Detailed information NTG0375221

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: FPT06_RS04445
• Genome accession: NZ_CP041994
• Coordinates: 904486..904767 (-)
• Length: 93 a.a.
• NCBI ID: WP_009909092.1
• Uniprot ID: A0A116MYU4
• Organism: Streptococcus suis strain INT-01
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 899486..909767

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FPT06_RS04405 (FPT06_04405)	-	899866..900462 (-)	597	WP_009909104.1	folate family ECF transporter S component	-
FPT06_RS04415 (FPT06_04415)	-	900777..901964 (-)	1188	WP_013730078.1	acetate kinase	-
FPT06_RS04420 (FPT06_04420)	comYH	902014..902967 (-)	954	WP_013730077.1	class I SAM-dependent methyltransferase	Machinery gene
FPT06_RS04425 (FPT06_04425)	comGG	903024..903434 (-)	411	WP_009909099.1	competence type IV pilus minor pilin ComGG	-
FPT06_RS04430 (FPT06_04430)	comGF/cglF	903412..903846 (-)	435	WP_009909097.1	competence type IV pilus minor pilin ComGF	Machinery gene
FPT06_RS04435 (FPT06_04435)	comYE	903833..904126 (-)	294	WP_024390433.1	competence type IV pilus minor pilin ComGE	Machinery gene
FPT06_RS04440 (FPT06_04440)	comGD	904098..904505 (-)	408	WP_009909093.1	competence type IV pilus minor pilin ComGD	-
FPT06_RS04445 (FPT06_04445)	comYC	904486..904767 (-)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
FPT06_RS04450 (FPT06_04450)	comYB	904769..905806 (-)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
FPT06_RS04455 (FPT06_04455)	comYA	905718..906668 (-)	951	WP_013730075.1	competence type IV pilus ATPase ComGA	Machinery gene
FPT06_RS04460 (FPT06_04460)	-	906754..907704 (+)	951	WP_002936565.1	S66 peptidase family protein	-
FPT06_RS04465 (FPT06_04465)	-	907739..908104 (-)	366	WP_002936568.1	DUF1033 family protein	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10320.28 Da
• Isoelectric Point: 8.4284

>NTDB_id=375221 FPT06_RS04445 WP_009909092.1 904486..904767(-) (comYC) [Streptococcus suis strain INT-01]
MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEHDKEATVADLQAAGYI
TEKQAKQYAAAKK

Nucleotide

• Length: 282 bp

>NTDB_id=375221 FPT06_RS04445 WP_009909092.1 904486..904767(-) (comYC) [Streptococcus suis strain INT-01]
ATGAAAAAATTAGTTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCCTTTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCTGTTGTCAAAGTAG
TGGAGAGCCAGATGGAGCTCTATGAATTGGAACATGACAAGGAAGCAACGGTGGCAGACTTGCAGGCAGCTGGCTACATC
ACTGAAAAACAAGCAAAACAGTATGCTGCGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A116MYU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	96.774	100	0.968
comGC/cglC	Streptococcus mitis SK321	67.059	91.398	0.613
comGC/cglC	Streptococcus mitis NCTC 12261	67.059	91.398	0.613
comYC	Streptococcus gordonii str. Challis substr. CH1	62.637	97.849	0.613
comGC/cglC	Streptococcus pneumoniae R6	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae D39	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae TIGR4	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae Rx1	69.136	87.097	0.602
comYC	Streptococcus mutans UA140	60.227	94.624	0.57
comYC	Streptococcus mutans UA159	60.227	94.624	0.57
comGC	Lactococcus lactis subsp. cremoris KW2	57.955	94.624	0.548
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Bacillus subtilis subsp. subtilis str. 168	49.333	80.645	0.398