Detailed information    

insolico Bioinformatically predicted

Overview

Name   ssbA   Type   Machinery gene
Locus tag   ETT50_RS05265 Genome accession   NZ_CP035449
Coordinates   1012221..1012613 (-) Length   130 a.a.
NCBI ID   WP_011017370.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm56     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 982221..1024207 1012221..1012613 within 0


Gene organization within MGE regions


Location: 982221..1024207
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT50_RS05070 (ETT50_05070) slc2 982221..983522 (-) 1302 WP_146708729.1 LPXTG-anchored collagen-like adhesin Scl2/SclB -
  ETT50_RS05075 (ETT50_05075) - 983869..984384 (-) 516 Protein_922 elongation factor 4 -
  ETT50_RS05080 (ETT50_05080) prx 984616..984798 (-) 183 WP_029714017.1 hypothetical protein Regulator
  ETT50_RS05085 (ETT50_05085) - 984997..985206 (-) 210 WP_011054450.1 helix-turn-helix domain-containing protein -
  ETT50_RS09430 - 985360..985506 (+) 147 WP_011054449.1 hypothetical protein -
  ETT50_RS05090 (ETT50_05090) - 985647..985898 (+) 252 WP_011054448.1 hypothetical protein -
  ETT50_RS05095 (ETT50_05095) - 986162..986401 (+) 240 WP_011054447.1 hypothetical protein -
  ETT50_RS05100 (ETT50_05100) - 986459..986815 (+) 357 WP_011054446.1 hypothetical protein -
  ETT50_RS05105 (ETT50_05105) - 986931..988139 (-) 1209 WP_032465153.1 glucosaminidase domain-containing protein -
  ETT50_RS05110 (ETT50_05110) - 988250..988435 (-) 186 WP_002990010.1 holin -
  ETT50_RS05115 (ETT50_05115) - 988432..988728 (-) 297 WP_002990012.1 hypothetical protein -
  ETT50_RS05120 (ETT50_05120) - 988739..989371 (-) 633 WP_032465154.1 hypothetical protein -
  ETT50_RS05125 (ETT50_05125) - 989374..989802 (-) 429 WP_002988448.1 DUF1617 family protein -
  ETT50_RS05130 (ETT50_05130) - 989814..991700 (-) 1887 WP_146708730.1 gp58-like family protein -
  ETT50_RS05135 (ETT50_05135) hylP 991715..992731 (-) 1017 WP_032464987.1 hyaluronidase HylP -
  ETT50_RS05140 (ETT50_05140) - 992731..994779 (-) 2049 WP_032464986.1 phage tail spike protein -
  ETT50_RS05145 (ETT50_05145) - 994776..995546 (-) 771 WP_011017392.1 distal tail protein Dit -
  ETT50_RS05150 (ETT50_05150) - 995559..999659 (-) 4101 WP_032464985.1 phage tail tape measure protein -
  ETT50_RS05160 (ETT50_05160) gpG 999885..1000187 (-) 303 WP_011017390.1 phage tail assembly chaperone G -
  ETT50_RS05165 (ETT50_05165) - 1000280..1000864 (-) 585 WP_011017389.1 major tail protein -
  ETT50_RS05170 (ETT50_05170) - 1000876..1001256 (-) 381 WP_011017388.1 hypothetical protein -
  ETT50_RS05175 (ETT50_05175) - 1001249..1001647 (-) 399 WP_011017387.1 HK97 gp10 family phage protein -
  ETT50_RS05180 (ETT50_05180) - 1001649..1002011 (-) 363 WP_011017386.1 hypothetical protein -
  ETT50_RS05185 (ETT50_05185) - 1002004..1002312 (-) 309 WP_011017385.1 hypothetical protein -
  ETT50_RS09435 - 1002312..1002485 (-) 174 WP_011017384.1 hypothetical protein -
  ETT50_RS05190 (ETT50_05190) - 1002499..1003632 (-) 1134 WP_011017383.1 phage major capsid protein -
  ETT50_RS05195 (ETT50_05195) - 1003649..1004455 (-) 807 WP_011017382.1 head maturation protease, ClpP-related -
  ETT50_RS05200 (ETT50_05200) - 1004436..1005623 (-) 1188 WP_011017381.1 phage portal protein -
  ETT50_RS05205 (ETT50_05205) - 1005776..1005988 (-) 213 WP_136260634.1 hypothetical protein -
  ETT50_RS05210 (ETT50_05210) - 1005991..1007721 (-) 1731 WP_011017380.1 terminase large subunit domain-containing protein -
