Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   GE021_RS00825 Genome accession   NZ_CP053792
Coordinates   143310..143636 (+) Length   108 a.a.
NCBI ID   WP_125073629.1    Uniprot ID   A0A3P5Y169
Organism   Streptococcus canis strain HL_77_1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 138310..148636
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE021_RS00810 (GE021_000810) - 140947..141312 (+) 366 WP_125073632.1 DUF1033 family protein -
  GE021_RS00815 (GE021_000815) comYA 141399..142340 (+) 942 WP_125073631.1 competence type IV pilus ATPase ComGA Machinery gene
  GE021_RS00820 (GE021_000820) comYB 142273..143307 (+) 1035 WP_172774157.1 competence type IV pilus assembly protein ComGB Machinery gene
  GE021_RS00825 (GE021_000825) comYC 143310..143636 (+) 327 WP_125073629.1 competence type IV pilus major pilin ComGC Machinery gene
  GE021_RS00830 (GE021_000830) comGD 143611..144039 (+) 429 WP_260436826.1 competence type IV pilus minor pilin ComGD -
  GE021_RS00835 (GE021_000835) comGE 144017..144292 (+) 276 WP_125073627.1 competence type IV pilus minor pilin ComGE -
  GE021_RS00840 (GE021_000840) comYF 144273..144713 (+) 441 WP_125073626.1 competence type IV pilus minor pilin ComGF Machinery gene
  GE021_RS00845 (GE021_000845) comGG 144691..145071 (+) 381 WP_125073625.1 competence type IV pilus minor pilin ComGG -
  GE021_RS00850 (GE021_000850) comYH 145121..146074 (+) 954 WP_125073624.1 class I SAM-dependent methyltransferase Machinery gene
  GE021_RS00855 (GE021_000855) - 146133..147329 (+) 1197 WP_093998734.1 acetate kinase -
  GE021_RS00860 (GE021_000860) - 147649..147855 (+) 207 WP_125073623.1 helix-turn-helix transcriptional regulator -
  GE021_RS11180 - 148013..148450 (+) 438 WP_164406320.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12433.41 Da        Isoelectric Point: 9.6760

>NTDB_id=447249 GE021_RS00825 WP_125073629.1 143310..143636(+) (comYC) [Streptococcus canis strain HL_77_1]
MTNQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNTAVVKLVENQAELYELSQGSKPSLSQLKE
DGSITDKQEKAYRDYYGKHKDEVQKLQP

Nucleotide


Download         Length: 327 bp        

>NTDB_id=447249 GE021_RS00825 WP_125073629.1 143310..143636(+) (comYC) [Streptococcus canis strain HL_77_1]
ATGACAAACCAATGGAACAACTTACGACACAAAAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCAAATTTAAGCAAGCAAAAAGACAGGGTTACCGAGACAGGTAATACCGCTG
TTGTTAAATTAGTGGAGAATCAAGCGGAGCTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAACTGAAGGAA
GATGGTAGCATCACTGACAAACAAGAAAAAGCTTATCGCGACTATTATGGCAAACATAAAGATGAAGTTCAAAAATTGCA
ACCTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3P5Y169

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.311

95.37

0.537
  comGC Lactococcus lactis subsp. cremoris KW2

57.292

88.889

0.509
  comGC/cglC Streptococcus mitis SK321

58.696

85.185

0.5
  comGC/cglC Streptococcus mitis NCTC 12261

57.609

85.185

0.491
  comGC/cglC Streptococcus pneumoniae Rx1

53.535

91.667

0.491
  comGC/cglC Streptococcus pneumoniae R6

53.535

91.667

0.491
  comGC/cglC Streptococcus pneumoniae D39

53.535

91.667

0.491
  comGC/cglC Streptococcus pneumoniae TIGR4

56.522

85.185

0.481
  comYC Streptococcus mutans UA140

58.621

80.556

0.472
  comYC Streptococcus mutans UA159

58.621

80.556

0.472
  comYC Streptococcus suis isolate S10

55.556

75

0.417