Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   INP96_RS00270 Genome accession   NZ_CP063116
Coordinates   53568..54791 (+) Length   407 a.a.
NCBI ID   WP_197555891.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C146_1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 48568..59791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP96_RS00245 (INP96_00245) - 49152..49946 (-) 795 WP_197555888.1 sulfite exporter TauE/SafE family protein -
  INP96_RS00250 (INP96_00250) rppH 49946..50539 (-) 594 WP_197555889.1 RNA pyrophosphohydrolase -
  INP96_RS00255 (INP96_00255) ampD 51024..51587 (-) 564 WP_197555890.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  INP96_RS00260 (INP96_00260) pilA 51730..52173 (+) 444 WP_049369499.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  INP96_RS00265 (INP96_00265) pilB 52180..53559 (+) 1380 WP_111327324.1 GspE/PulE family protein Machinery gene
  INP96_RS00270 (INP96_00270) pilC 53568..54791 (+) 1224 WP_197555891.1 type II secretion system F family protein Machinery gene
  INP96_RS00275 (INP96_00275) pilD 54788..55465 (+) 678 WP_197555892.1 prepilin peptidase Machinery gene
  INP96_RS00280 (INP96_00280) coaE 55552..56172 (+) 621 WP_197555893.1 dephospho-CoA kinase -
  INP96_RS00285 (INP96_00285) yacG 56165..56371 (+) 207 WP_111327320.1 DNA gyrase inhibitor YacG -
  INP96_RS00290 (INP96_00290) - 56368..56649 (+) 282 WP_111327319.1 GNAT family N-acetyltransferase -
  INP96_RS00295 (INP96_00295) rhlB 56740..57999 (+) 1260 WP_197555894.1 ATP-dependent RNA helicase RhlB -
  INP96_RS00300 (INP96_00300) mreD 58041..58529 (-) 489 WP_111327318.1 rod shape-determining protein MreD -
  INP96_RS00305 (INP96_00305) mreC 58529..59593 (-) 1065 WP_070582548.1 rod shape-determining protein MreC -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46108.60 Da        Isoelectric Point: 9.6103

>NTDB_id=493000 INP96_RS00270 WP_197555891.1 53568..54791(+) (pilC) [Haemophilus parainfluenzae strain M1C146_1]
MAKQKLFYFQAYDQRQQWQKGSLVAQSKQAAQFLLIAKGFSHIRLQQDWQLNQKPKNAEISALLNQLATLLSSAIPLKNA
LHILQDNCTQLGLHQWLSALIELIESGLPFSQSLEIQGKYLNFQEIQLIQVGEMTGKLAEVCTKIAERRTQSLTLQRKLQ
KIMLYPAMVLGISLSLTLILLLFVVPQFAEMYGENSADLPTLTAVLLAMSQFLQHHFVALMIACTFAIFMLKMALKHSLW
LNQKKNALISHMPIWGNIICLSRLISFSHNLQLMLQSGVALTPALNSFLPKQQTWQTQRALKGDILLQQEVRSILQWVSQ
GYPFSESVSSHLFPMEAQQMLQIGEKSGKLALMLRHIADNYQEKLNHQIDLLSQLLEPLMMLIIGSLIGIIMIGMYLPIF
NMGSVIQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=493000 INP96_RS00270 WP_197555891.1 53568..54791(+) (pilC) [Haemophilus parainfluenzae strain M1C146_1]
ATGGCAAAGCAAAAACTCTTTTATTTCCAAGCCTATGATCAGCGACAACAATGGCAAAAAGGTAGCCTTGTTGCTCAATC
TAAACAAGCCGCACAATTTCTGTTAATTGCAAAAGGTTTTAGTCACATTCGCTTGCAACAAGATTGGCAACTTAATCAGA
AACCGAAAAATGCAGAAATCAGTGCTTTATTGAATCAACTGGCTACATTGCTCAGTTCTGCCATTCCATTAAAAAATGCA
CTACATATTTTGCAAGACAACTGCACACAATTGGGTTTGCATCAGTGGCTTAGCGCCTTAATTGAGTTAATTGAAAGTGG
TCTTCCGTTTTCACAAAGCTTGGAAATACAAGGAAAGTATTTAAACTTTCAAGAGATTCAACTTATTCAAGTGGGAGAAA
TGACAGGAAAACTGGCAGAGGTATGCACTAAAATTGCAGAACGTCGAACGCAATCATTAACGCTTCAACGCAAATTACAA
AAAATTATGCTTTATCCAGCCATGGTATTAGGTATTTCGCTTTCACTTACGTTGATTTTATTACTCTTCGTTGTACCACA
ATTTGCTGAAATGTATGGCGAAAATTCCGCTGATTTGCCTACATTAACCGCCGTATTATTAGCTATGTCTCAATTCCTAC
AACATCATTTTGTTGCGTTAATGATTGCCTGCACTTTCGCTATTTTTATGTTGAAGATGGCATTAAAACATTCCCTTTGG
CTAAATCAAAAAAAGAATGCACTAATTAGTCACATGCCAATTTGGGGCAATATCATTTGCCTTTCTCGCCTAATCAGTTT
TAGCCATAACCTGCAATTAATGCTTCAATCAGGAGTGGCATTAACGCCAGCCTTAAATAGTTTCCTACCCAAACAACAAA
CCTGGCAAACACAACGTGCCTTAAAAGGCGATATCCTACTACAACAAGAAGTGCGGTCAATTTTACAGTGGGTTTCTCAA
GGTTATCCATTTTCAGAAAGTGTCAGTAGTCATCTTTTCCCAATGGAAGCACAACAAATGCTACAGATTGGAGAGAAAAG
TGGAAAACTTGCATTGATGTTGCGTCATATTGCTGATAACTATCAAGAAAAACTTAATCATCAAATTGATTTACTTTCCC
AACTTTTAGAGCCTTTAATGATGCTCATCATTGGTAGTTTAATTGGTATCATAATGATAGGCATGTATCTGCCGATTTTT
AATATGGGATCCGTAATCCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

69.059

99.263

0.685
  pilC Haemophilus influenzae 86-028NP

68.317

99.263

0.678
  pilC Glaesserella parasuis strain SC1401

40.15

98.526

0.396