  ETT50_RS05215 (ETT50_05215) - 1007734..1008051 (-) 318 WP_011017379.1 P27 family phage terminase small subunit -
  ETT50_RS05220 (ETT50_05220) - 1008192..1008497 (-) 306 WP_011017378.1 HNH endonuclease -
  ETT50_RS05225 (ETT50_05225) - 1008490..1008876 (-) 387 WP_011017377.1 hypothetical protein -
  ETT50_RS05230 (ETT50_05230) - 1008902..1009105 (-) 204 WP_032464984.1 hypothetical protein -
  ETT50_RS05235 (ETT50_05235) - 1009163..1009456 (-) 294 WP_011017375.1 hypothetical protein -
  ETT50_RS05240 (ETT50_05240) - 1009610..1010185 (-) 576 WP_011054435.1 site-specific integrase -
  ETT50_RS05245 (ETT50_05245) - 1010345..1010746 (-) 402 WP_011017373.1 hypothetical protein -
  ETT50_RS05250 (ETT50_05250) - 1010761..1011588 (-) 828 WP_011017372.1 prohibitin family protein -
  ETT50_RS05255 (ETT50_05255) - 1011590..1011928 (-) 339 WP_011017371.1 helix-turn-helix domain-containing protein -
  ETT50_RS05260 (ETT50_05260) - 1011925..1012206 (-) 282 WP_011054431.1 hypothetical protein -
  ETT50_RS05265 (ETT50_05265) ssbA 1012221..1012613 (-) 393 WP_011017370.1 single-stranded DNA-binding protein Machinery gene
  ETT50_RS05270 (ETT50_05270) - 1012610..1012831 (-) 222 WP_011017369.1 hypothetical protein -
  ETT50_RS05275 (ETT50_05275) - 1012828..1013307 (-) 480 WP_032464990.1 DUF1642 domain-containing protein -
  ETT50_RS05280 (ETT50_05280) - 1013312..1013944 (-) 633 WP_011054428.1 N-6 DNA methylase -
  ETT50_RS05285 (ETT50_05285) - 1013946..1014230 (-) 285 WP_032464983.1 hypothetical protein -
  ETT50_RS05290 (ETT50_05290) - 1014240..1014509 (-) 270 WP_023610894.1 hypothetical protein -
  ETT50_RS05295 (ETT50_05295) - 1014526..1014732 (-) 207 WP_011054425.1 hypothetical protein -
  ETT50_RS05300 (ETT50_05300) - 1014746..1014973 (-) 228 WP_011054424.1 hypothetical protein -
  ETT50_RS05305 (ETT50_05305) - 1014973..1015785 (-) 813 WP_032464982.1 ATP-binding protein -
  ETT50_RS05310 (ETT50_05310) - 1015785..1016549 (-) 765 WP_032464981.1 conserved phage C-terminal domain-containing protein -
  ETT50_RS05315 (ETT50_05315) dnaB 1016542..1017882 (-) 1341 WP_032464980.1 replicative DNA helicase -
  ETT50_RS05320 (ETT50_05320) - 1017869..1018057 (-) 189 WP_032464979.1 hypothetical protein -
  ETT50_RS05325 (ETT50_05325) - 1018178..1018369 (-) 192 WP_011017359.1 hypothetical protein -
  ETT50_RS05330 (ETT50_05330) - 1018462..1018719 (-) 258 WP_011054421.1 hypothetical protein -
  ETT50_RS05335 (ETT50_05335) - 1018793..1019512 (-) 720 WP_011017357.1 ORF6C domain-containing protein -
  ETT50_RS05340 (ETT50_05340) - 1019564..1020064 (+) 501 WP_032464978.1 hypothetical protein -
  ETT50_RS09545 - 1020184..1020318 (-) 135 WP_011017356.1 hypothetical protein -
  ETT50_RS05345 (ETT50_05345) - 1020392..1020604 (-) 213 WP_011054420.1 helix-turn-helix domain-containing protein -
  ETT50_RS05350 (ETT50_05350) - 1020639..1020914 (-) 276 WP_011017354.1 hypothetical protein -
  ETT50_RS05355 (ETT50_05355) - 1021203..1021553 (+) 351 WP_011017353.1 helix-turn-helix domain-containing protein -
  ETT50_RS05360 (ETT50_05360) - 1021557..1021949 (+) 393 WP_011017352.1 ImmA/IrrE family metallo-endopeptidase -
  ETT50_RS05365 (ETT50_05365) - 1021960..1022700 (+) 741 WP_011017351.1 type II toxin-antitoxin system PemK/MazF family toxin -
  ETT50_RS05370 (ETT50_05370) - 1023011..1024207 (+) 1197 WP_011017350.1 site-specific integrase -

