Detailed information NTG0466783

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: H0A38_RS11130
• Genome accession: NZ_CP059048
• Coordinates: 2256504..2257577 (-)
• Length: 357 a.a.
• NCBI ID: WP_080735950.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain LAC460
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2251504..2262577

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0A38_RS11085 (H0A38_11025)	-	2251643..2252452 (-)	810	WP_014570791.1	metal ABC transporter permease	-
H0A38_RS11090 (H0A38_11030)	-	2252445..2253182 (-)	738	WP_012898617.1	metal ABC transporter ATP-binding protein	-
H0A38_RS11095 (H0A38_11035)	-	2253359..2254201 (-)	843	WP_015427160.1	metal ABC transporter substrate-binding protein	-
H0A38_RS11100 (H0A38_11040)	-	2254198..2254635 (-)	438	WP_010906313.1	zinc-dependent MarR family transcriptional regulator	-
H0A38_RS11105 (H0A38_11045)	comGG	2254716..2255000 (-)	285	WP_017865155.1	competence type IV pilus minor pilin ComGG	Machinery gene
H0A38_RS11110 (H0A38_11050)	comGF	2255039..2255485 (-)	447	WP_165379808.1	competence type IV pilus minor pilin ComGF	Machinery gene
H0A38_RS11115 (H0A38_11055)	comGE	2255448..2255744 (-)	297	WP_033900709.1	competence type IV pilus minor pilin ComGE	Machinery gene
H0A38_RS11120 (H0A38_11060)	comGD	2255716..2256147 (-)	432	WP_226319344.1	competence type IV pilus minor pilin ComGD	Machinery gene
H0A38_RS11125 (H0A38_11065)	comGC	2256107..2256490 (-)	384	WP_012898622.1	competence type IV pilus major pilin ComGC	Machinery gene
H0A38_RS11130 (H0A38_11070)	comGB	2256504..2257577 (-)	1074	WP_080735950.1	competence type IV pilus assembly protein ComGB	Machinery gene
H0A38_RS11135 (H0A38_11075)	comGA	2257471..2258409 (-)	939	WP_033900707.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 40296.49 Da
• Isoelectric Point: 10.3000

>NTDB_id=466783 H0A38_RS11130 WP_080735950.1 2256504..2257577(-) (comGB) [Lactococcus lactis strain LAC460]
MSLGHQKIGIKKLISYLQMDISHLLKPKGKKLRLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLA
SGQALSELLESLSFSKNVVTQLALVEVHGNLSGTMQLVELHLKKQLKVKNKLVEVATYPILLLIFLVGIMWGLKNYLLPQ
LNSGSNFATLLINHLPLVFFSFGAFIFLLTALSVTLLKRKSAIMNFTFLVKLPLVHSFIRLYLTAYFAREWGNLIAQGVE
LRQIINLMKKQKSRIFSEVGKNLDLELNAGRSFEQAVSKLALFLPELSLMIEYGAIKDKLGLELSLYADECWEQFFTKID
RLMQLIQPLVFIFVALMIILLYAAMLLPIYSNMGSGI

Nucleotide

• Length: 1074 bp

>NTDB_id=466783 H0A38_RS11130 WP_080735950.1 2256504..2257577(-) (comGB) [Lactococcus lactis strain LAC460]
TTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTACTTACAAATGGATATCTCACACCTACTGAAGCC
AAAAGGGAAAAAATTAAGACTGATTAAACAAGCCAAACTTATCCAACTGATGGGAAATCTTTTGAATAGTGGATTTAATT
TAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTACATTAAAAATGAAAGAAGGTCTCGCT
TCTGGTCAAGCTTTATCAGAGCTTTTAGAAAGTCTTTCATTTTCTAAAAATGTGGTGACACAACTTGCTTTGGTAGAAGT
GCATGGTAACTTGTCAGGGACGATGCAATTAGTTGAACTTCATCTAAAAAAACAGCTTAAAGTTAAAAATAAATTAGTGG
AAGTTGCTACTTATCCAATATTGTTATTAATTTTTCTGGTTGGAATTATGTGGGGCTTAAAAAATTATTTACTACCACAA
CTCAATAGTGGCAGTAACTTTGCTACTCTATTGATTAATCATTTACCCTTAGTATTTTTTTCGTTTGGAGCTTTTATATT
TTTACTGACAGCTTTGTCAGTAACTCTTTTAAAACGAAAATCAGCAATAATGAATTTTACATTTCTTGTTAAATTACCTC
TGGTTCATTCTTTTATCCGTTTATATTTAACAGCTTACTTTGCAAGAGAATGGGGAAATCTAATTGCTCAAGGTGTTGAA
TTACGTCAAATTATTAACTTGATGAAAAAACAAAAAAGTCGAATTTTTTCAGAAGTTGGCAAGAATCTTGATTTAGAATT
GAATGCTGGTCGGTCTTTTGAACAAGCTGTCAGTAAACTTGCGCTTTTTTTACCCGAGCTCTCGTTAATGATTGAATATG
GAGCTATTAAAGATAAATTAGGCTTAGAGCTTTCGCTTTATGCGGATGAATGTTGGGAACAATTTTTTACAAAGATAGAT
CGTTTAATGCAATTAATCCAACCTCTTGTTTTTATTTTCGTAGCATTGATGATTATTTTGCTATATGCAGCCATGTTACT
CCCCATCTATTCAAATATGGGTTCGGGAATATAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (227-348)

• Type II secretion system (T2SS), protein F (T2SSF) (41-159)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Lactococcus lactis subsp. cremoris KW2	83.284	95.518	0.796
comYB	Streptococcus gordonii str. Challis substr. CH1	53.666	95.518	0.513
comYB	Streptococcus mutans UA140	52.647	95.238	0.501
comYB	Streptococcus mutans UA159	52.353	95.238	0.499
comGB/cglB	Streptococcus mitis SK321	51.343	93.838	0.482
comGB/cglB	Streptococcus pneumoniae TIGR4	51.045	93.838	0.479
comGB/cglB	Streptococcus pneumoniae Rx1	51.045	93.838	0.479
comGB/cglB	Streptococcus pneumoniae D39	51.045	93.838	0.479
comGB/cglB	Streptococcus pneumoniae R6	51.045	93.838	0.479
comGB/cglB	Streptococcus mitis NCTC 12261	50.448	93.838	0.473