Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   EQH32_RS10900 Genome accession   NZ_CP035248
Coordinates   1915359..1915553 (-) Length   64 a.a.
NCBI ID   WP_001844285.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901939     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1910359..1920553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH32_RS09915 (EQH32_10435) - 1910417..1911292 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  EQH32_RS09920 (EQH32_10440) pstC 1911410..1912273 (+) 864 WP_000165893.1 phosphate ABC transporter permease subunit PstC -
  EQH32_RS09925 (EQH32_10445) pstA 1912266..1913081 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  EQH32_RS09930 (EQH32_10450) pstB 1913083..1913835 (+) 753 WP_000536450.1 phosphate ABC transporter ATP-binding protein PstB -
  EQH32_RS09935 (EQH32_10455) phoU 1913850..1914500 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  EQH32_RS09940 (EQH32_10460) - 1914541..1914993 (+) 453 Protein_1936 transposase -
  EQH32_RS10895 - 1915108..1915359 (-) 252 WP_001818970.1 hypothetical protein -
  EQH32_RS10900 comR 1915359..1915553 (-) 195 WP_001844285.1 helix-turn-helix domain-containing protein Regulator
  EQH32_RS09950 (EQH32_10470) - 1915765..1916781 (+) 1017 WP_000415116.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  EQH32_RS09955 (EQH32_10475) galU 1916803..1917702 (+) 900 WP_000202235.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  EQH32_RS09960 (EQH32_10480) - 1917774..1918451 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  EQH32_RS09965 (EQH32_10485) - 1918435..1918974 (-) 540 WP_000834303.1 5-formyltetrahydrofolate cyclo-ligase -
  EQH32_RS09970 (EQH32_10490) - 1918986..1920116 (-) 1131 WP_000885071.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 64 a.a.        Molecular weight: 7337.58 Da        Isoelectric Point: 10.6965

>NTDB_id=337644 EQH32_RS10900 WP_001844285.1 1915359..1915553(-) (comR) [Streptococcus pneumoniae strain TVO_1901939]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLGGGVKITS

Nucleotide


Download         Length: 195 bp        

>NTDB_id=337644 EQH32_RS10900 WP_001844285.1 1915359..1915553(-) (comR) [Streptococcus pneumoniae strain TVO_1901939]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAACACTAACAAAGTTAAAATATATCGCTG
AACGTTTGGGGGGGGGGGTGAAGATTACAAGTTGA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(8-57)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

56.667

93.75

0.531
  comR Streptococcus pyogenes MGAS8232

56.667

93.75

0.531
  comR Streptococcus mutans UA159

57.895

89.063

0.516
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

61.111

84.375

0.516
  comR Streptococcus suis P1/7

52.542

92.188

0.484
  comR Streptococcus suis 05ZYH33

52.542

92.188

0.484
  comR Streptococcus suis D9

52.542

92.188

0.484
  comR Streptococcus salivarius SK126

53.571

87.5

0.469
  comR Streptococcus salivarius strain HSISS4

53.571

87.5

0.469
  comR Streptococcus thermophilus LMG 18311

51.786

87.5

0.453
  comR Streptococcus thermophilus LMD-9

51.786

87.5

0.453
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

61.702

73.438

0.453
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

50.877

89.063

0.453

Multiple sequence alignment