Detailed information NTG0337546

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EQH33_RS09330
• Genome accession: NZ_CP035247
• Coordinates: 1837811..1838272 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901940
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1832811..1843272

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH33_RS09300 (EQH33_09850)	-	1833115..1833939 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
EQH33_RS09305 (EQH33_09855)	rnpA	1833914..1834285 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH33_RS10455	-	1834302..1834433 (-)	132	WP_000768904.1	hypothetical protein	-
EQH33_RS09310 (EQH33_09860)	-	1834434..1835624 (-)	1191	WP_000167766.1	acetate kinase	-
EQH33_RS09315 (EQH33_09865)	comYH	1835675..1836628 (-)	954	WP_000345101.1	class I SAM-dependent methyltransferase	Machinery gene
EQH33_RS09320 (EQH33_09870)	-	1836689..1837283 (-)	595	Protein_1828	class I SAM-dependent methyltransferase	-
EQH33_RS09325 (EQH33_09875)	comGG/cglG	1837420..1837833 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH33_RS09330 (EQH33_09880)	comGF/cglF	1837811..1838272 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH33_RS09335 (EQH33_09885)	comGE/cglE	1838235..1838537 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH33_RS09340 (EQH33_09890)	comGD/cglD	1838500..1838904 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH33_RS09345 (EQH33_09895)	comGC/cglC	1838897..1839223 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
EQH33_RS09350 (EQH33_09900)	comGB/cglB	1839225..1840241 (-)	1017	WP_076750272.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH33_RS09355 (EQH33_09905)	comGA/cglA/cilD	1840189..1841130 (-)	942	WP_000249556.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH33_RS09360 (EQH33_09910)	-	1841206..1841571 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH33_RS09365 (EQH33_09915)	-	1841722..1842780 (-)	1059	WP_000649466.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=337546 EQH33_RS09330 WP_000250542.1 1837811..1838272(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901940]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=337546 EQH33_RS09330 WP_000250542.1 1837811..1838272(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901940]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909