Detailed information NTG0506520

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: I2436_RS00705
• Genome accession: NZ_CP065060
• Coordinates: 123198..124232 (+)
• Length: 344 a.a.
• NCBI ID: WP_227687788.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ28
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 118198..129232

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2436_RS00685 (GDAKBCAL_00136)	-	118588..118953 (+)	366	WP_043038372.1	DUF1033 family protein	-
I2436_RS00690	-	119498..121500 (+)	2003	Protein_100	DUF1430 domain-containing protein	-
I2436_RS00695 (GDAKBCAL_00139)	-	121502..122170 (+)	669	WP_043052639.1	ATP-binding cassette domain-containing protein	-
I2436_RS00700 (GDAKBCAL_00140)	comGA/cglA	122327..123265 (+)	939	WP_164437804.1	competence type IV pilus ATPase ComGA	Machinery gene
I2436_RS00705 (GDAKBCAL_00141)	comYB	123198..124232 (+)	1035	WP_227687788.1	competence type IV pilus assembly protein ComGB	Machinery gene
I2436_RS00710 (GDAKBCAL_00142)	comGC/cglC	124233..124556 (+)	324	WP_206152868.1	competence type IV pilus major pilin ComGC	Machinery gene
I2436_RS00715 (GDAKBCAL_00143)	comGD	124534..124959 (+)	426	WP_206152869.1	competence type IV pilus minor pilin ComGD	-
I2436_RS00720 (GDAKBCAL_00144)	comGE	124916..125206 (+)	291	WP_014622143.1	competence type IV pilus minor pilin ComGE	-
I2436_RS00725 (GDAKBCAL_00145)	comYF	125193..125627 (+)	435	WP_037580631.1	competence type IV pilus minor pilin ComGF	Machinery gene
I2436_RS00730 (GDAKBCAL_00146)	comGG	125605..125967 (+)	363	WP_012514785.1	competence type IV pilus minor pilin ComGG	-
I2436_RS00735 (GDAKBCAL_00147)	comYH	126029..126982 (+)	954	WP_012514788.1	class I SAM-dependent methyltransferase	Machinery gene
I2436_RS00740 (GDAKBCAL_00148)	-	127042..128244 (+)	1203	WP_012514789.1	acetate kinase	-
I2436_RS00745 (GDAKBCAL_00149)	-	128616..129230 (-)	615	WP_021320266.1	hypothetical protein	-

Sequence

Protein

• Length: 344 a.a.
• Molecular weight: 39440.70 Da
• Isoelectric Point: 9.4360

>NTDB_id=506520 I2436_RS00705 WP_227687788.1 123198..124232(+) (comYB) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MISFLRRDISIPGRQGLKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYVTSMEASLLKGNGLADMLAAL
GYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKRKTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLL
HLPHYFLGFCLLVLLLIGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEMMSNEKS
QLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELDIYSQESWETFFSQLNRATQWIQPIIFLV
VAVVIVMIYAAILLPIYQHMGDVF

Nucleotide

• Length: 1035 bp

>NTDB_id=506520 I2436_RS00705 WP_227687788.1 123198..124232(+) (comYB) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
TTGATCAGCTTCTTGCGGAGGGACATCTCAATACCGGGCAGGCAAGGCTTGAAAAAATTATCCAGTAAGCAGCAGGAAAA
GCTTATCCAATTGCTCTATAACCTATTGTCTAACGGCTTTAATTTGACAGAGGTCATTGCTTTTTTGAGAAAAAGCCAGC
TGCTACTGCCAGTCTATGTTACAAGTATGGAAGCAAGCCTATTAAAGGGCAACGGCCTTGCTGACATGCTAGCAGCCTTA
GGTTACTCTGATGCTGTTATGACACAAATTAATCTGGCAGATAAGCATGGCAATATCAAGCTAACCTTGGAAAAAATTCA
GGACTATCTGAGTCAATTTCGCCAAATCAAGCGAAAGACCATCGAGGCAGTCACTTATCCGATTATACTTTTGGGTTTTT
TAGTGGTTATCATGCTAGGCTTGCGGCATTACCTAATCCCTCAGCTAGAGAGTCAAAATACCTTGACTGACTTGTTGCTT
CATTTGCCTCATTATTTCTTAGGTTTTTGTTTGCTTGTGCTGTTGCTAATTGGCTCTTTTTACCTATATGCCAAGTCCTG
TAGTCGGCTAAAACTATTTAGTCAGCTGAGCTATTATCCTATCATTGGGTCCTTATTGCGGCAATATTTGACAGCCTACT
ATGCTAGGGAATGGGGGAACCTCATCGGACAAGGCTTAGAATTAATCACCATTTTGGAGATGATGTCAAACGAAAAGTCA
CAGCTCATGCGAGAGCTTGCCAAGGATATCAAGCAGAGTCTACTAGCTGGCCAATCCTTTCATCAAAGGGTTGCAGCTTA
TCCCTTTTTTAAAAAGGAGCTAAGCCTAATGATTGAATATGGTGACATCAAATCAAAGCTTGGTCAGGAATTAGATATCT
ATTCCCAAGAAAGCTGGGAGACCTTTTTTAGTCAGCTTAATCGGGCAACACAATGGATCCAGCCGATTATTTTTTTAGTG
GTTGCTGTGGTTATTGTGATGATTTATGCTGCTATTTTATTACCAATTTATCAACATATGGGAGATGTTTTTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (215-335)

• Type II secretion system (T2SS), protein F (T2SSF) (29-147)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	53.982	98.547	0.532
comYB	Streptococcus mutans UA159	53.982	98.547	0.532
comYB	Streptococcus gordonii str. Challis substr. CH1	52.059	98.837	0.515
comGB/cglB	Streptococcus mitis NCTC 12261	48.81	97.674	0.477
comGB/cglB	Streptococcus mitis SK321	49.249	96.802	0.477
comGB/cglB	Streptococcus pneumoniae Rx1	48.649	96.802	0.471
comGB/cglB	Streptococcus pneumoniae D39	48.649	96.802	0.471
comGB/cglB	Streptococcus pneumoniae R6	48.649	96.802	0.471
comGB/cglB	Streptococcus pneumoniae TIGR4	48.649	96.802	0.471
comGB	Lactococcus lactis subsp. cremoris KW2	46.933	94.767	0.445