092 (+) 402 WP_002310604.1 hypothetical protein -
  SMULJ23_RS01415 (SMULJ23_0265) - 313473..313886 (+) 414 Protein_260 hypothetical protein -
  SMULJ23_RS01420 (SMULJ23_0266) - 314038..314442 (+) 405 WP_002263912.1 hypothetical protein -
  SMULJ23_RS10710 - 314565..314777 (-) 213 Protein_262 IS3 family transposase -
  SMULJ23_RS10590 (SMULJ23_0268) - 315217..315381 (+) 165 WP_002265308.1 hypothetical protein -
  SMULJ23_RS01430 (SMULJ23_0271) - 315786..315998 (+) 213 WP_002264173.1 Blp family class II bacteriocin -

Sequence


Protein


Download         Length: 46 a.a.        Molecular weight: 5195.02 Da        Isoelectric Point: 10.4929

>NTDB_id=50742 SMULJ23_RS01400 WP_002270250.1 310923..311063(-) (comC/blpC) [Streptococcus mutans LJ23]
MKKTPSLKNDFKEIKTDELEIIIGGSGSLSTFFRLFNRSFTQALGK

Nucleotide


Download         Length: 141 bp        

>NTDB_id=50742 SMULJ23_RS01400 WP_002270250.1 310923..311063(-) (comC/blpC) [Streptococcus mutans LJ23]
ATGAAAAAAACACCATCATTAAAAAATGACTTTAAAGAAATTAAGACTGATGAATTAGAGATTATCATTGGCGGAAGCGG
AAGCCTATCAACATTTTTCCGGCTGTTTAACAGAAGTTTTACACAAGCTTTGGGAAAATAA

Domains


Predicted by InterproScan.

(1-32)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q9APK7

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/blpC Streptococcus mutans UA159

97.826

100

0.978


Multiple sequence alignment