Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   SEQ_RS00675 Genome accession   NC_012471
Coordinates   120990..121313 (+) Length   107 a.a.
NCBI ID   WP_012514782.1    Uniprot ID   B4U056
Organism   Streptococcus equi subsp. equi 4047     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115990..126313
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEQ_RS00655 (SEQ_0105) - 116250..118253 (+) 2004 WP_012678808.1 DUF1430 domain-containing protein -
  SEQ_RS00660 (SEQ_0106) - 118255..118902 (+) 648 WP_012678809.1 ATP-binding cassette domain-containing protein -
  SEQ_RS00665 (SEQ_0107) comGA/cglA 119084..120022 (+) 939 WP_012678810.1 competence type IV pilus ATPase ComGA Machinery gene
  SEQ_RS00670 (SEQ_0108) comYB 119955..120989 (+) 1035 WP_012678811.1 competence type IV pilus assembly protein ComGB Machinery gene
  SEQ_RS00675 (SEQ_0109) comGC/cglC 120990..121313 (+) 324 WP_012514782.1 competence type IV pilus major pilin ComGC Machinery gene
  SEQ_RS00680 (SEQ_0110) comGD 121291..121716 (+) 426 WP_012678812.1 competence type IV pilus minor pilin ComGD -
  SEQ_RS00685 (SEQ_0111) comGE 121673..121963 (+) 291 WP_012678813.1 competence type IV pilus minor pilin ComGE -
  SEQ_RS00690 (SEQ_0112) comYF 121950..122384 (+) 435 WP_012678814.1 competence type IV pilus minor pilin ComGF Machinery gene
  SEQ_RS00695 (SEQ_0113) comGG 122362..122724 (+) 363 WP_012678815.1 competence type IV pilus minor pilin ComGG -
  SEQ_RS11470 (SEQ_0115) - 122790..124132 (+) 1343 Protein_108 IS3 family transposase -
  SEQ_RS00710 (SEQ_0117) comYH 124217..125170 (+) 954 WP_012678816.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 12149.19 Da        Isoelectric Point: 8.4057

>NTDB_id=33499 SEQ_RS00675 WP_012514782.1 120990..121313(+) (comGC/cglC) [Streptococcus equi subsp. equi 4047]
MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQE
DGSISDKQQKAYQDYYAKHKDEAKKLN

Nucleotide


Download         Length: 324 bp        

>NTDB_id=33499 SEQ_RS00675 WP_012514782.1 120990..121313(+) (comGC/cglC) [Streptococcus equi subsp. equi 4047]
ATGAAAATGAGATTATCAATCTTAAAAGATCAAGGTGTTCAGGCCTTCACTTTACTGGAAATGCTTCTGGTTTTGTTAAT
CATTAGTGTTTTGATGCTGTTATTTGTTCCAAATTTAAGTAAACAAAAGGATAAGGTGACAGACACAGGCAATGCTGCGG
TGGTAAAGCTGGTTGAAAATCAGGCAGAGCTTTATGAATTATCACATGGGGAAAAGCCAAGCCTGAAGCAGCTGCAAGAG
GATGGAAGTATCAGTGACAAGCAGCAAAAGGCTTATCAGGATTATTATGCAAAGCATAAAGATGAAGCTAAGAAGCTCAA
TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(14-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4U056

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis SK321

59.813

100

0.598
  comGC/cglC Streptococcus pneumoniae Rx1

57.944

100

0.579
  comGC/cglC Streptococcus pneumoniae D39

57.944

100

0.579
  comGC/cglC Streptococcus pneumoniae R6

57.944

100

0.579
  comGC/cglC Streptococcus pneumoniae TIGR4

57.944

100

0.579
  comYC Streptococcus gordonii str. Challis substr. CH1

62.245

91.589

0.57
  comGC/cglC Streptococcus mitis NCTC 12261

61.616

92.523

0.57
  comYC Streptococcus mutans UA140

58.763

90.654

0.533
  comYC Streptococcus mutans UA159

58.763

90.654

0.533
  comGC Lactococcus lactis subsp. cremoris KW2

56.842

88.785

0.505
  comYC Streptococcus suis isolate S10

60

74.766

0.449
  comGC Staphylococcus aureus MW2

50

72.897

0.364
  comGC Staphylococcus aureus N315

50

72.897

0.364

Multiple sequence alignment