Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   E8M06_RS00770 Genome accession   NZ_CP039462
Coordinates   124708..125745 (+) Length   345 a.a.
NCBI ID   WP_247904444.1    Uniprot ID   -
Organism   Streptococcus suis strain WUSS351     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 119708..130745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M06_RS00755 (E8M06_00755) - 122410..122775 (+) 366 WP_024395451.1 DUF1033 family protein -
  E8M06_RS00760 (E8M06_00760) - 122810..123760 (-) 951 WP_136581014.1 S66 peptidase family protein -
  E8M06_RS00765 (E8M06_00765) comYA 123846..124796 (+) 951 WP_136581015.1 competence type IV pilus ATPase ComGA Machinery gene
  E8M06_RS00770 (E8M06_00770) comYB 124708..125745 (+) 1038 WP_247904444.1 competence type IV pilus assembly protein ComGB Machinery gene
  E8M06_RS00775 (E8M06_00775) comYC 125747..126028 (+) 282 WP_105145695.1 competence type IV pilus major pilin ComGC Machinery gene
  E8M06_RS00780 (E8M06_00780) comGD 126009..126416 (+) 408 WP_136581016.1 competence type IV pilus minor pilin ComGD -
  E8M06_RS00785 (E8M06_00785) comYE 126388..126681 (+) 294 WP_044680789.1 competence type IV pilus minor pilin ComGE Machinery gene
  E8M06_RS00790 (E8M06_00790) comGF/cglF 126668..127102 (+) 435 WP_044687018.1 competence type IV pilus minor pilin ComGF Machinery gene
  E8M06_RS00795 (E8M06_00795) comGG 127080..127490 (+) 411 WP_024395444.1 competence type IV pilus minor pilin ComGG -
  E8M06_RS00800 (E8M06_00800) comYH 127547..128500 (+) 954 WP_044778430.1 class I SAM-dependent methyltransferase Machinery gene
  E8M06_RS00805 (E8M06_00805) - 128550..129737 (+) 1188 WP_014637319.1 acetate kinase -
  E8M06_RS00810 (E8M06_00810) - 130052..130603 (+) 552 WP_136581017.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38899.78 Da        Isoelectric Point: 9.4808

>NTDB_id=358828 E8M06_RS00770 WP_247904444.1 124708..125745(+) (comYB) [Streptococcus suis strain WUSS351]
MNKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLSGLSLVAVLAGMVWFRKTSKIKVFSCLSALPFFGKLHQTYLTAYYAREWGSLIGQGLDLPQIVGLMQS
QQSQLFREIGQDLERSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=358828 E8M06_RS00770 WP_247904444.1 124708..125745(+) (comYB) [Streptococcus suis strain WUSS351]
ATGAACAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCCAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGACGGGTTGCTGGCAGGCAAACCCTTTTCGAGTTTACTG
GCAGATTTGCGTTTTTCAGATGCGGTGGTCACACAGGTGGCTTTGGCAGAAGTTCATGGTAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTAGCGACCTATCCGATTATCTTAC
TGGGTTTTTTACTCTTGATTATGCTGGGTTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGTAATGCAGCGACCGTG
CTGATCAATCATCTACCGACCATCTTTTTATCTCTAAGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACTAGCAAAATTAAGGTCTTTTCCTGCTTGTCAGCTCTGCCATTTTTCGGAAAACTCCACCAAACCTACCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCTTGATGCAATCG
CAGCAGTCGCAGCTCTTTCGGGAGATTGGGCAGGACCTGGAGCGGTCGCTTTCCAATGGTCAGAGTTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTACGGTCAGGTCAAGTCCAAGTTGGGTAGCGAGT
TGACAGTTTATGCGGCTGAATGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTAATCCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCGGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

62.865

99.13

0.623
  comYB Streptococcus mutans UA140

59.767

99.42

0.594
  comYB Streptococcus mutans UA159

59.767

99.42

0.594
  comGB/cglB Streptococcus mitis NCTC 12261

60.597

97.101

0.588
  comGB/cglB Streptococcus mitis SK321

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae Rx1

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae D39

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae R6

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae TIGR4

59.701

97.101

0.58
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493

Multiple sequence alignment