Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FOC63_RS04590 Genome accession   NZ_CP054015
Coordinates   906846..907787 (+) Length   313 a.a.
NCBI ID   WP_009853229.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain FDAARGOS_755     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 901846..912787
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC63_RS04580 (FOC63_04580) rpoC 902598..906236 (+) 3639 WP_012961326.1 DNA-directed RNA polymerase subunit beta' -
  FOC63_RS04585 (FOC63_04585) - 906407..906775 (+) 369 WP_009853228.1 DUF1033 family protein -
  FOC63_RS04590 (FOC63_04590) comYA 906846..907787 (+) 942 WP_009853229.1 competence type IV pilus ATPase ComGA Machinery gene
  FOC63_RS04595 (FOC63_04595) comYB 907669..908754 (+) 1086 WP_012961328.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOC63_RS04600 (FOC63_04600) comYC 908754..909047 (+) 294 WP_009853231.1 competence type IV pilus major pilin ComGC Machinery gene
  FOC63_RS04605 (FOC63_04605) comYD 909031..909462 (+) 432 WP_009853232.1 competence type IV pilus minor pilin ComGD Machinery gene
  FOC63_RS04610 (FOC63_04610) comGE 909416..909709 (+) 294 WP_012961329.1 competence type IV pilus minor pilin ComGE -
  FOC63_RS04615 (FOC63_04615) comYF 909663..910130 (+) 468 WP_012961330.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOC63_RS04620 (FOC63_04620) comYG 910102..910416 (+) 315 WP_009853235.1 competence type IV pilus minor pilin ComGG Machinery gene
  FOC63_RS04625 (FOC63_04625) comYH 910489..911445 (+) 957 WP_009853236.1 class I SAM-dependent methyltransferase Machinery gene
  FOC63_RS04630 (FOC63_04630) - 911498..912697 (+) 1200 WP_009853237.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35757.90 Da        Isoelectric Point: 5.3009

>NTDB_id=450141 FOC63_RS04590 WP_009853229.1 906846..907787(+) (comYA) [Streptococcus gallolyticus strain FDAARGOS_755]
MIQEKAKQLIKDAVEVNAQDIYILPREDCYEVYQRVGDQRQFVDYFELEQMTSLISHFKFVAGMNVGEKRRSQLGSCDYQ
FADEEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMKNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPNK
QVITIEDPVEIKQEQMLQLQLNSDIGMTYDELIKLSLRHRPDILIIGEIRDSETARAVIRASLTGAVVFSTIHAKSIPGI
YARLLELGVSQQELENSLRAIVYQRLIGGGGVIDFAKENFESHRPECWNTKIESLVKDGHITAEQAKIEKIAI

Nucleotide


Download         Length: 942 bp        

>NTDB_id=450141 FOC63_RS04590 WP_009853229.1 906846..907787(+) (comYA) [Streptococcus gallolyticus strain FDAARGOS_755]
ATGATTCAGGAAAAAGCAAAGCAACTCATTAAGGATGCTGTTGAAGTTAATGCGCAAGATATTTACATTTTACCTAGAGA
AGACTGTTATGAAGTGTATCAACGCGTGGGAGACCAACGGCAATTTGTTGATTATTTTGAGCTAGAGCAGATGACTAGCT
TGATTAGTCATTTTAAATTTGTGGCTGGTATGAATGTTGGGGAGAAACGTCGCAGCCAGCTAGGTTCTTGTGATTATCAA
TTTGCAGATGAGGAAGAGATTTCGCTTCGTTTGTCGAGTGTTGGTGATTATCGTGGACGAGAAAGTTTAGTGATTCGCTT
GCTTTATTCTGGTCGTCATGATTTGCAATATTGGTTTGACGGGATGAAAAATATTTTAGAAGCCATTGATAGTAGGGGGC
TTTACCTTTTTTCGGGACCAGTAGGGAGTGGAAAAACCACTCTCATGTACCAATTGGTTCGTGAAAAATTTCCTAATAAG
CAAGTCATTACAATTGAGGACCCTGTTGAAATCAAACAGGAACAAATGTTGCAGTTGCAGTTAAATAGTGATATTGGGAT
GACTTATGACGAGCTGATTAAATTATCGCTTCGCCATAGACCAGATATTCTGATTATCGGAGAAATTCGTGATAGCGAGA
CAGCGCGTGCAGTCATTCGTGCGAGTTTGACGGGAGCTGTTGTATTTTCGACCATTCATGCGAAGAGCATCCCTGGCATT
TATGCACGTCTTTTGGAATTAGGGGTTAGTCAGCAAGAATTGGAAAATAGTTTGCGTGCCATTGTTTATCAACGCTTAAT
TGGCGGAGGAGGTGTGATTGATTTTGCTAAAGAAAACTTTGAAAGTCACCGACCAGAGTGCTGGAATACAAAAATTGAAA
GTCTTGTTAAAGACGGACATATCACAGCTGAACAAGCAAAAATCGAAAAAATTGCCATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

68.81

99.361

0.684
  comYA Streptococcus mutans UA140

68.489

99.361

0.681
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

67.419

99.042

0.668
  comYA Streptococcus gordonii str. Challis substr. CH1

65.273

99.361

0.649
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

62.179

99.681

0.62
  comGA/cglA/cilD Streptococcus pneumoniae D39

62.179

99.681

0.62
  comGA/cglA/cilD Streptococcus pneumoniae R6

62.179

99.681

0.62
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

62.179

99.681

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.633

100

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.754

88.179

0.377