Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   I2436_RS00725 Genome accession   NZ_CP065060
Coordinates   125193..125627 (+) Length   144 a.a.
NCBI ID   WP_037580631.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ28     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 120193..130627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2436_RS00695 (GDAKBCAL_00139) - 121502..122170 (+) 669 WP_043052639.1 ATP-binding cassette domain-containing protein -
  I2436_RS00700 (GDAKBCAL_00140) comGA/cglA 122327..123265 (+) 939 WP_164437804.1 competence type IV pilus ATPase ComGA Machinery gene
  I2436_RS00705 (GDAKBCAL_00141) comYB 123198..124232 (+) 1035 WP_227687788.1 competence type IV pilus assembly protein ComGB Machinery gene
  I2436_RS00710 (GDAKBCAL_00142) comGC/cglC 124233..124556 (+) 324 WP_206152868.1 competence type IV pilus major pilin ComGC Machinery gene
  I2436_RS00715 (GDAKBCAL_00143) comGD 124534..124959 (+) 426 WP_206152869.1 competence type IV pilus minor pilin ComGD -
  I2436_RS00720 (GDAKBCAL_00144) comGE 124916..125206 (+) 291 WP_014622143.1 competence type IV pilus minor pilin ComGE -
  I2436_RS00725 (GDAKBCAL_00145) comYF 125193..125627 (+) 435 WP_037580631.1 competence type IV pilus minor pilin ComGF Machinery gene
  I2436_RS00730 (GDAKBCAL_00146) comGG 125605..125967 (+) 363 WP_012514785.1 competence type IV pilus minor pilin ComGG -
  I2436_RS00735 (GDAKBCAL_00147) comYH 126029..126982 (+) 954 WP_012514788.1 class I SAM-dependent methyltransferase Machinery gene
  I2436_RS00740 (GDAKBCAL_00148) - 127042..128244 (+) 1203 WP_012514789.1 acetate kinase -
  I2436_RS00745 (GDAKBCAL_00149) - 128616..129230 (-) 615 WP_021320266.1 hypothetical protein -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16185.72 Da        Isoelectric Point: 10.1988

>NTDB_id=506522 I2436_RS00725 WP_037580631.1 125193..125627(+) (comYF) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMVSERYLAANDQDNWLLFSQQLRAELSGTTLQGVSNNRLYVEKDK
KTLSFGQVKSHDFRKAAGNGRGYQPMLFSLSSSQITAVGQQVIIKLKWQSGLERTFIYAFQEKG

Nucleotide


Download         Length: 435 bp        

>NTDB_id=506522 I2436_RS00725 WP_037580631.1 125193..125627(+) (comYF) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
TTGAAAGACAGTAGGCTAAAGGCTTTCACCTTGATAGAGTGCCTTATTGCCTTGCTTGTCATCTCAGGCTCTTTATTAGT
TTATCAGGCCTTAACCAAGAGCCTTATGGTGAGTGAGAGGTATCTAGCAGCAAATGATCAGGACAACTGGCTTTTGTTTT
CCCAGCAATTGCGAGCAGAGCTTTCAGGTACTACCTTACAGGGTGTCTCCAATAATAGGCTATATGTTGAGAAAGACAAG
AAAACTCTGTCCTTTGGACAGGTCAAAAGTCATGATTTTAGAAAAGCAGCTGGCAATGGTCGAGGCTATCAGCCCATGCT
GTTTAGCTTGTCAAGTAGCCAAATAACAGCAGTAGGTCAGCAGGTTATCATCAAGCTGAAATGGCAAAGCGGGTTAGAAA
GGACCTTTATTTATGCATTTCAAGAGAAGGGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(41-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

52.083

100

0.521
  comYF Streptococcus mutans UA159

51.389

100

0.514
  comGF/cglF Streptococcus mitis SK321

49.635

95.139

0.472
  comGF/cglF Streptococcus mitis NCTC 12261

48.905

95.139

0.465
  comGF Lactococcus lactis subsp. cremoris KW2

47.143

97.222

0.458
  comGF/cglF Streptococcus pneumoniae D39

47.445

95.139

0.451
  comGF/cglF Streptococcus pneumoniae R6

47.445

95.139

0.451
  comGF/cglF Streptococcus pneumoniae TIGR4

47.445

95.139

0.451
  comGF/cglF Streptococcus pneumoniae Rx1

47.445

95.139

0.451