Detailed information NTG0422576

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: G3T51_RS07845
• Genome accession: NZ_CP048732
• Coordinates: 1578769..1579608 (+)
• Length: 279 a.a.
• NCBI ID: WP_260440326.1
• Uniprot ID: -
• Organism: Mammaliicoccus sciuri strain NWAF26
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1573769..1584608

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G3T51_RS07805	-	1573855..1574415 (+)	561	WP_152291611.1	5-formyltetrahydrofolate cyclo-ligase	-
G3T51_RS07810	-	1574408..1575856 (+)	1449	WP_048539718.1	rhomboid family intramembrane serine protease	-
G3T51_RS07815	-	1575861..1576052 (+)	192	WP_078099923.1	YqgQ family protein	-
G3T51_RS07820	-	1576049..1577020 (+)	972	WP_048539719.1	ROK family glucokinase	-
G3T51_RS07825	-	1577020..1577334 (+)	315	WP_185160422.1	MTH1187 family thiamine-binding protein	-
G3T51_RS07830	-	1577363..1577602 (-)	240	WP_016911885.1	DUF2759 domain-containing protein	-
G3T51_RS07835	-	1577700..1578332 (+)	633	WP_075577989.1	MBL fold metallo-hydrolase	-
G3T51_RS07840	-	1578367..1578615 (-)	249	WP_025904960.1	DUF2626 family protein	-
G3T51_RS07845	comGA	1578769..1579608 (+)	840	WP_260440326.1	competence type IV pilus ATPase ComGA	Machinery gene
G3T51_RS07850	comGB	1579660..1580700 (+)	1041	WP_107602469.1	competence type IV pilus assembly protein ComGB	-
G3T51_RS07855	comGC	1580715..1581032 (+)	318	WP_152291612.1	competence type IV pilus major pilin ComGC	Machinery gene
G3T51_RS07860	comGD	1581010..1581459 (+)	450	WP_048539818.1	competence type IV pilus minor pilin ComGD	-
G3T51_RS07865	comGE	1581443..1581724 (+)	282	WP_048539723.1	competence type IV pilus minor pilin ComGE	-
G3T51_RS07870	-	1581738..1582133 (+)	396	WP_242453055.1	competence type IV pilus minor pilin ComGF	-
G3T51_RS07875	-	1582368..1582856 (+)	489	WP_048539725.1	shikimate kinase	-
G3T51_RS07880	gcvT	1583049..1584137 (+)	1089	WP_152292031.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31910.68 Da
• Isoelectric Point: 6.7663

>NTDB_id=422576 G3T51_RS07845 WP_260440326.1 1578769..1579608(+) (comGA) [Mammaliicoccus sciuri strain NWAF26]
MEKLFKSIINDAVNSNASDIHFVPLNDDKVFVQMRINGDNTPYDLDLDFKLYSRLLIYMKFIAHLDVSERNKAQSGQYLY
EHDIHYYLRISTIPISLGIESCSIRITPQHFNQSQVKSEDQFYNVLQNRMYQSEGLFLFTGPTGSGKTTLMYELMYALKR
EKNKHIITIEDPVEQTLNGIVQVSVNEKANITYQQSFKAILRCDPDVIMIGEIRDDVTAKQVIQASLSGHLVLSTMHASD
TIGAIHRLIELGVSVEQIKQGISCITNQRLVKKMMKQEL

Nucleotide

• Length: 840 bp

>NTDB_id=422576 G3T51_RS07845 WP_260440326.1 1578769..1579608(+) (comGA) [Mammaliicoccus sciuri strain NWAF26]
ATGGAGAAATTATTTAAGTCAATTATTAACGATGCTGTCAATTCAAATGCGAGTGATATTCACTTTGTACCTTTAAATGA
TGATAAAGTCTTTGTTCAAATGAGGATAAATGGTGATAATACACCTTATGATTTAGATCTAGACTTTAAATTGTATAGTA
GGCTACTCATTTATATGAAATTTATCGCTCATCTTGATGTAAGTGAACGTAATAAAGCACAAAGCGGTCAATATTTATAT
GAACATGACATTCATTACTACTTAAGAATTTCTACGATACCTATCAGTTTAGGAATAGAATCTTGTTCCATTAGAATTAC
CCCTCAACATTTTAATCAATCACAAGTGAAATCAGAAGATCAATTTTATAACGTTTTACAAAATAGAATGTATCAATCAG
AAGGGCTATTTCTATTTACGGGTCCAACTGGATCAGGTAAGACGACATTAATGTATGAATTGATGTACGCTTTAAAGAGA
GAAAAGAACAAACATATTATTACGATTGAAGACCCTGTAGAACAAACGTTAAATGGCATCGTTCAAGTTTCAGTCAATGA
AAAAGCTAACATAACTTATCAACAATCCTTTAAAGCCATTTTAAGATGTGATCCTGACGTTATAATGATTGGAGAGATAA
GAGACGATGTTACTGCTAAGCAAGTTATTCAAGCTAGTTTAAGTGGTCATTTAGTACTTTCAACAATGCACGCGAGTGAT
ACAATTGGGGCAATCCACCGACTAATAGAACTAGGTGTATCAGTCGAACAAATTAAACAAGGTATTTCATGTATTACAAA
CCAACGTCTTGTGAAAAAAATGATGAAACAAGAACTTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus N315	53.237	99.642	0.53
comGA	Staphylococcus aureus MW2	53.237	99.642	0.53
comGA	Bacillus subtilis subsp. subtilis str. 168	40.794	99.283	0.405
pilB	Glaesserella parasuis strain SC1401	37.5	100	0.376
comYA	Streptococcus mutans UA159	37.455	98.566	0.369
comYA	Streptococcus mutans UA140	37.455	98.566	0.369
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	37.868	97.491	0.369
comYA	Streptococcus gordonii str. Challis substr. CH1	37.868	97.491	0.369
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	37.729	97.849	0.369
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	37.729	97.849	0.369
comGA/cglA/cilD	Streptococcus pneumoniae D39	37.729	97.849	0.369
comGA/cglA/cilD	Streptococcus pneumoniae R6	37.729	97.849	0.369
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	36.691	99.642	0.366
pilB	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	36.042	100	0.366
pilF	Thermus thermophilus HB27	36.201	100	0.362
pilB	Haemophilus influenzae Rd KW20	36.462	99.283	0.362