Detailed information NTG0479615

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: IBB97_RS09250
• Genome accession: NZ_CP061021
• Coordinates: 1782190..1782516 (-)
• Length: 108 a.a.
• NCBI ID: WP_002946126.1
• Uniprot ID: A0A0E2Q1B3
• Organism: Streptococcus thermophilus strain 24739
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1777190..1787516

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBB97_RS09215 (IBB97_09230)	-	1777510..1778703 (-)	1194	WP_014608740.1	acetate kinase	-
IBB97_RS09220 (IBB97_09235)	comYH	1778759..1779715 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
IBB97_RS09225 (IBB97_09240)	comGG	1779760..1780080 (-)	321	WP_278249177.1	competence type IV pilus minor pilin ComGG	-
IBB97_RS09230 (IBB97_09245)	-	1780101..1781036 (-)	936	WP_138496752.1	IS30 family transposase	-
IBB97_RS09235 (IBB97_09250)	comYF	1781119..1781553 (-)	435	WP_138496599.1	competence type IV pilus minor pilin ComGF	Machinery gene
IBB97_RS09240 (IBB97_09255)	comGE	1781537..1781830 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
IBB97_RS09245 (IBB97_09260)	comYD	1781802..1782230 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
IBB97_RS09250 (IBB97_09265)	comYC	1782190..1782516 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
IBB97_RS09255 (IBB97_09270)	comYB	1782513..1783613 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
IBB97_RS09260 (IBB97_09275)	comGA/cglA/cilD	1783495..1784436 (-)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
IBB97_RS09265 (IBB97_09280)	-	1784517..1784879 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 11914.00 Da
• Isoelectric Point: 9.9219

>NTDB_id=479615 IBB97_RS09250 WP_002946126.1 1782190..1782516(-) (comYC) [Streptococcus thermophilus strain 24739]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide

• Length: 327 bp

>NTDB_id=479615 IBB97_RS09250 WP_002946126.1 1782190..1782516(-) (comYC) [Streptococcus thermophilus strain 24739]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTAGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: A0A0E2Q1B3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus mutans UA140	69.231	96.296	0.667
comYC	Streptococcus mutans UA159	69.231	96.296	0.667
comYC	Streptococcus gordonii str. Challis substr. CH1	63.81	97.222	0.62
comGC/cglC	Streptococcus mitis SK321	62.264	98.148	0.611
comGC/cglC	Streptococcus mitis NCTC 12261	58.333	100	0.583
comGC/cglC	Streptococcus pneumoniae D39	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae R6	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae Rx1	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae TIGR4	58.491	98.148	0.574
comGC	Lactococcus lactis subsp. cremoris KW2	56.604	98.148	0.556
comYC	Streptococcus suis isolate S10	60.227	81.481	0.491
comGC	Staphylococcus aureus MW2	50	72.222	0.361
comGC	Staphylococcus aureus N315	50	72.222	0.361