Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   FOC63_RS04625 Genome accession   NZ_CP054015
Coordinates   910489..911445 (+) Length   318 a.a.
NCBI ID   WP_009853236.1    Uniprot ID   A0A139R3Z2
Organism   Streptococcus gallolyticus strain FDAARGOS_755     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 905489..916445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC63_RS04585 (FOC63_04585) - 906407..906775 (+) 369 WP_009853228.1 DUF1033 family protein -
  FOC63_RS04590 (FOC63_04590) comYA 906846..907787 (+) 942 WP_009853229.1 competence type IV pilus ATPase ComGA Machinery gene
  FOC63_RS04595 (FOC63_04595) comYB 907669..908754 (+) 1086 WP_012961328.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOC63_RS04600 (FOC63_04600) comYC 908754..909047 (+) 294 WP_009853231.1 competence type IV pilus major pilin ComGC Machinery gene
  FOC63_RS04605 (FOC63_04605) comYD 909031..909462 (+) 432 WP_009853232.1 competence type IV pilus minor pilin ComGD Machinery gene
  FOC63_RS04610 (FOC63_04610) comGE 909416..909709 (+) 294 WP_012961329.1 competence type IV pilus minor pilin ComGE -
  FOC63_RS04615 (FOC63_04615) comYF 909663..910130 (+) 468 WP_012961330.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOC63_RS04620 (FOC63_04620) comYG 910102..910416 (+) 315 WP_009853235.1 competence type IV pilus minor pilin ComGG Machinery gene
  FOC63_RS04625 (FOC63_04625) comYH 910489..911445 (+) 957 WP_009853236.1 class I SAM-dependent methyltransferase Machinery gene
  FOC63_RS04630 (FOC63_04630) - 911498..912697 (+) 1200 WP_009853237.1 acetate kinase -
  FOC63_RS04635 (FOC63_04635) - 912859..913059 (+) 201 WP_012961332.1 helix-turn-helix transcriptional regulator -
  FOC63_RS04640 (FOC63_04640) - 913069..913278 (+) 210 WP_009853239.1 hypothetical protein -
  FOC63_RS04645 (FOC63_04645) - 913291..913743 (+) 453 WP_009853240.1 hypothetical protein -
  FOC63_RS04650 (FOC63_04650) - 913755..914393 (+) 639 WP_009853241.1 CPBP family intramembrane glutamic endopeptidase -
  FOC63_RS04655 (FOC63_04655) proC 914453..915223 (-) 771 WP_009853242.1 pyrroline-5-carboxylate reductase -
  FOC63_RS04660 (FOC63_04660) pepA 915284..916351 (-) 1068 WP_009853243.1 glutamyl aminopeptidase -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 36027.96 Da        Isoelectric Point: 4.4127

>NTDB_id=450147 FOC63_RS04625 WP_009853236.1 910489..911445(+) (comYH) [Streptococcus gallolyticus strain FDAARGOS_755]
MNFEKIETAYELILENIQLIENELKTHIYDALIEQNSFYLGAEGASEEVAANNEKLRQLALTKEEWRRAFQFIFIKAGQT
EQLQANHQFTPDAIGFILLFLIENLTDSDKIDLLEIGSGTGNLAQTLLNNSSKELNYLGIEVDDLLIDLSASIAEVMDSD
AQFIQEDAVRPQILKESDVIISDLPVGFYPNDDIAKRYKVASSDEHTYAHHLLMEQSLKYLKKDGIAVFLAPVSLLTSKQ
SDLLKQWLKDYADIIAVITLPESIFGNAANAKSIFVLKKQAAHTPETFVYPLSDLQSREALTDFIRKFQKWKVDNMNF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=450147 FOC63_RS04625 WP_009853236.1 910489..911445(+) (comYH) [Streptococcus gallolyticus strain FDAARGOS_755]
ATGAATTTTGAAAAAATTGAAACAGCCTATGAGCTGATTTTAGAAAATATCCAATTAATTGAAAATGAGTTAAAAACTCA
TATTTATGATGCGCTTATTGAACAGAATTCTTTTTACTTGGGGGCTGAAGGTGCCAGTGAAGAAGTTGCTGCCAACAATG
AGAAACTGCGTCAGCTTGCATTGACCAAAGAAGAGTGGCGTCGAGCTTTCCAATTTATCTTTATCAAAGCTGGTCAAACA
GAGCAGCTGCAAGCCAATCATCAATTTACACCAGATGCTATTGGTTTTATTTTGCTGTTCTTGATTGAAAATCTGACAGA
TTCAGATAAAATTGATCTTTTAGAAATTGGTAGTGGGACAGGAAACCTTGCTCAAACATTGTTAAACAATTCGTCTAAAG
AATTAAATTATCTTGGGATTGAAGTTGACGATTTATTGATTGATTTATCAGCAAGTATTGCAGAAGTGATGGATTCTGAT
GCTCAGTTTATTCAAGAAGATGCTGTGCGTCCACAAATTCTGAAAGAAAGTGATGTGATTATTAGTGATTTGCCAGTTGG
TTTTTATCCTAATGATGACATTGCCAAACGTTATAAAGTGGCAAGTTCTGATGAGCATACCTATGCCCACCATTTGTTAA
TGGAACAATCGTTAAAATATCTCAAAAAAGATGGTATTGCAGTCTTTTTGGCGCCCGTCAGTCTTTTGACAAGTAAGCAA
AGTGATTTATTGAAACAATGGTTGAAAGATTACGCGGATATTATCGCCGTGATTACCTTGCCAGAATCTATTTTTGGTAA
TGCAGCGAATGCAAAATCAATTTTTGTTTTGAAAAAACAGGCTGCGCATACGCCAGAAACCTTTGTTTATCCACTTTCTG
ACTTACAAAGTCGTGAAGCTCTGACTGATTTCATTAGAAAATTTCAAAAATGGAAAGTTGATAATATGAATTTTTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(71-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139R3Z2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

68.987

99.371

0.686
  comYH Streptococcus mutans UA159

68.671

99.371

0.682