Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   E8M06_RS00765 Genome accession   NZ_CP039462
Coordinates   123846..124796 (+) Length   316 a.a.
NCBI ID   WP_136581015.1    Uniprot ID   -
Organism   Streptococcus suis strain WUSS351     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 118846..129796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M06_RS00755 (E8M06_00755) - 122410..122775 (+) 366 WP_024395451.1 DUF1033 family protein -
  E8M06_RS00760 (E8M06_00760) - 122810..123760 (-) 951 WP_136581014.1 S66 peptidase family protein -
  E8M06_RS00765 (E8M06_00765) comYA 123846..124796 (+) 951 WP_136581015.1 competence type IV pilus ATPase ComGA Machinery gene
  E8M06_RS00770 (E8M06_00770) comYB 124708..125745 (+) 1038 WP_247904444.1 competence type IV pilus assembly protein ComGB Machinery gene
  E8M06_RS00775 (E8M06_00775) comYC 125747..126028 (+) 282 WP_105145695.1 competence type IV pilus major pilin ComGC Machinery gene
  E8M06_RS00780 (E8M06_00780) comGD 126009..126416 (+) 408 WP_136581016.1 competence type IV pilus minor pilin ComGD -
  E8M06_RS00785 (E8M06_00785) comYE 126388..126681 (+) 294 WP_044680789.1 competence type IV pilus minor pilin ComGE Machinery gene
  E8M06_RS00790 (E8M06_00790) comGF/cglF 126668..127102 (+) 435 WP_044687018.1 competence type IV pilus minor pilin ComGF Machinery gene
  E8M06_RS00795 (E8M06_00795) comGG 127080..127490 (+) 411 WP_024395444.1 competence type IV pilus minor pilin ComGG -
  E8M06_RS00800 (E8M06_00800) comYH 127547..128500 (+) 954 WP_044778430.1 class I SAM-dependent methyltransferase Machinery gene
  E8M06_RS00805 (E8M06_00805) - 128550..129737 (+) 1188 WP_014637319.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35338.27 Da        Isoelectric Point: 5.9417

>NTDB_id=358827 E8M06_RS00765 WP_136581015.1 123846..124796(+) (comYA) [Streptococcus suis strain WUSS351]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDVAEEEVIAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGGISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQDGMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADKWNEQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=358827 E8M06_RS00765 WP_136581015.1 123846..124796(+) (comYA) [Streptococcus suis strain WUSS351]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTATCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACGTGGCTGAGGAAGAAGTAATAGCCA
TCATTAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGCGGAGGGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACGCTCATGTATCATCTTGCCAGGCTGAAGTTTCCAGACAAGCAA
ATTTTGACCATTGAAGATCCTGTAGAAATCAAGCAGGACGGGATGTTGCAGCTCCAGCTCAATGAAGCCATCGGAGCTAC
CTACGATAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTCCATGCAAGGTCTATTTCAGGTGTCTAT
GCCCGTATGTTGGAACTGGGGGTCAGTCCTGAGGAGCTAAACAATGCCCTTCAAGGCATTGCCTATCAACGATTGATTGG
GGGAGGAGGTGTGGTAGATTTTGCAAAAGGAAATTACCAAAACCATTCCGCAGACAAGTGGAATGAACAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

69.231

98.734

0.684
  comYA Streptococcus mutans UA140

69.231

98.734

0.684
  comYA Streptococcus gordonii str. Challis substr. CH1

68.065

98.101

0.668
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

98.418

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.161

98.101

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.943

100

0.541

Multiple sequence alignment