Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FOC63_RS04595 Genome accession   NZ_CP054015
Coordinates   907669..908754 (+) Length   361 a.a.
NCBI ID   WP_012961328.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain FDAARGOS_755     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 902669..913754
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC63_RS04585 (FOC63_04585) - 906407..906775 (+) 369 WP_009853228.1 DUF1033 family protein -
  FOC63_RS04590 (FOC63_04590) comYA 906846..907787 (+) 942 WP_009853229.1 competence type IV pilus ATPase ComGA Machinery gene
  FOC63_RS04595 (FOC63_04595) comYB 907669..908754 (+) 1086 WP_012961328.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOC63_RS04600 (FOC63_04600) comYC 908754..909047 (+) 294 WP_009853231.1 competence type IV pilus major pilin ComGC Machinery gene
  FOC63_RS04605 (FOC63_04605) comYD 909031..909462 (+) 432 WP_009853232.1 competence type IV pilus minor pilin ComGD Machinery gene
  FOC63_RS04610 (FOC63_04610) comGE 909416..909709 (+) 294 WP_012961329.1 competence type IV pilus minor pilin ComGE -
  FOC63_RS04615 (FOC63_04615) comYF 909663..910130 (+) 468 WP_012961330.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOC63_RS04620 (FOC63_04620) comYG 910102..910416 (+) 315 WP_009853235.1 competence type IV pilus minor pilin ComGG Machinery gene
  FOC63_RS04625 (FOC63_04625) comYH 910489..911445 (+) 957 WP_009853236.1 class I SAM-dependent methyltransferase Machinery gene
  FOC63_RS04630 (FOC63_04630) - 911498..912697 (+) 1200 WP_009853237.1 acetate kinase -
  FOC63_RS04635 (FOC63_04635) - 912859..913059 (+) 201 WP_012961332.1 helix-turn-helix transcriptional regulator -
  FOC63_RS04640 (FOC63_04640) - 913069..913278 (+) 210 WP_009853239.1 hypothetical protein -
  FOC63_RS04645 (FOC63_04645) - 913291..913743 (+) 453 WP_009853240.1 hypothetical protein -

Sequence

Protein


Download         Length: 361 a.a.        Molecular weight: 41149.94 Da        Isoelectric Point: 9.9289

>NTDB_id=450142 FOC63_RS04595 WP_012961328.1 907669..908754(+) (comYB) [Streptococcus gallolyticus strain FDAARGOS_755]
MLKKTLKVTDQSAGIQKLKVLLKTDISQLNKQKSKKLPFKKQRKVIQLFNNLFESGFNLTEIVSFLRRSQLLLDIYVERM
QESLLNGASLATMMADLGFSDNIVTQIALADVHGNSQKSLLKIESYLSSMTVVRKKLIEVATYPLILLLFLILIMLGLKN
YLLPQLESQNVATQIITHFPTIFLLSIFSIGVLLVCATFYARRLSQIDLYSRISRIPLVGNYVRLYLTAYYAREWGNLIG
QGIELMAIVGIMQKQKSLLFQEIGKDMEEALLSGQAFHQKVLGYPFFLRELSLMIEYGEVKSKLGRELDIYAEETWQSFF
GKLTQATQLIQPLVFVFVALIIVLIYVAMLLPMYQNMGGNF

Nucleotide


Download         Length: 1086 bp        

>NTDB_id=450142 FOC63_RS04595 WP_012961328.1 907669..908754(+) (comYB) [Streptococcus gallolyticus strain FDAARGOS_755]
TTGCTAAAGAAAACTTTGAAAGTCACCGACCAGAGTGCTGGAATACAAAAATTGAAAGTCTTGTTAAAGACGGACATATC
ACAGCTGAACAAGCAAAAATCGAAAAAATTGCCATTTAAAAAACAGCGCAAGGTTATTCAACTCTTTAATAATCTTTTTG
AAAGTGGGTTTAATTTAACAGAAATCGTGTCTTTTCTCCGAAGAAGTCAATTGTTGTTAGACATTTATGTTGAGAGGATG
CAAGAAAGTTTGTTAAATGGTGCTAGCCTAGCAACAATGATGGCAGATTTAGGGTTTTCAGACAATATTGTCACACAAAT
TGCTTTGGCTGATGTTCATGGAAACAGTCAGAAAAGTCTGCTGAAGATTGAGTCTTACCTTTCTAGCATGACTGTCGTCA
GAAAAAAGTTAATTGAAGTTGCAACGTATCCATTGATTTTGTTGTTGTTTCTTATTTTGATTATGCTGGGGTTGAAGAAT
TATCTACTGCCACAGTTGGAAAGCCAAAATGTGGCAACGCAGATTATTACGCATTTTCCAACGATTTTTTTGCTAAGTAT
TTTCTCGATTGGAGTGTTGCTTGTTTGTGCGACATTTTATGCTAGGCGTTTATCGCAGATTGATTTATATAGTCGAATAA
GCCGGATTCCACTTGTGGGAAACTATGTTAGGTTATATTTGACAGCTTACTATGCGCGTGAATGGGGAAATTTGATTGGG
CAAGGTATTGAATTAATGGCAATCGTGGGAATCATGCAAAAGCAAAAGTCGCTCTTATTTCAAGAGATTGGAAAGGATAT
GGAAGAAGCGTTGCTTTCAGGGCAAGCTTTTCATCAAAAAGTTCTGGGCTATCCATTCTTTTTGCGAGAATTGAGCCTAA
TGATTGAATATGGTGAGGTCAAATCGAAGCTGGGACGTGAGTTAGACATTTATGCTGAGGAAACATGGCAGAGCTTTTTT
GGCAAATTGACTCAAGCAACACAGCTCATTCAACCACTTGTTTTTGTTTTTGTGGCTTTGATTATTGTGTTAATTTATGT
GGCAATGTTGTTGCCAATGTATCAAAATATGGGAGGAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(232-352)

Type II secretion system (T2SS), protein F (T2SSF)

(47-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

66.772

87.535

0.584
  comYB Streptococcus mutans UA159

66.456

87.535

0.582
  comGB/cglB Streptococcus mitis NCTC 12261

60.472

93.906

0.568
  comYB Streptococcus gordonii str. Challis substr. CH1

60.417

93.075

0.562
  comGB/cglB Streptococcus mitis SK321

57.864

93.352

0.54
  comGB/cglB Streptococcus pneumoniae Rx1

56.973

93.352

0.532
  comGB/cglB Streptococcus pneumoniae D39

56.973

93.352

0.532
  comGB/cglB Streptococcus pneumoniae R6

56.973

93.352

0.532
  comGB/cglB Streptococcus pneumoniae TIGR4

56.973

93.352

0.532
  comGB Lactococcus lactis subsp. cremoris KW2

50.292

94.737

0.476