Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   GE021_RS00815 Genome accession   NZ_CP053792
Coordinates   141399..142340 (+) Length   313 a.a.
NCBI ID   WP_125073631.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 136399..147340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE021_RS00805 (GE021_000805) rpoC 137166..140807 (+) 3642 WP_164406316.1 DNA-directed RNA polymerase subunit beta' -
  GE021_RS00810 (GE021_000810) - 140947..141312 (+) 366 WP_125073632.1 DUF1033 family protein -
  GE021_RS00815 (GE021_000815) comYA 141399..142340 (+) 942 WP_125073631.1 competence type IV pilus ATPase ComGA Machinery gene
  GE021_RS00820 (GE021_000820) comYB 142273..143307 (+) 1035 WP_172774157.1 competence type IV pilus assembly protein ComGB Machinery gene
  GE021_RS00825 (GE021_000825) comYC 143310..143636 (+) 327 WP_125073629.1 competence type IV pilus major pilin ComGC Machinery gene
  GE021_RS00830 (GE021_000830) comGD 143611..144039 (+) 429 WP_260436826.1 competence type IV pilus minor pilin ComGD -
  GE021_RS00835 (GE021_000835) comGE 144017..144292 (+) 276 WP_125073627.1 competence type IV pilus minor pilin ComGE -
  GE021_RS00840 (GE021_000840) comYF 144273..144713 (+) 441 WP_125073626.1 competence type IV pilus minor pilin ComGF Machinery gene
  GE021_RS00845 (GE021_000845) comGG 144691..145071 (+) 381 WP_125073625.1 competence type IV pilus minor pilin ComGG -
  GE021_RS00850 (GE021_000850) comYH 145121..146074 (+) 954 WP_125073624.1 class I SAM-dependent methyltransferase Machinery gene
  GE021_RS00855 (GE021_000855) - 146133..147329 (+) 1197 WP_093998734.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35371.60 Da        Isoelectric Point: 7.2476

>NTDB_id=447247 GE021_RS00815 WP_125073631.1 141399..142340(+) (comYA) [Streptococcus canis strain HL_77_1]
MVQALAKSILKEAEQVQAQDIYILPRADQYELFLRIGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
LDEDTRLSLRLSSVGDYRGQESLVIRLLHHQKKELRYWFDGLTKVASQIGGRGLYLFSGPVGSGKTTLMHQLIADHYQEA
QVISIEDPVEIKNQQALQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTRAELDNCLALIAYQRLLNGGTLIDATQKNFEHYLPDRWNQQIDQLLAAGHLSPKQAMLEKIVQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=447247 GE021_RS00815 WP_125073631.1 141399..142340(+) (comYA) [Streptococcus canis strain HL_77_1]
ATGGTACAAGCATTAGCAAAATCAATTTTGAAAGAAGCAGAGCAAGTTCAGGCTCAAGATATTTATATTCTGCCACGAGC
AGACCAGTACGAGCTCTTTTTAAGAATAGGAGATGAAAGGAGATTAGTAGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGACCGTTGGTGAAAAAAGACGTTGTCAGGTTGGTTCTTGTGATTATGAC
CTTGATGAAGACACGCGATTGTCCTTACGTTTATCCAGTGTTGGAGATTACCGTGGTCAAGAAAGTTTAGTGATTCGTCT
GCTACATCATCAGAAAAAGGAGTTACGTTACTGGTTTGATGGATTAACTAAAGTAGCGAGTCAGATTGGAGGTCGAGGCC
TCTACCTTTTTTCAGGTCCAGTCGGATCAGGGAAAACAACTTTGATGCATCAGCTTATTGCAGATCATTATCAGGAAGCA
CAGGTGATTAGCATTGAAGATCCAGTGGAAATTAAAAACCAGCAGGCCTTACAATTGCAAGTCAATGATGATATTGGCAT
GACTTACGACAATTTAATCAAACTGTCCTTGCGGCATCGACCAGATATTTTGGTCATTGGTGAAATTCGAGATAGTCAGA
CAGCTAGAGCAGTTATTAGAGCTAGTCTAACAGGTGCCATGGTCTTTTCAACAGTGCATGCCAAAAGTATTTCAGGAGTC
TATGCTAGATTGCTAGAACTTGGGGTAACAAGGGCAGAGCTGGATAATTGTTTGGCTTTAATTGCCTACCAACGTTTGCT
TAATGGAGGAACATTGATTGACGCAACTCAAAAAAACTTTGAACACTACCTACCAGACCGGTGGAATCAGCAGATTGATC
AGTTACTTGCAGCAGGACATCTCAGTCCGAAACAAGCAATGCTTGAAAAAATTGTCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

63.023

99.361

0.626
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comYA Streptococcus mutans UA140

62.379

99.361

0.62
  comYA Streptococcus mutans UA159

62.379

99.361

0.62
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.361

0.594
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.164

99.361

0.588
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.164

99.361

0.588
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.164

99.361

0.588
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.164

99.361

0.588
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

39.86

91.374

0.364