Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   EQH31_RS11235 Genome accession   NZ_CP035249
Coordinates   1980570..1980761 (-) Length   63 a.a.
NCBI ID   WP_025169467.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901938     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1975570..1985761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH31_RS10215 (EQH31_10830) - 1975628..1976503 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  EQH31_RS10220 (EQH31_10835) pstC 1976621..1977484 (+) 864 WP_000165893.1 phosphate ABC transporter permease subunit PstC -
  EQH31_RS10225 (EQH31_10840) pstA 1977477..1978292 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  EQH31_RS10230 (EQH31_10845) pstB 1978294..1979046 (+) 753 WP_000536450.1 phosphate ABC transporter ATP-binding protein PstB -
  EQH31_RS10235 (EQH31_10850) phoU 1979061..1979711 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  EQH31_RS10240 (EQH31_10855) - 1979752..1980204 (+) 453 Protein_1999 transposase -
  EQH31_RS11230 - 1980319..1980570 (-) 252 WP_001818970.1 hypothetical protein -
  EQH31_RS11235 comR 1980570..1980761 (-) 192 WP_025169467.1 helix-turn-helix domain-containing protein Regulator
  EQH31_RS10250 (EQH31_10865) - 1980973..1981989 (+) 1017 WP_000415116.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  EQH31_RS10255 (EQH31_10870) galU 1982011..1982910 (+) 900 WP_000202235.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  EQH31_RS10260 (EQH31_10875) - 1982982..1983659 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  EQH31_RS10265 (EQH31_10880) - 1983643..1984182 (-) 540 WP_000834303.1 5-formyltetrahydrofolate cyclo-ligase -
  EQH31_RS10270 (EQH31_10885) - 1984194..1985324 (-) 1131 WP_000885071.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 63 a.a.        Molecular weight: 7280.52 Da        Isoelectric Point: 10.6965

>NTDB_id=337723 EQH31_RS11235 WP_025169467.1 1980570..1980761(-) (comR) [Streptococcus pneumoniae strain TVO_1901938]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLGGVKITS

Nucleotide


Download         Length: 192 bp        

>NTDB_id=337723 EQH31_RS11235 WP_025169467.1 1980570..1980761(-) (comR) [Streptococcus pneumoniae strain TVO_1901938]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAACACTAACAAAGTTAAAATATATCGCTG
AACGTTTGGGGGGGGTGAAGATTACAAGTTGA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(8-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

57.895

90.476

0.524
  comR Streptococcus pyogenes MGAS8232

57.895

90.476

0.524
  comR Streptococcus mutans UA159

57.895

90.476

0.524
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

60

87.302

0.524
  comR Streptococcus salivarius strain HSISS4

56.604

84.127

0.476
  comR Streptococcus salivarius SK126

56.604

84.127

0.476
  comR Streptococcus suis D9

53.571

88.889

0.476
  comR Streptococcus suis 05ZYH33

53.571

88.889

0.476
  comR Streptococcus suis P1/7

53.571

88.889

0.476
  comR Streptococcus thermophilus LMD-9

54.717

84.127

0.46
  comR Streptococcus thermophilus LMG 18311

54.717

84.127

0.46
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

50

92.063

0.46
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

61.702

74.603

0.46

Multiple sequence alignment