Detailed information NTG0450145

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: FOC63_RS04615
• Genome accession: NZ_CP054015
• Coordinates: 909663..910130 (+)
• Length: 155 a.a.
• NCBI ID: WP_012961330.1
• Uniprot ID: A0AA94M0F9
• Organism: Streptococcus gallolyticus strain FDAARGOS_755
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 904663..915130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC63_RS04585 (FOC63_04585)	-	906407..906775 (+)	369	WP_009853228.1	DUF1033 family protein	-
FOC63_RS04590 (FOC63_04590)	comYA	906846..907787 (+)	942	WP_009853229.1	competence type IV pilus ATPase ComGA	Machinery gene
FOC63_RS04595 (FOC63_04595)	comYB	907669..908754 (+)	1086	WP_012961328.1	competence type IV pilus assembly protein ComGB	Machinery gene
FOC63_RS04600 (FOC63_04600)	comYC	908754..909047 (+)	294	WP_009853231.1	competence type IV pilus major pilin ComGC	Machinery gene
FOC63_RS04605 (FOC63_04605)	comYD	909031..909462 (+)	432	WP_009853232.1	competence type IV pilus minor pilin ComGD	Machinery gene
FOC63_RS04610 (FOC63_04610)	comGE	909416..909709 (+)	294	WP_012961329.1	competence type IV pilus minor pilin ComGE	-
FOC63_RS04615 (FOC63_04615)	comYF	909663..910130 (+)	468	WP_012961330.1	competence type IV pilus minor pilin ComGF	Machinery gene
FOC63_RS04620 (FOC63_04620)	comYG	910102..910416 (+)	315	WP_009853235.1	competence type IV pilus minor pilin ComGG	Machinery gene
FOC63_RS04625 (FOC63_04625)	comYH	910489..911445 (+)	957	WP_009853236.1	class I SAM-dependent methyltransferase	Machinery gene
FOC63_RS04630 (FOC63_04630)	-	911498..912697 (+)	1200	WP_009853237.1	acetate kinase	-
FOC63_RS04635 (FOC63_04635)	-	912859..913059 (+)	201	WP_012961332.1	helix-turn-helix transcriptional regulator	-
FOC63_RS04640 (FOC63_04640)	-	913069..913278 (+)	210	WP_009853239.1	hypothetical protein	-
FOC63_RS04645 (FOC63_04645)	-	913291..913743 (+)	453	WP_009853240.1	hypothetical protein	-
FOC63_RS04650 (FOC63_04650)	-	913755..914393 (+)	639	WP_009853241.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 155 a.a.
• Molecular weight: 17515.10 Da
• Isoelectric Point: 9.7290

>NTDB_id=450145 FOC63_RS04615 WP_012961330.1 909663..910130(+) (comYF) [Streptococcus gallolyticus strain FDAARGOS_755]
MFMRGKRKYYTLKKTSLKAFTLIECLVSLLVISGAILVYNALTQSISANVHYLSENQEENWLLFSQQLRAELANCQLDKV
ENNKLYVTKSSQKLAFGQSKADDFRKTNASGQGYQPMIFGVKSSAISRDGQKVTMTLNLENGLERTFVYTFETAS

Nucleotide

• Length: 468 bp

>NTDB_id=450145 FOC63_RS04615 WP_012961330.1 909663..910130(+) (comYF) [Streptococcus gallolyticus strain FDAARGOS_755]
ATGTTTATGAGGGGAAAACGGAAATATTACACGTTAAAAAAGACTAGTTTAAAGGCATTCACCCTCATAGAATGTTTGGT
TTCTTTATTGGTAATTTCGGGTGCTATTCTTGTTTACAATGCCTTAACGCAATCTATTTCTGCAAATGTGCATTATTTGT
CGGAAAATCAAGAGGAAAACTGGCTTTTGTTTTCACAACAGCTGCGTGCGGAGCTTGCCAATTGTCAATTAGATAAGGTT
GAAAATAACAAGCTATATGTGACGAAGTCCAGTCAAAAGTTGGCATTTGGACAGTCAAAGGCTGATGATTTTCGTAAAAC
AAACGCATCTGGTCAAGGCTATCAGCCAATGATATTTGGAGTAAAATCTTCTGCTATTTCTAGAGATGGTCAGAAGGTGA
CAATGACATTAAATTTAGAGAATGGTTTGGAGAGGACATTTGTTTACACTTTTGAAACGGCAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (51-144)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	57.554	89.677	0.516
comYF	Streptococcus mutans UA159	56.835	89.677	0.51
comGF/cglF	Streptococcus pneumoniae Rx1	46.429	90.323	0.419
comGF/cglF	Streptococcus pneumoniae D39	46.429	90.323	0.419
comGF/cglF	Streptococcus pneumoniae R6	46.429	90.323	0.419
comGF/cglF	Streptococcus pneumoniae TIGR4	46.429	90.323	0.419
comGF/cglF	Streptococcus mitis NCTC 12261	45.07	91.613	0.413
comGF/cglF	Streptococcus mitis SK321	44.366	91.613	0.406
comGF	Lactococcus lactis subsp. cremoris KW2	43.478	89.032	0.387