NTDB

Overview

Name	pilA	Type	Machinery gene
Locus tag	INP96_RS00260	Genome accession	NZ_CP063116
Coordinates	51730..52173 (+)	Length	147 a.a.
NCBI ID	WP_049369499.1	Uniprot ID	-
Organism	Haemophilus parainfluenzae strain M1C146_1
Function	type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 46730..57173

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INP96_RS00230 (INP96_00230)	tadA	46944..47462 (-)	519	WP_197555885.1	tRNA adenosine(34) deaminase TadA	-
INP96_RS00235 (INP96_00235)	-	47472..48323 (-)	852	WP_197555886.1	thymidylate synthase	-
INP96_RS00240 (INP96_00240)	lgt	48334..49143 (-)	810	WP_197555887.1	prolipoprotein diacylglyceryl transferase	-
INP96_RS00245 (INP96_00245)	-	49152..49946 (-)	795	WP_197555888.1	sulfite exporter TauE/SafE family protein	-
INP96_RS00250 (INP96_00250)	rppH	49946..50539 (-)	594	WP_197555889.1	RNA pyrophosphohydrolase	-
INP96_RS00255 (INP96_00255)	ampD	51024..51587 (-)	564	WP_197555890.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
INP96_RS00260 (INP96_00260)	pilA	51730..52173 (+)	444	WP_049369499.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
INP96_RS00265 (INP96_00265)	pilB	52180..53559 (+)	1380	WP_111327324.1	GspE/PulE family protein	Machinery gene
INP96_RS00270 (INP96_00270)	pilC	53568..54791 (+)	1224	WP_197555891.1	type II secretion system F family protein	Machinery gene
INP96_RS00275 (INP96_00275)	pilD	54788..55465 (+)	678	WP_197555892.1	prepilin peptidase	Machinery gene
INP96_RS00280 (INP96_00280)	coaE	55552..56172 (+)	621	WP_197555893.1	dephospho-CoA kinase	-
INP96_RS00285 (INP96_00285)	yacG	56165..56371 (+)	207	WP_111327320.1	DNA gyrase inhibitor YacG	-
INP96_RS00290 (INP96_00290)	-	56368..56649 (+)	282	WP_111327319.1	GNAT family N-acetyltransferase	-

Sequence

Protein

Download Length: 147 a.a. Molecular weight: 15125.38 Da Isoelectric Point: 8.4674

                                >NTDB_id=492998 INP96_RS00260 WP_049369499.1 51730..52173(+) (pilA) [Haemophilus parainfluenzae strain M1C146_1]

MKLTFSKPLHKGFTLIELMIVIAIIAILATIAIPSYQNYTKKAAISELLQASAPYKSDVELCIYSTNAPTNCSGGSNGIA

ADITTAKGYVKSITTKSGVITVTGNGALDGISYSLTATGSTSSGVTWTTACPSNADLFPAGFCSSAK

Nucleotide

Download Length: 444 bp

                                >NTDB_id=492998 INP96_RS00260 WP_049369499.1 51730..52173(+) (pilA) [Haemophilus parainfluenzae strain M1C146_1]

ATGAAACTGACTTTTTCTAAACCTTTACATAAAGGTTTTACGTTAATTGAATTGATGATCGTAATTGCGATTATTGCTAT

TCTCGCGACGATCGCCATTCCGTCTTATCAAAATTATACCAAAAAAGCGGCTATCTCCGAATTGTTACAAGCTTCTGCAC

CTTATAAATCTGATGTGGAACTATGTATCTATAGCACCAATGCCCCAACAAACTGTTCAGGTGGCTCAAATGGCATTGCT

GCAGACATCACAACCGCAAAAGGCTATGTCAAATCCATCACCACGAAATCGGGGGTGATTACGGTGACAGGAAATGGTGC

ATTAGATGGGATCAGTTATTCTTTAACGGCGACAGGTTCAACCTCATCAGGTGTCACCTGGACAACCGCTTGCCCAAGCA

ATGCAGATTTATTCCCTGCAGGTTTCTGCTCTTCAGCTAAATAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(10-32)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
pilA	Haemophilus influenzae 86-028NP	74.658	99.32	0.742
pilA	Haemophilus influenzae Rd KW20	72.603	99.32	0.721
pilA	Glaesserella parasuis strain SC1401	56.757	100	0.571
pilA	Vibrio campbellii strain DS40M4	41.096	99.32	0.408
pilE	Neisseria gonorrhoeae MS11	41.985	89.116	0.374
pilA2	Legionella pneumophila strain ERS1305867	42.188	87.075	0.367
pilA2	Legionella pneumophila str. Paris	42.188	87.075	0.367
pilA	Vibrio cholerae C6706	35.526	100	0.367
pilA	Vibrio cholerae O1 biovar El Tor strain E7946	35.526	100	0.367
pilA	Vibrio cholerae strain A1552	35.526	100	0.367

Detailed information NTG0492998