Detailed information
Bioinformatically predicted
Overview
| Name | comX/comX2 | Type | Regulator |
| Locus tag | EQH28_RS00065 | Genome accession | NZ_CP035252 |
| Coordinates | 14255..14734 (+) | Length | 159 a.a. |
| NCBI ID | WP_000588897.1 | Uniprot ID | Q9R2W8 |
| Organism | Streptococcus pneumoniae strain TVO_1901934 | ||
| Function | activate transcription of late competence genes (predicted from homology) Competence regulation |
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Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 12175..44275 | 14255..14734 | within | 0 |
Gene organization within MGE regions
Location: 12175..44275
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQH28_RS00060 (EQH28_00060) | ftsH | 12175..14133 (+) | 1959 | WP_000744551.1 | ATP-dependent zinc metalloprotease FtsH | - |
| EQH28_RS00065 (EQH28_00065) | comX/comX2 | 14255..14734 (+) | 480 | WP_000588897.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| EQH28_RS00100 (EQH28_00100) | - | 20226..21072 (+) | 847 | Protein_14 | IS630 family transposase | - |
| EQH28_RS00105 (EQH28_00105) | - | 21107..21904 (-) | 798 | Protein_15 | transposase | - |
| EQH28_RS00110 (EQH28_00110) | comW | 22170..22406 (+) | 237 | WP_000939544.1 | sigma(X)-activator ComW | Regulator |
| EQH28_RS00115 (EQH28_00115) | - | 22637..23923 (+) | 1287 | WP_000205044.1 | adenylosuccinate synthase | - |
| EQH28_RS00120 (EQH28_00120) | tadA | 24124..24591 (+) | 468 | WP_000291870.1 | tRNA adenosine(34) deaminase TadA | - |
| EQH28_RS00130 (EQH28_00130) | - | 24800..25498 (-) | 699 | WP_001106362.1 | site-specific integrase | - |
| EQH28_RS00135 (EQH28_00135) | - | 25588..25935 (-) | 348 | WP_001839379.1 | hypothetical protein | - |
| EQH28_RS00140 (EQH28_00140) | - | 25996..27066 (-) | 1071 | WP_000401841.1 | type I restriction endonuclease | - |
| EQH28_RS00145 (EQH28_00145) | - | 27083..27463 (-) | 381 | WP_000170931.1 | ImmA/IrrE family metallo-endopeptidase | - |
| EQH28_RS00150 (EQH28_00150) | - | 27476..27739 (-) | 264 | WP_000285962.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQH28_RS00155 (EQH28_00155) | - | 27739..27972 (-) | 234 | WP_000156419.1 | hypothetical protein | - |
| EQH28_RS00160 (EQH28_00160) | - | 27972..28340 (-) | 369 | WP_000464160.1 | helix-turn-helix domain-containing protein | - |
| EQH28_RS00165 (EQH28_00165) | - | 28912..29103 (+) | 192 | WP_001112859.1 | DNA-binding protein | - |
| EQH28_RS00170 (EQH28_00170) | - | 29126..29329 (+) | 204 | WP_001247549.1 | hypothetical protein | - |
| EQH28_RS00175 (EQH28_00175) | - | 29484..29651 (-) | 168 | WP_000024181.1 | YjzC family protein | - |
| EQH28_RS00180 (EQH28_00180) | - | 29656..30036 (+) | 381 | Protein_29 | autolysin | - |
| EQH28_RS00185 (EQH28_00185) | - | 30256..30435 (-) | 180 | WP_001209433.1 | hypothetical protein | - |
| EQH28_RS00190 | - | 30577..30726 (-) | 150 | WP_001030863.1 | hypothetical protein | - |
| EQH28_RS00195 (EQH28_00190) | - | 31031..31474 (+) | 444 | WP_000701992.1 | dUTP diphosphatase | - |
| EQH28_RS00200 (EQH28_00195) | - | 31476..31991 (+) | 516 | WP_000691236.1 | histidine phosphatase family protein | - |
| EQH28_RS00205 (EQH28_00200) | radA | 32005..33366 (+) | 1362 | WP_074017595.1 | DNA repair protein RadA | Machinery gene |
| EQH28_RS00210 (EQH28_00205) | - | 33439..33936 (+) | 498 | WP_001809420.1 | carbonic anhydrase | - |
| EQH28_RS00215 (EQH28_00210) | - | 33961..34744 (+) | 784 | Protein_36 | PrsW family glutamic-type intramembrane protease | - |
| EQH28_RS00220 (EQH28_00215) | - | 34889..35857 (+) | 969 | WP_000010157.1 | ribose-phosphate diphosphokinase | - |
| EQH28_RS00225 (EQH28_00220) | - | 35991..36272 (-) | 282 | Protein_38 | ISL3 family transposase | - |
| EQH28_RS00230 | - | 36399..37306 (-) | 908 | Protein_39 | Rpn family recombination-promoting nuclease/putative transposase | - |
| EQH28_RS00235 (EQH28_00240) | polA | 37562..40195 (+) | 2634 | WP_000358437.1 | DNA polymerase I | - |
| EQH28_RS00240 (EQH28_00245) | - | 40280..40717 (+) | 438 | WP_061751321.1 | CoA-binding protein | - |
| EQH28_RS00245 (EQH28_00250) | - | 41180..42190 (-) | 1011 | WP_000009143.1 | YeiH family protein | - |
| EQH28_RS00250 (EQH28_00255) | - | 42339..43508 (+) | 1170 | WP_000366378.1 | pyridoxal phosphate-dependent aminotransferase | - |
| EQH28_RS00255 (EQH28_00260) | recO | 43505..44275 (+) | 771 | WP_000616161.1 | DNA repair protein RecO | - |
Sequence
Protein
Download Length: 159 a.a. Molecular weight: 19873.52 Da Isoelectric Point: 7.3797
>NTDB_id=337802 EQH28_RS00065 WP_000588897.1 14255..14734(+) (comX/comX2) [Streptococcus pneumoniae strain TVO_1901934]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH
Nucleotide
Download Length: 480 bp
>NTDB_id=337802 EQH28_RS00065 WP_000588897.1 14255..14734(+) (comX/comX2) [Streptococcus pneumoniae strain TVO_1901934]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCATTAG
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCATTAG
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.