Detailed information NTG0362614

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: FD735_RS00855
• Genome accession: NZ_CP040231
• Coordinates: 150797..151120 (+)
• Length: 107 a.a.
• NCBI ID: WP_061421834.1
• Uniprot ID: A0A139Q3A2
• Organism: Streptococcus sp. 1643
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 145797..156120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FD735_RS00835 (FD735_00835)	nagA	147160..148311 (+)	1152	WP_001134437.1	N-acetylglucosamine-6-phosphate deacetylase	-
FD735_RS00840 (FD735_00840)	-	148463..148828 (+)	366	WP_061421836.1	DUF1033 family protein	-
FD735_RS00845 (FD735_00845)	comGA/cglA/cilD	148890..149831 (+)	942	WP_061421835.1	competence type IV pilus ATPase ComGA	Machinery gene
FD735_RS00850 (FD735_00850)	comGB/cglB	149779..150795 (+)	1017	WP_081102569.1	competence type IV pilus assembly protein ComGB	Machinery gene
FD735_RS00855 (FD735_00855)	comGC/cglC	150797..151120 (+)	324	WP_061421834.1	competence type IV pilus major pilin ComGC	Machinery gene
FD735_RS00860 (FD735_00860)	comGD/cglD	151083..151517 (+)	435	WP_176553041.1	competence type IV pilus minor pilin ComGD	Machinery gene
FD735_RS00865 (FD735_00865)	comGE/cglE	151480..151782 (+)	303	WP_139658261.1	competence type IV pilus minor pilin ComGE	Machinery gene
FD735_RS00870 (FD735_00870)	comGF/cglF	151745..152206 (+)	462	WP_139658262.1	competence type IV pilus minor pilin ComGF	Machinery gene
FD735_RS00875 (FD735_00875)	comGG/cglG	152184..152597 (+)	414	WP_139658263.1	competence type IV pilus minor pilin ComGG	Machinery gene
FD735_RS00880 (FD735_00880)	-	152630..153220 (+)	591	WP_176553042.1	class I SAM-dependent methyltransferase	-
FD735_RS00885 (FD735_00885)	comYH	153279..154232 (+)	954	WP_139658264.1	class I SAM-dependent methyltransferase	Machinery gene
FD735_RS00890 (FD735_00890)	-	154283..155473 (+)	1191	WP_139658265.1	acetate kinase	-
FD735_RS00895 (FD735_00895)	rnpA	155623..155994 (+)	372	WP_000748120.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 11850.02 Da
• Isoelectric Point: 10.1648

>NTDB_id=362614 FD735_RS00855 WP_061421834.1 150797..151120(+) (comGC/cglC) [Streptococcus sp. 1643]
MKKLMTKLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVDDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITAEQAKAYKDYHAKQKTSQTVAD

Nucleotide

• Length: 324 bp

>NTDB_id=362614 FD735_RS00855 WP_061421834.1 150797..151120(+) (comGC/cglC) [Streptococcus sp. 1643]
ATGAAAAAACTCATGACAAAATTAAAAAAAGCCAAGGTTAAAGCTTTCACTCTGGTAGAGATGTTAGTCGTCTTGCTCAT
CATCAGCGTTCTTCTCTTGCTCTTTGTACCCAATTTGACCAAGCAAAAGGATGCCGTTGATGACAAAGGAAAAGCTGCTG
TTGTCAAGGTTGTGGAAAGCCAGGCAGAGCTCTATAGTCTGGACAAGAATGAAGATGCCAGCCTCAGCAAATTACAAGCG
GACGGTCGTATCACAGCTGAGCAAGCTAAAGCTTATAAAGACTACCATGCAAAACAAAAAACAAGTCAAACTGTTGCAGA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

3D structure

• AlphaFold DB: A0A139Q3A2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	93.458	100	0.935
comGC/cglC	Streptococcus mitis SK321	90.909	92.523	0.841
comGC/cglC	Streptococcus pneumoniae R6	88.889	92.523	0.822
comGC/cglC	Streptococcus pneumoniae Rx1	88.889	92.523	0.822
comGC/cglC	Streptococcus pneumoniae D39	88.889	92.523	0.822
comGC/cglC	Streptococcus pneumoniae TIGR4	87.879	92.523	0.813
comYC	Streptococcus gordonii str. Challis substr. CH1	68.571	98.131	0.673
comYC	Streptococcus mutans UA140	70.103	90.654	0.636
comYC	Streptococcus mutans UA159	70.103	90.654	0.636
comYC	Streptococcus suis isolate S10	68.182	82.243	0.561
comGC	Lactococcus lactis subsp. cremoris KW2	56.863	95.327	0.542