Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   HKM25_RS00155 Genome accession   NZ_CP053210
Coordinates   26717..27196 (+) Length   159 a.a.
NCBI ID   WP_000588874.1    Uniprot ID   A0AA44S6A3
Organism   Streptococcus pneumoniae strain 6A-10     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 21717..32196
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKM25_RS00140 (HKM25_26) tilS 22798..24075 (+) 1278 WP_001208993.1 tRNA lysidine(34) synthetase TilS -
  HKM25_RS00145 (HKM25_27) hpt 24079..24621 (+) 543 WP_000892185.1 hypoxanthine phosphoribosyltransferase -
  HKM25_RS00150 (HKM25_28) ftsH 24637..26595 (+) 1959 WP_000744551.1 ATP-dependent zinc metalloprotease FtsH -
  HKM25_RS00155 (HKM25_29) comX/comX2 26717..27196 (+) 480 WP_000588874.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19845.50 Da        Isoelectric Point: 7.3795

>NTDB_id=443415 HKM25_RS00155 WP_000588874.1 26717..27196(+) (comX/comX2) [Streptococcus pneumoniae strain 6A-10]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRK
YDKEPYEEVGELSHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide


Download         Length: 480 bp        

>NTDB_id=443415 HKM25_RS00155 WP_000588874.1 26717..27196(+) (comX/comX2) [Streptococcus pneumoniae strain 6A-10]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
ATCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAAA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGCTCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGTGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

98.742

100

0.987
  comX/comX1 Streptococcus pneumoniae Rx1

98.742

100

0.987
  comX/comX2 Streptococcus pneumoniae D39

98.742

100

0.987
  comX/comX1 Streptococcus pneumoniae D39

98.742

100

0.987
  comX/comX2 Streptococcus pneumoniae R6

98.742

100

0.987
  comX/comX1 Streptococcus pneumoniae R6

98.742

100

0.987
  comX/comX2 Streptococcus pneumoniae TIGR4

98.113

100

0.981
  comX/comX1 Streptococcus pneumoniae TIGR4

98.113

100

0.981
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

91.195

100

0.912
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

91.195

100

0.912
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

89.308

100

0.893
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

87.975

99.371

0.874
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comX/sigX Streptococcus suis D9

47.02

94.969

0.447
  comX/sigX Streptococcus suis isolate S10

47.02

94.969

0.447
  comX/sigX Streptococcus suis P1/7

47.02

94.969

0.447
  comX/sigX Streptococcus mutans UA159

44.667

94.34

0.421
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

94.34

0.377