Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   I2432_RS00750 Genome accession   NZ_CP065054
Coordinates   128306..129244 (+) Length   312 a.a.
NCBI ID   WP_206158897.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ13     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 123306..134244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2432_RS00730 (LJFMMFNO_00144) - 123464..124510 (+) 1047 WP_206158895.1 acyltransferase family protein -
  I2432_RS00735 (LJFMMFNO_00145) - 124571..124936 (+) 366 WP_012514777.1 DUF1033 family protein -
  I2432_RS00740 (LJFMMFNO_00146) - 125473..127476 (+) 2004 Protein_111 DUF1430 domain-containing protein -
  I2432_RS00745 (LJFMMFNO_00148) - 127478..128125 (+) 648 WP_206158896.1 ATP-binding cassette domain-containing protein -
  I2432_RS00750 (LJFMMFNO_00149) comGA/cglA 128306..129244 (+) 939 WP_206158897.1 competence type IV pilus ATPase ComGA Machinery gene
  I2432_RS00755 (LJFMMFNO_00150) comYB 129177..130211 (+) 1035 WP_249093266.1 competence type IV pilus assembly protein ComGB Machinery gene
  I2432_RS00760 (LJFMMFNO_00151) comGC/cglC 130212..130535 (+) 324 WP_206158899.1 competence type IV pilus major pilin ComGC Machinery gene
  I2432_RS00765 (LJFMMFNO_00152) comGD 130513..130938 (+) 426 WP_012514783.1 competence type IV pilus minor pilin ComGD -
  I2432_RS00770 (LJFMMFNO_00153) comGE 130895..131185 (+) 291 WP_206158900.1 competence type IV pilus minor pilin ComGE -
  I2432_RS00775 (LJFMMFNO_00154) comYF 131172..131606 (+) 435 WP_012677237.1 competence type IV pilus minor pilin ComGF Machinery gene
  I2432_RS00780 (LJFMMFNO_00155) comGG 131584..131946 (+) 363 WP_206152302.1 competence type IV pilus minor pilin ComGG -
  I2432_RS00785 (LJFMMFNO_00156) comYH 132008..132961 (+) 954 WP_037580627.1 class I SAM-dependent methyltransferase Machinery gene
  I2432_RS00790 (LJFMMFNO_00157) - 133021..134220 (+) 1200 WP_165627047.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35382.60 Da        Isoelectric Point: 7.1375

>NTDB_id=506279 I2432_RS00750 WP_206158897.1 128306..129244(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ13]
MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDDTKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFNGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQANRWNQQIDQLLAEGHLNSRQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=506279 I2432_RS00750 WP_206158897.1 128306..129244(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ13]
ATGATTCAAGAATTAGCCAAGCGGCTTATCAGGCAGGCTGAAGAATTGCAGGCTCAGGATATTTATATACTACCAAGGGG
GACAGGCTATGAGCTTTTGATGAGGGTAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGAGAAAAAAGACGCTGTCAGCTCGGTGCTTGTGACTACGAC
CTTGATGACACTAAGGTGTCTCTACGATTATCAGCTGTGGGTGATTATCAGGGACAGGAGAGCTTAGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTAATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCTAGAGGCCTTT
ACCTCTTTTCTGGACCAGTCGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATAAAAAATGACCAGCTCCTGCAATTACAGGTTAACGATAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTTTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATTAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAACCGGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATAGCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

67.419

99.359

0.67
  comYA Streptococcus mutans UA159

63.344

99.679

0.631
  comYA Streptococcus mutans UA140

63.344

99.679

0.631
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.935

99.359

0.615
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.613

99.359

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

61.29

99.359

0.609
  comGA Lactococcus lactis subsp. cremoris KW2

52.09

99.679

0.519
  comGA Latilactobacillus sakei subsp. sakei 23K

40.909

91.667

0.375