Detailed information
Bioinformatically predicted
Overview
| Name | comGC/cglC | Type | Machinery gene |
| Locus tag | GL183_RS01050 | Genome accession | NZ_CP046355 |
| Coordinates | 208687..209013 (+) | Length | 108 a.a. |
| NCBI ID | WP_000738625.1 | Uniprot ID | - |
| Organism | Streptococcus pneumoniae strain 475 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 203687..214013
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GL183_RS01025 (GL183_01040) | nagA | 203817..204968 (+) | 1152 | WP_001134457.1 | N-acetylglucosamine-6-phosphate deacetylase | - |
| GL183_RS01030 (GL183_01045) | - | 205131..206189 (+) | 1059 | WP_000649471.1 | zinc-dependent alcohol dehydrogenase family protein | - |
| GL183_RS01035 (GL183_01050) | - | 206340..206705 (+) | 366 | WP_000286415.1 | DUF1033 family protein | - |
| GL183_RS01040 (GL183_01055) | comGA/cglA/cilD | 206780..207721 (+) | 942 | WP_000249555.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| GL183_RS01045 (GL183_01060) | comGB/cglB | 207669..208685 (+) | 1017 | WP_074017570.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| GL183_RS01050 (GL183_01065) | comGC/cglC | 208687..209013 (+) | 327 | WP_000738625.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| GL183_RS01055 (GL183_01070) | comGD/cglD | 209006..209410 (+) | 405 | WP_000588030.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| GL183_RS01060 (GL183_01075) | comGE/cglE | 209373..209675 (+) | 303 | WP_000413382.1 | competence type IV pilus minor pilin ComGE | Machinery gene |
| GL183_RS01065 (GL183_01080) | comGF/cglF | 209638..210099 (+) | 462 | WP_000250539.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| GL183_RS01070 (GL183_01085) | comGG/cglG | 210077..210523 (+) | 447 | WP_001811371.1 | competence type IV pilus minor pilin ComGG | Machinery gene |
| GL183_RS01075 (GL183_01090) | - | 210626..211213 (+) | 588 | WP_000679779.1 | class I SAM-dependent methyltransferase | - |
| GL183_RS01080 (GL183_01100) | comYH | 211274..212227 (+) | 954 | WP_000345122.1 | class I SAM-dependent methyltransferase | Machinery gene |
| GL183_RS01085 (GL183_01105) | - | 212278..213468 (+) | 1191 | WP_000167765.1 | acetate kinase | - |
| GL183_RS11615 | - | 213469..213600 (+) | 132 | WP_000768904.1 | hypothetical protein | - |
| GL183_RS01090 (GL183_01110) | rnpA | 213617..213988 (+) | 372 | WP_000739247.1 | ribonuclease P protein component | - |
Sequence
Protein
Download Length: 108 a.a. Molecular weight: 12143.28 Da Isoelectric Point: 10.0055
>NTDB_id=403009 GL183_RS01050 WP_000738625.1 208687..209013(+) (comGC/cglC) [Streptococcus pneumoniae strain 475]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQG
DGRITEEQVKAYNEYYTKNGGANRKVND
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQG
DGRITEEQVKAYNEYYTKNGGANRKVND
Nucleotide
Download Length: 327 bp
>NTDB_id=403009 GL183_RS01050 WP_000738625.1 208687..209013(+) (comGC/cglC) [Streptococcus pneumoniae strain 475]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTAGTAGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGATAAAAATGAAGATGCTACTCTGAGCAAGTTACAAGGA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTAGTAGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGATAAAAATGAAGATGCTACTCTGAGCAAGTTACAAGGA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGC/cglC | Streptococcus mitis SK321 |
95.37 |
100 |
0.954 |
| comGC/cglC | Streptococcus pneumoniae Rx1 |
92.593 |
100 |
0.926 |
| comGC/cglC | Streptococcus pneumoniae D39 |
92.593 |
100 |
0.926 |
| comGC/cglC | Streptococcus pneumoniae R6 |
92.593 |
100 |
0.926 |
| comGC/cglC | Streptococcus pneumoniae TIGR4 |
92.593 |
100 |
0.926 |
| comGC/cglC | Streptococcus mitis NCTC 12261 |
92.857 |
90.741 |
0.843 |
| comYC | Streptococcus gordonii str. Challis substr. CH1 |
67.961 |
95.37 |
0.648 |
| comYC | Streptococcus mutans UA140 |
62.745 |
94.444 |
0.593 |
| comYC | Streptococcus mutans UA159 |
62.745 |
94.444 |
0.593 |
| comGC | Lactococcus lactis subsp. cremoris KW2 |
56.863 |
94.444 |
0.537 |
| comYC | Streptococcus suis isolate S10 |
64.773 |
81.481 |
0.528 |
| comGC | Staphylococcus aureus MW2 |
47.674 |
79.63 |
0.38 |
| comGC | Staphylococcus aureus N315 |
47.674 |
79.63 |
0.38 |