Sequence

Protein


Download         Length: 130 a.a.        Molecular weight: 14755.61 Da        Isoelectric Point: 6.3209

>NTDB_id=342194 ETT50_RS05265 WP_011017370.1 1012221..1012613(-) (ssbA) [Streptococcus pyogenes strain emm56]
MINNVVLIGRLTKDVELRYTPSQVACAQFTLAVNRNFKNQDGQKEADFINCVIWRKSAENLSNWAKKGQLIAITGRIQTR
NYENQQGQRVYVTEVVAESFQILEKRDNTANTSSLADSMPDYGPEPDLPF

Nucleotide


Download         Length: 393 bp        

>NTDB_id=342194 ETT50_RS05265 WP_011017370.1 1012221..1012613(-) (ssbA) [Streptococcus pyogenes strain emm56]
ATGATCAATAACGTTGTTTTGATTGGCCGATTAACAAAAGATGTTGAGCTACGCTATACACCAAGTCAAGTAGCTTGCGC
ACAGTTTACTTTAGCAGTTAATCGTAATTTTAAAAATCAAGATGGGCAAAAAGAGGCTGACTTTATCAATTGTGTCATCT
GGCGAAAGTCTGCCGAGAATTTATCAAACTGGGCTAAAAAAGGGCAATTGATTGCAATAACAGGACGCATACAGACTCGT
AATTATGAAAACCAGCAAGGACAACGTGTCTATGTTACGGAAGTTGTCGCAGAAAGCTTCCAGATTTTGGAGAAGCGTGA
TAACACTGCAAACACAAGCAGTTTAGCTGATAGCATGCCAGACTATGGACCAGAACCAGATTTACCATTTTAG

Domains

Predicted by InterproScan.

Single-strand binding protein family (SSB)

(2-102)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

68.224

82.308

0.562
  ssb Latilactobacillus sakei subsp. sakei 23K

66.972

83.846

0.562
  ssbB Streptococcus sobrinus strain NIDR 6715-7

48.148

100

0.5
  ssbB/cilA Streptococcus pneumoniae TIGR4

44.853

100

0.469
  ssbB/cilA Streptococcus mitis NCTC 12261

44.853

100

0.469
  ssbB/cilA Streptococcus pneumoniae Rx1

44.118

100

0.462
  ssbB/cilA Streptococcus pneumoniae R6

44.118

100

0.462
  ssbB/cilA Streptococcus pneumoniae D39

44.118

100

0.462
  ssbB/cilA Streptococcus mitis SK321

43.704

100

0.454
  ssbA Streptococcus mutans UA159

43.704

100

0.454
  ssbB Bacillus subtilis subsp. subtilis str. 168

53.774

81.538

0.438
  ssbB Lactococcus lactis subsp. cremoris KW2

42.636

99.231

0.423

Multiple sequence alignment