Detailed information NTG0506519

Bioinformatically predicted

Overview

• Name: comGA/cglA
• Type: Machinery gene
• Locus tag: I2436_RS00700
• Genome accession: NZ_CP065060
• Coordinates: 122327..123265 (+)
• Length: 312 a.a.
• NCBI ID: WP_164437804.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ28
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 117327..128265

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2436_RS00680 (GDAKBCAL_00135)	-	117481..118527 (+)	1047	WP_206153225.1	acyltransferase family protein	-
I2436_RS00685 (GDAKBCAL_00136)	-	118588..118953 (+)	366	WP_043038372.1	DUF1033 family protein	-
I2436_RS00690	-	119498..121500 (+)	2003	Protein_100	DUF1430 domain-containing protein	-
I2436_RS00695 (GDAKBCAL_00139)	-	121502..122170 (+)	669	WP_043052639.1	ATP-binding cassette domain-containing protein	-
I2436_RS00700 (GDAKBCAL_00140)	comGA/cglA	122327..123265 (+)	939	WP_164437804.1	competence type IV pilus ATPase ComGA	Machinery gene
I2436_RS00705 (GDAKBCAL_00141)	comYB	123198..124232 (+)	1035	WP_227687788.1	competence type IV pilus assembly protein ComGB	Machinery gene
I2436_RS00710 (GDAKBCAL_00142)	comGC/cglC	124233..124556 (+)	324	WP_206152868.1	competence type IV pilus major pilin ComGC	Machinery gene
I2436_RS00715 (GDAKBCAL_00143)	comGD	124534..124959 (+)	426	WP_206152869.1	competence type IV pilus minor pilin ComGD	-
I2436_RS00720 (GDAKBCAL_00144)	comGE	124916..125206 (+)	291	WP_014622143.1	competence type IV pilus minor pilin ComGE	-
I2436_RS00725 (GDAKBCAL_00145)	comYF	125193..125627 (+)	435	WP_037580631.1	competence type IV pilus minor pilin ComGF	Machinery gene
I2436_RS00730 (GDAKBCAL_00146)	comGG	125605..125967 (+)	363	WP_012514785.1	competence type IV pilus minor pilin ComGG	-
I2436_RS00735 (GDAKBCAL_00147)	comYH	126029..126982 (+)	954	WP_012514788.1	class I SAM-dependent methyltransferase	Machinery gene
I2436_RS00740 (GDAKBCAL_00148)	-	127042..128244 (+)	1203	WP_012514789.1	acetate kinase	-

Sequence

Protein

• Length: 312 a.a.
• Molecular weight: 35157.34 Da
• Isoelectric Point: 6.6904

>NTDB_id=506519 I2436_RS00700 WP_164437804.1 122327..123265(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MVQELAKRLIRQAEELQAQDIYILPRGASYELLMRIGDDKRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDGTKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQASQWNQQIDQLLAEGHLNTGQARLEKIIQ

Nucleotide

• Length: 939 bp

>NTDB_id=506519 I2436_RS00700 WP_164437804.1 122327..123265(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGGTTCAAGAATTAGCCAAGCGGCTTATCAGGCAGGCCGAAGAATTGCAGGCTCAGGATATTTATATACTGCCAAGAGG
GGCAAGCTATGAGCTTTTGATGAGGATAGGTGATGACAAGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGAGAAAAAAGACGCTGCCAGCTCGGTGCTTGTGACTACGAC
CTTGATGGCACTAAGGTATCTCTACGATTATCAGCTGTGGGTGACTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCCAGAGGCCTTT
ACCTCTTTTCTGGACCGGTTGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATTAAAAATGATCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTTTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATCAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCAAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAGCCAGTGGAATCAGCAGATTGATCAGC
TTCTTGCGGAGGGACATCTCAATACCGGGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (10-264)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	68.387	99.359	0.679
comYA	Streptococcus mutans UA159	63.666	99.679	0.635
comYA	Streptococcus mutans UA140	63.666	99.679	0.635
comYA	Streptococcus gordonii str. Challis substr. CH1	61.29	99.359	0.609
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	61.29	99.359	0.609
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	60.968	99.359	0.606
comGA/cglA/cilD	Streptococcus pneumoniae D39	60.968	99.359	0.606
comGA/cglA/cilD	Streptococcus pneumoniae R6	60.968	99.359	0.606
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	60.968	99.359	0.606
comGA	Lactococcus lactis subsp. cremoris KW2	52.733	99.679	0.526
comGA	Latilactobacillus sakei subsp. sakei 23K	39.322	94.551	0.372