Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   FD735_RS00885 Genome accession   NZ_CP040231
Coordinates   153279..154232 (+) Length   317 a.a.
NCBI ID   WP_139658264.1    Uniprot ID   A0A5B7Y6M6
Organism   Streptococcus sp. 1643     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 148279..159232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD735_RS00840 (FD735_00840) - 148463..148828 (+) 366 WP_061421836.1 DUF1033 family protein -
  FD735_RS00845 (FD735_00845) comGA/cglA/cilD 148890..149831 (+) 942 WP_061421835.1 competence type IV pilus ATPase ComGA Machinery gene
  FD735_RS00850 (FD735_00850) comGB/cglB 149779..150795 (+) 1017 WP_081102569.1 competence type IV pilus assembly protein ComGB Machinery gene
  FD735_RS00855 (FD735_00855) comGC/cglC 150797..151120 (+) 324 WP_061421834.1 competence type IV pilus major pilin ComGC Machinery gene
  FD735_RS00860 (FD735_00860) comGD/cglD 151083..151517 (+) 435 WP_176553041.1 competence type IV pilus minor pilin ComGD Machinery gene
  FD735_RS00865 (FD735_00865) comGE/cglE 151480..151782 (+) 303 WP_139658261.1 competence type IV pilus minor pilin ComGE Machinery gene
  FD735_RS00870 (FD735_00870) comGF/cglF 151745..152206 (+) 462 WP_139658262.1 competence type IV pilus minor pilin ComGF Machinery gene
  FD735_RS00875 (FD735_00875) comGG/cglG 152184..152597 (+) 414 WP_139658263.1 competence type IV pilus minor pilin ComGG Machinery gene
  FD735_RS00880 (FD735_00880) - 152630..153220 (+) 591 WP_176553042.1 class I SAM-dependent methyltransferase -
  FD735_RS00885 (FD735_00885) comYH 153279..154232 (+) 954 WP_139658264.1 class I SAM-dependent methyltransferase Machinery gene
  FD735_RS00890 (FD735_00890) - 154283..155473 (+) 1191 WP_139658265.1 acetate kinase -
  FD735_RS00895 (FD735_00895) rnpA 155623..155994 (+) 372 WP_000748120.1 ribonuclease P protein component -
  FD735_RS00900 (FD735_00900) - 155969..156796 (+) 828 WP_176553043.1 membrane protein insertase YidC -
  FD735_RS00905 (FD735_00905) jag 156811..157797 (+) 987 WP_139658267.1 RNA-binding cell elongation regulator Jag/EloR -
  FD735_RS00910 (FD735_00910) - 157853..158476 (+) 624 WP_139658268.1 ribonuclease P -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35552.55 Da        Isoelectric Point: 4.0946

>NTDB_id=362619 FD735_RS00885 WP_139658264.1 153279..154232(+) (comYH) [Streptococcus sp. 1643]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELEQVKENNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVLVVEELFEQEEISILEIGSGMGILGATFLTSLSKKVDYLGIEVDDLLIDLAASMSDVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDNAIASRYQVASSQEYTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKGWLKDEVSLAAIIALPEDIFSTASQAKSIFVLQKKIDKEIEPFVYPLTSLQDPSVLLTFKENFQNWSKGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=362619 FD735_RS00885 WP_139658264.1 153279..154232(+) (comYH) [Streptococcus sp. 1643]
ATGGATTTTGAAAAAATTGAACAAGCTTATACGTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGATGCCTTAGTAGAGCAAAATAGTATCTACCTAGATGGCGAGACAGAGCTGGAGCAGGTCAAGGAGAACAATC
AAGCCCTTAAGCGCTTAGCGCTTCGCAAGGAAGAGTGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCAGGACAAACG
GAACCTTTACAGGCCAATCACCAGTTTACACCAGATGCCATTGCCCTCCTCTTGGTACTTGTTGTAGAAGAGTTGTTTGA
ACAAGAGGAAATTAGCATCCTCGAAATAGGTTCTGGTATGGGGATTTTGGGGGCTACTTTCTTGACTTCTCTCTCTAAAA
AAGTAGATTACTTGGGAATCGAAGTGGATGATTTGCTGATTGATTTGGCAGCAAGTATGTCAGATGTGATTGGTTTACAG
GCTGGTTTTGTTCAAGGAGACGCCGTTCGTCCGCAAATGCTTAAAGAAAGCGACGTGGTCATCAGCGACTTGCCTGTAGG
CTATTACCCAGACAATGCCATCGCTTCTCGCTATCAAGTGGCTTCTAGTCAAGAGTATACCTATGCCCACCATTTGCTAA
TGGAACAAGGCCTCAAGTACCTTAAGTCAGATGGCTATGCAATTTTTCTAGCTCCGAGTGATTTATTGACCAGTCCTCAA
AGTGATTTATTAAAAGGGTGGCTCAAAGACGAAGTGAGTCTGGCTGCTATCATCGCTCTGCCAGAGGATATTTTCTCAAC
TGCAAGCCAAGCTAAAAGTATTTTTGTCTTACAGAAGAAAATAGACAAGGAAATAGAACCCTTTGTCTACCCTCTTACTA
GCTTGCAAGATCCGTCAGTTTTGTTGACCTTTAAAGAAAATTTTCAAAATTGGAGCAAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5B7Y6M6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

57.556

98.107

0.565
  comYH Streptococcus mutans UA159

57.235

98.107

0.562

Multiple sequence alignment