Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SALIVB_RS09595 Genome accession   NC_015760
Coordinates   2073004..2073945 (-) Length   313 a.a.
NCBI ID   WP_013991268.1    Uniprot ID   -
Organism   Streptococcus salivarius CCHSS3     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2068004..2078945
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVB_RS09555 (SALIVB_1994) - 2068079..2069272 (-) 1194 WP_003095894.1 acetate kinase -
  SALIVB_RS09560 (SALIVB_1995) comYH 2069329..2070285 (-) 957 WP_013991262.1 class I SAM-dependent methyltransferase Machinery gene
  SALIVB_RS09565 (SALIVB_1996) comGG 2070330..2070647 (-) 318 WP_041817287.1 competence type IV pilus minor pilin ComGG -
  SALIVB_RS09570 (SALIVB_1997) comYF 2070625..2071062 (-) 438 WP_013991264.1 competence type IV pilus minor pilin ComGF Machinery gene
  SALIVB_RS09575 (SALIVB_1998) comGE 2071049..2071279 (-) 231 WP_013991265.1 competence type IV pilus minor pilin ComGE -
  SALIVB_RS09580 (SALIVB_1999) comYD 2071311..2071739 (-) 429 WP_014632541.1 competence type IV pilus minor pilin ComGD Machinery gene
  SALIVB_RS09585 (SALIVB_2000) comYC 2071699..2072013 (-) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  SALIVB_RS09590 (SALIVB_2001) comYB 2072022..2073122 (-) 1101 WP_155114411.1 competence type IV pilus assembly protein ComGB Machinery gene
  SALIVB_RS09595 (SALIVB_2002) comYA 2073004..2073945 (-) 942 WP_013991268.1 competence type IV pilus ATPase ComGA Machinery gene
  SALIVB_RS09600 (SALIVB_2003) - 2074025..2074387 (-) 363 WP_002887019.1 DUF1033 family protein -
  SALIVB_RS09605 (SALIVB_2004) rpoC 2074550..2078188 (-) 3639 WP_013991269.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35226.26 Da        Isoelectric Point: 5.4492

>NTDB_id=41853 SALIVB_RS09595 WP_013991268.1 2073004..2073945(-) (comYA) [Streptococcus salivarius CCHSS3]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQSVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSISWNQQLEGLVKQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=41853 SALIVB_RS09595 WP_013991268.1 2073004..2073945(-) (comYA) [Streptococcus salivarius CCHSS3]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTACGAGCTCTATATGCGAGTTGGCCAGGAGAGAAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGTGTTTCTCTGCGTTTGTCTACCGTTGGGGATTATCGTGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGAATTAGTGTACTGGAATCAAGGAATCCAGCCTATTATGGATGCTTTGGATTATCGTGGCT
TATATCTCTTTGCAGGTCCCGTTGGTTCTGGAAAGACTACGCTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTGATTTCGATTGAGGATCCTGTGGAAATTAAACAGGATAATGTTTTGCAACTCCAGGTGAATCAAGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTGCGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACGGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTTGGTGTAGATAAGTCTGAGTTGGATAATGCCCTTCAAGGGATTGCCTACATGCGTCTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAATCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTAAACAAGGATATCTCACGGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

65.176

100

0.652
  comYA Streptococcus mutans UA140

65.176

100

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.63

99.361

0.642
  comYA Streptococcus gordonii str. Challis substr. CH1

62.62

100

0.626
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361

Multiple sequence alignment