Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   EQH33_RS09355 Genome accession   NZ_CP035247
Coordinates   1840189..1841130 (-) Length   313 a.a.
NCBI ID   WP_000249556.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901940     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1835189..1846130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH33_RS09315 (EQH33_09865) comYH 1835675..1836628 (-) 954 WP_000345101.1 class I SAM-dependent methyltransferase Machinery gene
  EQH33_RS09320 (EQH33_09870) - 1836689..1837283 (-) 595 Protein_1828 class I SAM-dependent methyltransferase -
  EQH33_RS09325 (EQH33_09875) comGG/cglG 1837420..1837833 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH33_RS09330 (EQH33_09880) comGF/cglF 1837811..1838272 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH33_RS09335 (EQH33_09885) comGE/cglE 1838235..1838537 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH33_RS09340 (EQH33_09890) comGD/cglD 1838500..1838904 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH33_RS09345 (EQH33_09895) comGC/cglC 1838897..1839223 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  EQH33_RS09350 (EQH33_09900) comGB/cglB 1839225..1840241 (-) 1017 WP_076750272.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH33_RS09355 (EQH33_09905) comGA/cglA/cilD 1840189..1841130 (-) 942 WP_000249556.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH33_RS09360 (EQH33_09910) - 1841206..1841571 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH33_RS09365 (EQH33_09915) - 1841722..1842780 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -
  EQH33_RS09370 (EQH33_09920) nagA 1842943..1844094 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  EQH33_RS09375 (EQH33_09925) - 1844247..1846064 (-) 1818 WP_001220920.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35534.46 Da        Isoelectric Point: 6.0083

>NTDB_id=337551 EQH33_RS09355 WP_000249556.1 1840189..1841130(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain TVO_1901940]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFASRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=337551 EQH33_RS09355 WP_000249556.1 1840189..1841130(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain TVO_1901940]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGCTCGGCTCGGAAAAAAGGGGCGCAAGACATTTATTTTGTCCCCAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGATATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae D39

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae R6

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

99.042

100

0.99
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.805

100

0.968
  comYA Streptococcus gordonii str. Challis substr. CH1

78.387

99.042

0.776
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

99.042

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

41.912

86.901

0.364

Multiple sequence alignment