NTDB

Overview

Name	pilA	Type	Machinery gene
Locus tag	INP91_RS08715	Genome accession	NZ_CP063123
Coordinates	1808191..1808634 (+)	Length	147 a.a.
NCBI ID	WP_049379953.1	Uniprot ID	-
Organism	Haemophilus parainfluenzae strain M1C120_2
Function	type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1803191..1813634

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INP91_RS08685 (INP91_08680)	tadA	1803406..1803924 (-)	519	WP_178160907.1	tRNA adenosine(34) deaminase TadA	-
INP91_RS08690 (INP91_08685)	-	1803934..1804785 (-)	852	WP_070582536.1	thymidylate synthase	-
INP91_RS08695 (INP91_08690)	lgt	1804798..1805604 (-)	807	WP_070582537.1	prolipoprotein diacylglyceryl transferase	-
INP91_RS08700 (INP91_08695)	-	1805613..1806407 (-)	795	WP_197545827.1	sulfite exporter TauE/SafE family protein	-
INP91_RS08705 (INP91_08700)	rppH	1806407..1807000 (-)	594	WP_070582539.1	RNA pyrophosphohydrolase	-
INP91_RS08710 (INP91_08705)	ampD	1807485..1808048 (-)	564	WP_070582540.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
INP91_RS08715 (INP91_08710)	pilA	1808191..1808634 (+)	444	WP_049379953.1	prepilin peptidase-dependent pilin	Machinery gene
INP91_RS08720 (INP91_08715)	pilB	1808641..1810020 (+)	1380	WP_197545828.1	GspE/PulE family protein	Machinery gene
INP91_RS08725 (INP91_08720)	pilC	1810029..1811252 (+)	1224	WP_197545829.1	type II secretion system F family protein	Machinery gene
INP91_RS08730 (INP91_08725)	pilD	1811249..1811926 (+)	678	WP_197545830.1	prepilin peptidase	Machinery gene
INP91_RS08735 (INP91_08730)	coaE	1812015..1812635 (+)	621	WP_197545831.1	dephospho-CoA kinase	-
INP91_RS08740 (INP91_08735)	yacG	1812628..1812834 (+)	207	WP_005695505.1	DNA gyrase inhibitor YacG	-
INP91_RS08745 (INP91_08740)	-	1812831..1813112 (+)	282	WP_014064065.1	GNAT family N-acetyltransferase	-

Sequence

Protein

Download Length: 147 a.a. Molecular weight: 15111.35 Da Isoelectric Point: 8.4674

                                >NTDB_id=493180 INP91_RS08715 WP_049379953.1 1808191..1808634(+) (pilA) [Haemophilus parainfluenzae strain M1C120_2]

MKLTFSKPLHKGFTLIELMIVIAIIAILATIAIPSYQNYTKKAAISELLQASAPYKSDVELCVYSTNAPTNCSGGSNGIA

ADITTAKGYVKSITTKSGVITVTGNGALDGISYSLTATGSTSSGVTWTTACPSNADLFPAGFCSSAK

Nucleotide

Download Length: 444 bp

                                >NTDB_id=493180 INP91_RS08715 WP_049379953.1 1808191..1808634(+) (pilA) [Haemophilus parainfluenzae strain M1C120_2]

ATGAAACTGACTTTTTCTAAACCTTTACATAAAGGTTTTACGTTAATTGAATTGATGATCGTGATTGCGATTATTGCTAT

TCTCGCGACGATCGCCATTCCGTCTTATCAAAATTATACCAAAAAAGCGGCTATCTCCGAATTGTTGCAAGCATCTGCAC

CTTATAAATCTGATGTGGAGTTATGTGTCTATAGCACCAATGCCCCGACAAACTGTTCAGGTGGTTCAAATGGCATTGCA

GCAGACATCACTACTGCAAAAGGCTATGTCAAATCCATTACCACAAAATCAGGTGTGATTACGGTGACAGGAAATGGTGC

ATTGGATGGGATCAGTTATTCTTTAACGGCGACAGGCTCAACCTCATCAGGTGTTACCTGGACAACTGCTTGCCCAAGTA

ATGCTGATTTATTCCCTGCAGGCTTCTGTTCTTCTGCTAAATAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(10-32)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
pilA	Haemophilus influenzae 86-028NP	75.342	99.32	0.748
pilA	Haemophilus influenzae Rd KW20	73.288	99.32	0.728
pilA	Glaesserella parasuis strain SC1401	56.081	100	0.565
pilA	Vibrio campbellii strain DS40M4	41.096	99.32	0.408
pilE	Neisseria gonorrhoeae MS11	41.985	89.116	0.374
pilA2	Legionella pneumophila str. Paris	42.188	87.075	0.367
pilA	Vibrio cholerae O1 biovar El Tor strain E7946	34.868	100	0.361
pilA	Vibrio cholerae strain A1552	34.868	100	0.361
pilA	Vibrio cholerae C6706	34.868	100	0.361

Detailed information NTG0493180