Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EQH35_RS09570 Genome accession   NZ_CP035245
Coordinates   1834087..1834413 (-) Length   108 a.a.
NCBI ID   WP_000738636.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901943     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1829087..1839413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH35_RS09530 (EQH35_10065) rnpA 1829104..1829475 (-) 372 WP_000739244.1 ribonuclease P protein component -
  EQH35_RS10675 - 1829492..1829623 (-) 132 WP_000768904.1 hypothetical protein -
  EQH35_RS09535 (EQH35_10070) - 1829624..1830814 (-) 1191 WP_000167765.1 acetate kinase -
  EQH35_RS09540 (EQH35_10075) comYH 1830865..1831818 (-) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  EQH35_RS09545 (EQH35_10080) - 1831879..1832473 (-) 595 Protein_1881 class I SAM-dependent methyltransferase -
  EQH35_RS09550 (EQH35_10085) comGG/cglG 1832610..1833023 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH35_RS09555 (EQH35_10090) comGF/cglF 1833001..1833462 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH35_RS09560 (EQH35_10095) comGE/cglE 1833425..1833727 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH35_RS09565 (EQH35_10100) comGD/cglD 1833690..1834094 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH35_RS09570 (EQH35_10105) comGC/cglC 1834087..1834413 (-) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  EQH35_RS09575 (EQH35_10110) comGB/cglB 1834415..1835431 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH35_RS09580 (EQH35_10115) comGA/cglA/cilD 1835379..1836320 (-) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH35_RS09585 (EQH35_10120) - 1836396..1836761 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH35_RS09590 (EQH35_10125) - 1836912..1837970 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  EQH35_RS09595 (EQH35_10130) nagA 1838133..1839284 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12208.39 Da        Isoelectric Point: 10.0305

>NTDB_id=337392 EQH35_RS09570 WP_000738636.1 1834087..1834413(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1901943]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKE
DGRITEEQAKAYKEYNDKNVGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=337392 EQH35_RS09570 WP_000738636.1 1834087..1834413(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1901943]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACAATGATAAAAATGTGGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae TIGR4

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae Rx1

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae D39

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae R6

95.37

100

0.954
  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

93.878

90.741

0.852
  comYC Streptococcus gordonii str. Challis substr. CH1

71.875

88.889

0.639
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comYC Streptococcus suis isolate S10

67.901

75

0.509
  comGC Staphylococcus aureus MW2

48.837

79.63

0.389
  comGC Staphylococcus aureus N315

48.837

79.63

0.389
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment