Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   FD735_RS00865 Genome accession   NZ_CP040231
Coordinates   151480..151782 (+) Length   100 a.a.
NCBI ID   WP_139658261.1    Uniprot ID   -
Organism   Streptococcus sp. 1643     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 146480..156782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD735_RS00835 (FD735_00835) nagA 147160..148311 (+) 1152 WP_001134437.1 N-acetylglucosamine-6-phosphate deacetylase -
  FD735_RS00840 (FD735_00840) - 148463..148828 (+) 366 WP_061421836.1 DUF1033 family protein -
  FD735_RS00845 (FD735_00845) comGA/cglA/cilD 148890..149831 (+) 942 WP_061421835.1 competence type IV pilus ATPase ComGA Machinery gene
  FD735_RS00850 (FD735_00850) comGB/cglB 149779..150795 (+) 1017 WP_081102569.1 competence type IV pilus assembly protein ComGB Machinery gene
  FD735_RS00855 (FD735_00855) comGC/cglC 150797..151120 (+) 324 WP_061421834.1 competence type IV pilus major pilin ComGC Machinery gene
  FD735_RS00860 (FD735_00860) comGD/cglD 151083..151517 (+) 435 WP_176553041.1 competence type IV pilus minor pilin ComGD Machinery gene
  FD735_RS00865 (FD735_00865) comGE/cglE 151480..151782 (+) 303 WP_139658261.1 competence type IV pilus minor pilin ComGE Machinery gene
  FD735_RS00870 (FD735_00870) comGF/cglF 151745..152206 (+) 462 WP_139658262.1 competence type IV pilus minor pilin ComGF Machinery gene
  FD735_RS00875 (FD735_00875) comGG/cglG 152184..152597 (+) 414 WP_139658263.1 competence type IV pilus minor pilin ComGG Machinery gene
  FD735_RS00880 (FD735_00880) - 152630..153220 (+) 591 WP_176553042.1 class I SAM-dependent methyltransferase -
  FD735_RS00885 (FD735_00885) comYH 153279..154232 (+) 954 WP_139658264.1 class I SAM-dependent methyltransferase Machinery gene
  FD735_RS00890 (FD735_00890) - 154283..155473 (+) 1191 WP_139658265.1 acetate kinase -
  FD735_RS00895 (FD735_00895) rnpA 155623..155994 (+) 372 WP_000748120.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11211.16 Da        Isoelectric Point: 7.0157

>NTDB_id=362616 FD735_RS00865 WP_139658261.1 151480..151782(+) (comGE/cglE) [Streptococcus sp. 1643]
MEKLNVLRKQKIKAVILLEAVVALAVFASIATLLLGQIQKNRQEEVEILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGVEVYHGSEKLLDLKEQ

Nucleotide


Download         Length: 303 bp        

>NTDB_id=362616 FD735_RS00865 WP_139658261.1 151480..151782(+) (comGE/cglE) [Streptococcus sp. 1643]
ATGGAAAAATTAAACGTATTAAGGAAACAAAAAATTAAGGCAGTAATCTTACTAGAAGCAGTAGTAGCTTTGGCTGTGTT
TGCCAGCATTGCGACCCTTCTTTTGGGACAAATCCAGAAAAATAGGCAGGAAGAGGTAGAAATCTTGCAAAAGGAAGAAG
TCTTGCGTGTGGCGAAGATGGCTCTGCAAACAGGGCAAAATCAGGTAAACATAAATGGAGTGGAGATTCAGGTGTTTTCT
AGTGAAAAAGGAGTGGAGGTCTATCATGGTTCAGAGAAGTTACTCGACCTTAAAGAGCAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae Rx1

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae D39

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae R6

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae TIGR4

89.899

99

0.89
  comGE/cglE Streptococcus mitis SK321

88.889

99

0.88
  comYE Streptococcus mutans UA140

42.857

91

0.39
  comYE Streptococcus mutans UA159

42.857

91

0.39

Multiple sequence alignment