Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   SPCG_RS10625 Genome accession   NC_010582
Coordinates   1999058..1999384 (-) Length   108 a.a.
NCBI ID   WP_000738625.1    Uniprot ID   -
Organism   Streptococcus pneumoniae CGSP14     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1994058..2004384
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPCG_RS10580 (SPCG_2008) rnpA 1994076..1994447 (-) 372 WP_000739246.1 ribonuclease P protein component -
  SPCG_RS14075 (SPCG_2009) - 1994464..1994595 (-) 132 WP_000768904.1 hypothetical protein -
  SPCG_RS10585 (SPCG_2010) - 1994596..1995786 (-) 1191 WP_000167766.1 acetate kinase -
  SPCG_RS10590 (SPCG_2011) comYH 1995837..1996790 (-) 954 WP_000345133.1 class I SAM-dependent methyltransferase Machinery gene
  SPCG_RS12795 - 1996851..1997445 (-) 595 Protein_1978 class I SAM-dependent methyltransferase -
  SPCG_RS10605 (SPCG_2014) comGG/cglG 1997548..1997994 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  SPCG_RS10610 (SPCG_2015) comGF/cglF 1997972..1998433 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPCG_RS10615 (SPCG_2016) comGE/cglE 1998396..1998698 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPCG_RS10620 (SPCG_2017) comGD/cglD 1998661..1999065 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPCG_RS10625 (SPCG_2018) comGC/cglC 1999058..1999384 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  SPCG_RS10630 (SPCG_2019) comGB/cglB 1999386..2000402 (-) 1017 WP_078134418.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPCG_RS10635 (SPCG_2020) comGA/cglA/cilD 2000350..2001291 (-) 942 WP_000249573.1 competence type IV pilus ATPase ComGA Machinery gene
  SPCG_RS10640 (SPCG_2021) - 2001367..2001732 (-) 366 WP_000286415.1 DUF1033 family protein -
  SPCG_RS10645 (SPCG_2022) - 2001883..2002941 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  SPCG_RS10650 (SPCG_2023) nagA 2003104..2004255 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12143.28 Da        Isoelectric Point: 10.0055

>NTDB_id=30648 SPCG_RS10625 WP_000738625.1 1999058..1999384(-) (comGC/cglC) [Streptococcus pneumoniae CGSP14]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQG
DGRITEEQVKAYNEYYTKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=30648 SPCG_RS10625 WP_000738625.1 1999058..1999384(-) (comGC/cglC) [Streptococcus pneumoniae CGSP14]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTAGTAGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGATAAAAATGAAGATGCTACTCTGAGCAAGTTACAAGGA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis SK321

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae Rx1

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae D39

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae R6

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae TIGR4

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

92.857

90.741

0.843
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comYC Streptococcus suis isolate S10

64.773

81.481

0.528
  comGC Staphylococcus aureus MW2

47.674

79.63

0.38
  comGC Staphylococcus aureus N315

47.674

79.63

0.38

Multiple sequence alignment