Detailed information NTG0466782

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: H0A38_RS11125
• Genome accession: NZ_CP059048
• Coordinates: 2256107..2256490 (-)
• Length: 127 a.a.
• NCBI ID: WP_012898622.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain LAC460
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2251107..2261490

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0A38_RS11085 (H0A38_11025)	-	2251643..2252452 (-)	810	WP_014570791.1	metal ABC transporter permease	-
H0A38_RS11090 (H0A38_11030)	-	2252445..2253182 (-)	738	WP_012898617.1	metal ABC transporter ATP-binding protein	-
H0A38_RS11095 (H0A38_11035)	-	2253359..2254201 (-)	843	WP_015427160.1	metal ABC transporter substrate-binding protein	-
H0A38_RS11100 (H0A38_11040)	-	2254198..2254635 (-)	438	WP_010906313.1	zinc-dependent MarR family transcriptional regulator	-
H0A38_RS11105 (H0A38_11045)	comGG	2254716..2255000 (-)	285	WP_017865155.1	competence type IV pilus minor pilin ComGG	Machinery gene
H0A38_RS11110 (H0A38_11050)	comGF	2255039..2255485 (-)	447	WP_165379808.1	competence type IV pilus minor pilin ComGF	Machinery gene
H0A38_RS11115 (H0A38_11055)	comGE	2255448..2255744 (-)	297	WP_033900709.1	competence type IV pilus minor pilin ComGE	Machinery gene
H0A38_RS11120 (H0A38_11060)	comGD	2255716..2256147 (-)	432	WP_226319344.1	competence type IV pilus minor pilin ComGD	Machinery gene
H0A38_RS11125 (H0A38_11065)	comGC	2256107..2256490 (-)	384	WP_012898622.1	competence type IV pilus major pilin ComGC	Machinery gene
H0A38_RS11130 (H0A38_11070)	comGB	2256504..2257577 (-)	1074	WP_080735950.1	competence type IV pilus assembly protein ComGB	Machinery gene
H0A38_RS11135 (H0A38_11075)	comGA	2257471..2258409 (-)	939	WP_033900707.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 127 a.a.
• Molecular weight: 14825.41 Da
• Isoelectric Point: 8.4563

>NTDB_id=466782 H0A38_RS11125 WP_012898622.1 2256107..2256490(-) (comGC) [Lactococcus lactis strain LAC460]
MERTKKFILKKIQKIFLFVKICEKKCRQKELRAFTLIEMLIVLAIISILILLFVPNLIKEKSQVQKTGEAAVVKVVESQA
QLYELDHDDEKPSLSELLSAGMITQKQISAYDNYYDQNKNEERNFND

Nucleotide

• Length: 384 bp

>NTDB_id=466782 H0A38_RS11125 WP_012898622.1 2256107..2256490(-) (comGC) [Lactococcus lactis strain LAC460]
ATGGAAAGAACTAAGAAGTTTATTTTAAAGAAAATACAAAAAATATTTTTATTCGTTAAAATTTGTGAAAAAAAATGCCG
TCAGAAAGAGCTAAGAGCTTTTACTTTGATAGAGATGTTAATTGTACTAGCTATTATTAGTATTTTGATATTACTATTTG
TTCCAAATTTAATTAAAGAAAAATCACAAGTTCAAAAAACTGGAGAAGCGGCAGTTGTAAAAGTAGTAGAAAGTCAAGCT
CAACTTTATGAATTAGATCATGATGATGAGAAGCCGAGTCTGTCAGAATTGCTCAGCGCTGGGATGATTACTCAAAAACA
AATTTCTGCTTACGATAATTACTATGATCAGAATAAAAATGAAGAACGAAATTTTAATGACTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (32-52)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Lactococcus lactis subsp. cremoris KW2	80.172	91.339	0.732
comYC	Streptococcus mutans UA159	56.436	79.528	0.449
comYC	Streptococcus mutans UA140	56.436	79.528	0.449
comGC/cglC	Streptococcus mitis SK321	55.446	79.528	0.441
comYC	Streptococcus gordonii str. Challis substr. CH1	55.556	77.953	0.433
comGC/cglC	Streptococcus pneumoniae TIGR4	53.465	79.528	0.425
comGC/cglC	Streptococcus pneumoniae Rx1	53.465	79.528	0.425
comGC/cglC	Streptococcus pneumoniae D39	53.465	79.528	0.425
comGC/cglC	Streptococcus pneumoniae R6	53.465	79.528	0.425
comGC/cglC	Streptococcus mitis NCTC 12261	57.303	70.079	0.402
comYC	Streptococcus suis isolate S10	55.682	69.291	0.386